Results 11 to 20 of about 26,161 (209)

ADCC Assay Protocol

open access: yesBio-Protocol, 2014
Antibody-dependent cell-mediated cytotoxicity (ADCC) bridges innate and adaptive immunity, and it involves both humoral and cellular immune responses.
Vikram Srivastava   +5 more
doaj   +2 more sources

ADCC

open access: yesFrontiers in Immunology, 2023
In this short review, we summarized the results obtained with an assay to detect influenza virus-specific antibodies that mediate ADCC, which was developed and evaluated within the framework of the IMI-funded project “FLUCOP”. HA-specific ADCC mediating antibodies were detected in serum samples from children and adults pre- and post-vaccination with ...
de Vries, Rory D.   +2 more
openaire   +1 more source

Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies

open access: yeseLife, 2021
A prerequisite for the design of an HIV vaccine that elicits protective antibodies is understanding the developmental pathways that result in desirable antibody features. The development of antibodies that mediate antibody-dependent cellular cytotoxicity
Laura E Doepker   +15 more
doaj   +1 more source

Development of antibody-dependent cellular cytotoxicity in response to recombinant and live-attenuated herpes zoster vaccines

open access: yesnpj Vaccines, 2022
Zoster vaccines generate antibody responses against varicella-zoster virus (VZV). We compared antibody-dependent cell cytotoxicity (ADCC) elicited by zoster vaccine live (ZVL) and recombinant zoster vaccine (RZV).
Seong Yeon Park   +5 more
doaj   +1 more source

Pre-existing infant antibody-dependent cellular cytotoxicity associates with reduced HIV-1 acquisition and lower morbidity

open access: yesCell Reports Medicine, 2021
Summary: In humans, pre-existing anti-HIV-1 neutralizing antibodies (nAbs) have not been associated with decreased HIV-1 acquisition. Here, we evaluate antibody-dependent cellular cytotoxicity (ADCC) present in pre-transmission infant and maternal plasma
Allison S. Thomas   +7 more
doaj   +1 more source

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors

open access: yesOncoImmunology, 2017
The use of monoclonal antibodies (mAb) for the diagnosis and treatment of malignancies is acquiring an increasing clinical importance, thanks to their specificity, efficacy and relative easiness of use. However, in the context of Epstein-Barr virus (EBV)-
Riccardo Turrini   +10 more
doaj   +1 more source

Dynamic currency linkages between select emerging market economies: An empirical study

open access: yesCogent Economics & Finance, 2019
In this article, we examine the dynamic currency linkages for BRIS (Brazil, Russia, India and South Africa) and 15 other emerging market economies (EMEs) using weekly data from 2001 to 2018.
Arjun Mittal   +2 more
doaj   +1 more source

ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection

open access: yesPLoS Pathogens, 2021
Despite antibody-dependent cellular cytotoxicity (ADCC) responses being implicated in protection from HIV-1 infection, there is limited evidence that they control virus replication.
Dieter Mielke   +14 more
doaj   +2 more sources

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production

open access: yesOncoImmunology, 2017
Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC), based on the recognition of IgG-opsonized targets by the low-affinity receptor for IgG FcγRIIIA/CD16, represents one of the main mechanisms by which therapeutic antibodies
Cristina Capuano   +9 more
doaj   +1 more source

HIV-gp140-Specific Antibodies Generated From Indian Long-Term Non-Progressors Mediate Potent ADCC Activity and Effectively Lyse Reactivated HIV Reservoir

open access: yesFrontiers in Immunology, 2022
Strategies to reduce the human immunodeficiency virus (HIV) reservoir are urgently required. The antibody-dependent cellular cytotoxicity (ADCC)-mediating anti-HIV antibodies have shown an association with HIV control.
Jayshree R. Dhande   +2 more
doaj   +1 more source

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