Results 11 to 20 of about 27,022 (204)

ADCC Assay Protocol

Bio-Protocol, 2014
Antibody-dependent cell-mediated cytotoxicity (ADCC) bridges innate and adaptive immunity, and it involves both humoral and cellular immune responses.
Vikram Srivastava, Zheng Yang, Ivan Hung, Jianqing Xu, Bojian Zheng, Mei-Yun Zhang   +5 more
doaj   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer. [PDF]

Mol Oncol
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Lassche G, van Ruitenbeek NJ, Adang C, O'Gorman L, Lee PY, Klein WM, van Engen-van Grunsven ACH, Schalken JA, Bervoets S, Verhaegh GW, van Herpen CML.   +10 more
europepmc   +2 more sources

ADCC

Frontiers in Immunology, 2023
In this short review, we summarized the results obtained with an assay to detect influenza virus-specific antibodies that mediate ADCC, which was developed and evaluated within the framework of the IMI-funded project “FLUCOP”. HA-specific ADCC mediating antibodies were detected in serum samples from children and adults pre- and post-vaccination with ...
de Vries, Rory D., Hoschler, Katja, Rimmelzwaan, Guus F.   +2 more
openaire   +1 more source

Primary pulmonary salivary gland-type tumors in cytopathology practice: A systematic review and meta-analysis. [PDF]

Cancer Cytopathol
Abstract Background Primary pulmonary salivary gland‐type tumors (PSGTs) are rare but clinically significant tumors that originate from the submucosal glands of the tracheobronchial tree. Cytologic samples taken during bronchoscopy are a key component of preoperative evaluation. However, cytologic diagnosis remains challenging because of the submucosal
Lagerstam H, Kalfert D, Kholová I.
europepmc   +2 more sources

Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies

eLife, 2021
A prerequisite for the design of an HIV vaccine that elicits protective antibodies is understanding the developmental pathways that result in desirable antibody features. The development of antibodies that mediate antibody-dependent cellular cytotoxicity
Laura E Doepker, Sonja Danon, Elias Harkins, Duncan K Ralph, Zak Yaffe, Meghan E Garrett, Amrit Dhar, Cassia Wagner, Megan M Stumpf, Dana Arenz, James A Williams, Walter Jaoko, Kishor Mandaliya, Kelly K Lee, Frederick A Matsen IV, Julie M Overbaugh   +15 more
doaj   +1 more source

Development of antibody-dependent cellular cytotoxicity in response to recombinant and live-attenuated herpes zoster vaccines

npj Vaccines, 2022
Zoster vaccines generate antibody responses against varicella-zoster virus (VZV). We compared antibody-dependent cell cytotoxicity (ADCC) elicited by zoster vaccine live (ZVL) and recombinant zoster vaccine (RZV).
Seong Yeon Park, Myron J. Levin, Jennifer Canniff, Michael Johnson, D. Scott Schmid, Adriana Weinberg   +5 more
doaj   +1 more source

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors

OncoImmunology, 2017
The use of monoclonal antibodies (mAb) for the diagnosis and treatment of malignancies is acquiring an increasing clinical importance, thanks to their specificity, efficacy and relative easiness of use. However, in the context of Epstein-Barr virus (EBV)-
Riccardo Turrini, Anna Merlo, Debora Martorelli, Damiana Antonia Faè, Roberta Sommaggio, Isabella Monia Montagner, Vito Barbieri, Oriano Marin, Paola Zanovello, Riccardo Dolcetti, Antonio Rosato   +10 more
doaj   +1 more source

Pre-existing infant antibody-dependent cellular cytotoxicity associates with reduced HIV-1 acquisition and lower morbidity

Cell Reports Medicine, 2021
Summary: In humans, pre-existing anti-HIV-1 neutralizing antibodies (nAbs) have not been associated with decreased HIV-1 acquisition. Here, we evaluate antibody-dependent cellular cytotoxicity (ADCC) present in pre-transmission infant and maternal plasma
Allison S. Thomas, Yvetane Moreau, Wenqing Jiang, John E. Isaac, Alexander Ewing, Laura F. White, Athena P. Kourtis, Manish Sagar   +7 more
doaj   +1 more source

Dynamic currency linkages between select emerging market economies: An empirical study

Cogent Economics & Finance, 2019
In this article, we examine the dynamic currency linkages for BRIS (Brazil, Russia, India and South Africa) and 15 other emerging market economies (EMEs) using weekly data from 2001 to 2018.
Arjun Mittal, Sanjay Sehgal, Anand Mittal   +2 more
doaj   +1 more source

Combination Strategies to Enhance Antitumor ADCC [PDF]

Immunotherapy, 2012
The clinical efficacy of monoclonal antibodies as cancer therapeutics is largely dependent upon their ability to target the tumor and induce a functional antitumor immune response. This two-step process of ADCC utilizes the response of innate immune cells to provide antitumor cytotoxicity triggered by the interaction of the Fc portion of the antibody ...
Holbrook E, Kohrt, Roch, Houot, Aurélien, Marabelle, Hearn Jay, Cho, Keren, Osman, Matthew, Goldstein, Ronald, Levy, Joshua, Brody   +7 more
openaire   +2 more sources