Results 91 to 100 of about 6,770,889 (217)

Pan-cancer analysis of ADAR1 with its prognostic relevance in low-grade glioma

Immunobiology
ADAR1, known as the primary enzyme for adenosine-to-inosine RNA editing, has recently been implicated in cancer development through both RNA editing-dependent and −independent pathways.
Qin Yang, Xin Li
doaj   +1 more source

Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing

Advanced Genetics, Volume 6, Issue 4, December 2025.
This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley   +1 more source

The integration of generative artificial intelligence and machine learning in healthcare: Current applications and future directions

Journal of Intelligent Medicine, Volume 2, Issue 4, Page 179-192, December 2025.
Abstract Machine learning (ML) and generative artificial intelligence (GAI) in recent years are rapidly revolutionizing the healthcare industry offering improved precision and efficiency of healthcare delivery. The use of these advanced technologies in healthcare such as medical imaging, drug discoveries, predictive analytics, and personalized medicine
Muhammad Umar, Laiba Shamim, Imshaal Musharaf, Pakeezah Tabasum, Vani Malhotra, Kanza Farhan, Ayesha Hidayat, Muhammad Waqas, Amna Anwar, Maria Qadri, Shahana Reza   +10 more
wiley   +1 more source

HERVs, transposons and human diseases : part 3 [PDF]

, 2012
Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012Part 3 of the article.
Baldacchino, Sandra, Grech, Alfred
core   +1 more source

Air Pollution‐Induced Epigenetic Regulation in Respiratory Diseases: Mechanisms, Dysregulation, and Therapeutic Opportunities

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
Air pollution, a major global health hazard, contributes to asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and lung cancer via four core epigenetic pathways (DNA/RNA methylation, noncoding RNAs, and histone modifications), shaping gene expression and driving disease pathogenesis.
Ruitong Zeng, Jiliu Liu, Guoping Li, Junyi Wang, Anying Xiong, Ying Xiong, Xiang He   +6 more
wiley   +1 more source

Analyzing Public Environmental Awareness Using Advanced Machine Learning for Sustainable Urban Transportation

Sustainable Development, Volume 33, Issue 6, Page 8619-8637, December 2025.
ABSTRACT Environmental awareness and sustainable transportation are critical in addressing climate change and urbanization. This research enhances understanding of environmental awareness through advanced machine learning (ML), focusing on cycling as a key component of sustainable urban mobility.
Mihrimah Özmen
wiley   +1 more source

Narrowing down the candidates of beneficial A-to-I RNA editing by comparing the recoding sites with uneditable counterparts

Nucleus
Adar-mediated adenosine-to-inosine (A-to-I) RNA editing mainly occurs in nucleus and diversifies the transcriptome in a flexible manner. It has been a challenging task to identify beneficial editing sites from the sea of total editing events.
Tianyou Zhao, Ling Ma, Shiwen Xu, Wanzhi Cai, Hu Li, Yuange Duan   +5 more
doaj   +1 more source

An Overview of ADAR Inhibitors: Mechanisms, Applications, and Future Directions

Serican Journal of Medicine
Adenosine deaminases acting on RNA (ADARs) are enzymes responsible for converting adenosine to inosine in double-stranded RNA through a process known as A-to-I editing.
Taufeeque Ali, Qi Cao
semanticscholar   +1 more source

Epigenetics of Homocystinuria, Hydrogen Sulfide, and Circadian Clock Ablation in Cardiovascular–Renal Disease

Current Issues in Molecular Biology
Morning-time heart attacks are associated with an ablation in the sleep-time dip in blood pressure, the mechanism of which is unknown. The epigenetic changes are the hallmark of sleep and circadian clock disruption and homocystinuria (HHcy).
Suresh C. Tyagi
doaj   +1 more source

Deep Brain Stimulation in a Child with Aicardi‐Goutières Syndrome‐7 (AGS7): A Case Report and Literature Review

Movement Disorders Clinical Practice, Volume 12, Issue 12, Page 2375-2378, December 2025.
Sangeetha Yoganathan, Siddharth Seth, Sunita Venkateswaran, Wei Kang Lim, Andrea LeBlanc‐Millar, Sara Breitbart, Vivek Pai, Asif Doja, Alfonso Fasano, George M. Ibrahim, Carolina Gorodetsky   +10 more
wiley   +1 more source