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Computerized Modeling of Adenosine Triphosphate, Adenosine Triarsenate and Adenosine Trivanadate [PDF]

open access: yesMolecules, 2012
Computerized molecular models of adenosine triphosphate, adenosine tri-arsenate and adenosine trivanadate have been generated using the molecular mechanics technique. The analysis of structural parameters indicated that, at least theoretically, adenosine
Valter A. Nascimento   +2 more
doaj   +3 more sources

Purinergic Regulation of Food and Fat Intakes in Broiler’s Central Nervous System [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2021
BACKGROUND: Adenosine has many physiological roles in the brain, and in rodents, it changes food intake when applied centrally. OBJECTIVES: We investigated the effect of central injection of the purine molecule adenosine on both food and fat intakes in ...
Sahel Motaghi   +3 more
doaj   +1 more source

Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy [PDF]

open access: yesKorean Journal of Anesthesiology, 2020
Background Studies investigating the correlation between spinal adenosine A1 receptors and vincristine-induced peripheral neuropathy (VIPN) are limited.
Kyungmi Kim   +3 more
doaj   +1 more source

CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers

open access: yesFrontiers in Immunology, 2020
CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the way for
Jerry B. Harvey   +3 more
doaj   +1 more source

A Circadian Clock in the Retina Regulates Rod-Cone Gap Junction Coupling and Neuronal Light Responses via Activation of Adenosine A2A Receptors

open access: yesFrontiers in Cellular Neuroscience, 2021
Adenosine, a major neuromodulator in the central nervous system (CNS), is involved in a variety of regulatory functions such as the sleep/wake cycle.
Jiexin Cao   +2 more
doaj   +1 more source

Reduced Microvascular Blood Volume as a Driver of Coronary Microvascular Disease in Patients With Non-obstructive Coronary Artery Disease: Rationale and Design of the MICORDIS Study

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Ischemia with non-obstructive coronary arteries (INOCA) is part of the ischemic heart disease spectrum, and is particularly observed in women.
Caitlin E. M. Vink   +4 more
doaj   +1 more source

Polyphenol (-)-epigallocatechin gallate-induced cardioprotection may attenuate ischemia-reperfusion injury through adenosine receptor activation: a preliminary study [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundThe activation of guanine nucleotide binding protein-coupled receptors, such as adenosine receptor (ADR) and opioid receptor (OPR), protects the heart against ischemia and reperfusion injury. We hypothesized that ADR or OPR might be involved in
Sang Kwon Lee   +7 more
doaj   +1 more source

Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases [PDF]

open access: yesJournal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88, 2020
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate neurotransmitter release and neuronal plasticity. A large number of gene association studies have shown that common
arxiv   +1 more source

General anesthesia or conscious sedation in paroxysmal atrial fibrillation catheter ablation

open access: yesBiomedical Papers, 2021
Background. Catheter ablation of paroxysmal atrial fibrillation (AF) can be performed under general anesthesia or conscious sedation. The influence of type of anesthesiology care on procedural characteristics and ablation outcome in patients in whom ...
Ondrej Moravec   +10 more
doaj   +1 more source

The implications of alcohol mixed with energy drinks from medical and socio-legal standpoints

open access: yesFrontiers in Behavioral Neuroscience, 2022
Co-ingestion of energy drinks and alcohol has long been in practice and has been poorly regulated despite a growing body of literature of their potential negative health impacts.
Jessica Atef Nassef Sefen   +2 more
doaj   +1 more source

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