Computerized Modeling of Adenosine Triphosphate, Adenosine Triarsenate and Adenosine Trivanadate [PDF]
Molecules, 2012 Computerized molecular models of adenosine triphosphate, adenosine tri-arsenate and adenosine trivanadate have been generated using the molecular mechanics technique. The analysis of structural parameters indicated that, at least theoretically, adenosine
Valter A. Nascimento +2 more
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Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy [PDF]
Korean Journal of Anesthesiology, 2020 Background Studies investigating the correlation between spinal adenosine A1 receptors and vincristine-induced peripheral neuropathy (VIPN) are limited.
Kyungmi Kim +3 more
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Polyphenol (-)-epigallocatechin gallate-induced cardioprotection may attenuate ischemia-reperfusion injury through adenosine receptor activation: a preliminary study [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundThe activation of guanine nucleotide binding protein-coupled receptors, such as adenosine receptor (ADR) and opioid receptor (OPR), protects the heart against ischemia and reperfusion injury. We hypothesized that ADR or OPR might be involved in
Sang Kwon Lee +7 more
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CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers
Frontiers in Immunology, 2020 CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the way for
Jerry B. Harvey +3 more
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Adenosine signaling: Optimal target for gastric cancer immunotherapy
Frontiers in Immunology, 2022 Gastric cancer (GC) is one of the most common malignancy and leading cause of cancer-related deaths worldwide. Due to asymptomatic or only nonspecific early symptoms, GC patients are usually in the advanced stage at first diagnosis and miss the best ...
Junqing Wang, Linyong Du, Xiangjian Chen
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Purinergic Regulation of Food and Fat Intakes in Broiler’s Central Nervous System [PDF]
Iranian Journal of Veterinary Medicine, 2021 BACKGROUND: Adenosine has many physiological roles in the brain, and in rodents, it changes food intake when applied centrally. OBJECTIVES: We investigated the effect of central injection of the purine molecule adenosine on both food and fat intakes in ...
Sahel Motaghi +3 more
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Caffeine in liver diseases: Pharmacology and toxicology
Frontiers in Pharmacology, 2022 We have previously shown that adenosine A1AR antagonists, adenosine A2aAR antagonists, and caffeine have significant inhibitory effects on the activation and proliferation of hepatic stellate cells in alcoholic liver fibrosis.
Liang Shan +10 more
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Adenosinergic Signaling as a Key Modulator of the Glioma Microenvironment and Reactive Astrocytes
Frontiers in Neuroscience, 2022 Astrocytes are numerous glial cells of the central nervous system (CNS) and play important roles in brain homeostasis. These cells can directly communicate with neurons by releasing gliotransmitters, such as adenosine triphosphate (ATP) and glutamate ...
Gabriela N. Debom +3 more
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Fast-Strain Encoded Cardiac Magnetic Resonance During Vasodilator Perfusion Stress Testing
Frontiers in Cardiovascular Medicine, 2021 Background: Cardiac magnetic resonance perfusion imaging during vasodilator stress is an established modality in patients with suspected and known coronary artery disease (CAD).Aim: This study aimed to evaluate the performance of fast-Strain-Encoded-MRI (
Henning Steen +10 more
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Frontiers in Cardiovascular Medicine, 2020 Reflex atrioventricular block is well-recorded although it is considered rare. Recent data suggests that it is less rare than has been supposed. It has been shown to occur in both vasovagal and carotid sinus reflexes.
Richard Sutton
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