Results 111 to 120 of about 4,102 (209)

Petits ARN C/D et syndrome de Prader-Willi [PDF]

, 2005
International ...
Cavaillé, Jérôme, Vitali, Patrice
core   +2 more sources

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis

Genome Biology, 2017
Background Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein
Jacki E. Heraud-Farlow, Alistair M. Chalk, Sandra E. Linder, Qin Li, Scott Taylor, Joshua M. White, Lokman Pang, Brian J. Liddicoat, Ankita Gupte, Jin Billy Li, Carl R. Walkley   +10 more
doaj   +1 more source

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing

Cell Reports, 2020
Summary: Adenosine-to-inosine RNA editing is catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes that deaminate adenosine to inosine. Although many RNA editing sites are known, few trans regulators have been identified.
Emily C. Freund, Anne L. Sapiro, Qin Li, Sandra Linder, James J. Moresco, John R. Yates, III, Jin Billy Li   +6 more
doaj   +1 more source

Mitochondrial Ribosomal Protein Family in Cancers: Mechanistic Insights and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Mitochondrial ribosomal proteins (MRPs) are the important components of mitoribosome. They are aberrantly expressed in various human cancers. In this review, we introduce the roles of MRPs in tumorigenesis and development by regulating OXPHOS and other mechanisms.
Qian Chen, Yingli Zhang, Jin‐Jian Lu, Ting Li   +3 more
wiley   +1 more source

p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation [PDF]

, 2006
Background RNA-specific adenosine deaminase ADAR1 is ubiquitously expressed in a variety of mammalian cells and tissues. Although its physiological importance in non-nervous tissues has been confirmed by analysis of null mutation phenotypes, few ...
Haifang Wang, Zheng Hou, Yumei Wu, Xue Ma, Xiaoxing Luo, U Kim, MA O'Connell, Y Liu, PH Seeburg, CE Samuel, CX George, CX George, SK Wong, S Sato, JC Hartner, Q Wang, Q Wang, CX George, MS Paul, RW Wagner, S Maas, JH Yang, JM Desterro, W James, W Zhao, R Giavazzi, Y Nie, Y Nie, CR Eckmann, SK Wong, SW Knight, JH Yang, DD Kim, MR Vila, EY Levanon, A Athanasiadis, M Blow   +36 more
core   +1 more source

Involvement of RNA-editing enzyme and multi-factor to motor neuron death in patients with sporadic amyotrophic lateral sclerosis [PDF]

, 2012
科学研究費助成事業(科学研究費補助金)研究成果報告書：基盤研究(C)2009-2011課題番号 ...
TAKUMA HIROSHI, 詫間 浩
core  

A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme

Scientific Reports, 2017
Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miRNAs.
Deepanjan Paul, Ashis Narayan Sinha, Arjun Ray, Megha Lal, Subhashree Nayak, Anchal Sharma, Bharati Mehani, Debasish Mukherjee, Saurabh V. Laddha, Ashish Suri, Chitra Sarkar, Arijit Mukhopadhyay   +11 more
doaj   +1 more source

Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats [PDF]

, 2010
Background Alu repeats in the human transcriptome undergo massive adenosine to inosine RNA editing. This process is selective, as editing efficiency varies greatly among different adenosines.
Yoav Kleinberger, Eli Eisenberg
core   +2 more sources

Genome-wide analysis of consistently RNA edited sites in human blood reveals interactions with mRNA processing genes and suggests correlations with cell types and biological variables

BMC Genomics, 2018
Background A-to-I RNA editing is a co−/post-transcriptional modification catalyzed by ADAR enzymes, that deaminates Adenosines (A) into Inosines (I).
Edoardo Giacopuzzi, Massimo Gennarelli, Chiara Sacco, Alice Filippini, Jessica Mingardi, Chiara Magri, Alessandro Barbon   +6 more
doaj   +1 more source

Comparative RNA editing in autistic and neurotypical cerebella [PDF]

, 2012
Adenosine-to-inosine (A-to-I) RNA editing is a neurodevelopmentally regulated epigenetic modification shown to modulate complex behavior in animals.
Brown, Emery N., Calvo, Sarah E., Collins, C., Eran, A., Kohane, Isaac, Kunkel, Louis M., Li, J. B., Margulies, David M., Markianos, K., McCarthy, J., Rahimov, F., Vatalaro, K.   +11 more
core   +1 more source