Results 91 to 100 of about 6,398,385 (224)
HERVs, transposons and human diseases : part 3 [PDF]
, 2012 Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012Part 3 of the article.
Baldacchino, Sandra, Grech, Alfred
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Cell Proliferation, EarlyView.CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. [PDF]
, 2015 Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle.
Li, Melody MH +2 more
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Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Plant Biotechnology Journal, EarlyView.Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat +6 more
wiley +1 more source
In vivo RNA editing of point mutations via RNA-guided adenosine deaminases. [PDF]
, 2019 We present in vivo sequence-specific RNA base editing via adenosine deaminases acting on RNA (ADAR) enzymes with associated ADAR guide RNAs (adRNAs). To achieve this, we systematically engineered adRNAs to harness ADARs, and comprehensively evaluated the
Chen, Genghao +7 more
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Philosophical Perspectives, EarlyView.ABSTRACT In a pure event semantics for natural language, the domain of quantification and predication is limited to events and states. I offer pure event semantic analyses of several phenomena, some of which have not been treated before in formal semantics. In the pure event semantics sketched in the second section, nouns are state predicates, and this
Roger Schwarzschild
wiley +1 more source
Host Immune Response Driving SARS-CoV-2 Evolution
Viruses, 2020 The transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of paramount importance in controlling and combating the coronavirus disease 2019 (COVID-19) pandemic.
Rui Wang +4 more
doaj +1 more source
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
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Current progress of digital twin construction using medical imaging
Journal of Applied Clinical Medical Physics, Volume 26, Issue 9, September 2025.Abstract Medical imaging is fundamental to digital twin technology, enabling patient‐specific virtual models of anatomy and physiology. By integrating high‐resolution modalities (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission Tomography (PET), ultrasound) with computational frameworks, recent imaging advances now support ...
Feng Zhao +6 more
wiley +1 more source
Role of non-coding RNAs in the transgenerational epigenetic transmission of the effects of reprotoxicants [PDF]
, 2016 13 p.-1 fig.Non-coding RNAs (ncRNAs) are regulatory elements of gene expression and chromatin structure. Both long and small ncRNAs can also act as inductors and targets of epigenetic programs.
Del Mazo, Jesús, Larriba, E.
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