Results 1 to 10 of about 892,163 (354)

Ability of γδ T cells to modulate the Foxp3 T cell response is dependent on adenosine. [PDF]

, 2018
Whether γδ T cells inhibit or enhance the Foxp3 T cell response depends upon their activation status. The critical enhancing effector in the supernatant is adenosine.
Born, Willi K, Kaplan, Henry J, Liang, Dongchun, O'Brien, Rebecca L, Shao, Hui, Sun, Deming, Woo, Jeong-Im   +6 more
core   +9 more sources

Neuropathic pain: Mechanisms and therapeutic strategies

Frontiers in Cell and Developmental Biology, 2023
The physiopathology and neurotransmission of pain are of an owe inspiring complexity. Our ability to satisfactorily suppress neuropathic or other forms of chronic pain is limited.
Georg A. Petroianu, Lujain Aloum, Abdu Adem   +2 more
doaj   +1 more source

Recent advancements in the practice of neuroanaesthesia and neurocritical care: An update

Indian Journal of Anaesthesia, 2023
The practice of neuroanaesthesia has expanded significantly in recent years to keep up with various challenges posed in the perioperative care of patients for neurosurgical, interventional, neuroradiological, and diagnostic procedures.
Manikandan Sethuraman, Prasanna Udupi Bidkar, Ramamani Mariappan, Rajshree C Deopujari, Ponniah Vanamoorthy, Mayank Massand   +5 more
doaj   +1 more source

Contemporary notions on the role of 5'-nucleotidase in pregnancy

Russian Open Medical Journal, 2022
The review aimed at pooling together available information on 5'-nucleotidase – an enzyme hydrolyzing ribo- and deoxyribonucleoside-5'-monophosphates. The most important product of 5'-nucleotidase activity is adenosine.
Inna V. Dovzhikova, Irina A. Andrievskaya   +1 more
doaj   +1 more source

Multi‐Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing

Advanced Science, 2023
Bone injuries such as fractures are one major cause of morbidities worldwide. A considerable number of fractures suffer from delayed healing, and the unresolved acute pain may transition to chronic and maladaptive pain.
Yu‐Ru V. Shih, David Kingsley, Hunter Newman, Jiaul Hoque, Ankita Gupta, B. Duncan X. Lascelles, Shyni Varghese   +6 more
doaj   +1 more source

Effectiveness of metabolic therapy in patients with myocardial infarction and type 2 diabetes mellitus

Медицина неотложных состояний, 2023
Background. Patients diagnosed with an ST-elevation myocardial infarction and type 2 diabetes mellitus present a complex clinical scenario with an increased risk of adverse cardiovascular outcomes.
M.V. Bielinskyi, N.M. Seredyuk, S.V. Fedorov, A.S. Herashchenko, D.A. Volynskyi   +4 more
doaj   +1 more source

Adenosine Improves Mitochondrial Function and Biogenesis in Friedreich's Ataxia Fibroblasts Following L-Buthionine Sulfoximine-Induced Oxidative Stress

Biology, 2023
Adenosine is a nucleoside that is widely distributed in the central nervous system and acts as a central excitatory and inhibitory neurotransmitter in the brain.
Sze Yuen Lew, Nur Shahirah Mohd Hisam, Michael Weng Lok Phang, Syarifah Nur Syed Abdul Rahman, Rozaida Yuen Ying Poh, Siew Huah Lim, Mohd Amir Kamaruzzaman, Sze Chun Chau, Ka Chun Tsui, Lee Wei Lim, Kah Hui Wong   +10 more
doaj   +1 more source

Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice

Cells, 2021
Recently, the involvement of the nervous system in the pathology of allergic diseases has attracted increasing interest. However, the precise pathophysiological role of enteric neurons in food allergies has not been elucidated.
Tomoe Yashiro, Hanako Ogata, Syed Faisal Zaidi, Jaemin Lee, Shusaku Hayashi, Takeshi Yamamoto, Makoto Kadowaki   +6 more
doaj   +1 more source

Remote Conditioning by Rhythmic Compression of Limbs Ameliorated Myocardial Infarction by Downregulation of Inflammation via A2 Adenosine Receptors

Frontiers in Cardiovascular Medicine, 2022
BackgroundRemote ischemic conditioning (RIC) is a cardioprotective phenomenon, yet transient ischemia is not a requisite trigger for remote cardioprotection.
Senlei Xu, Senlei Xu, Renjun Gu, Xiangyu Bian, Xin Xu, Xuefeng Xia, Yuchen Liu, Chengjie Jia, Yihuang Gu, Hongru Zhang, Hongru Zhang   +10 more
doaj   +1 more source

Identification of Major Antioxidant Compounds from the Edible Mushroom Basidiomycetes-X (Echigoshirayukidake)

Frontiers in Bioscience-Elite, 2022
Basidiomycetes-X, of which Japanese vernacular name is Echigoshirayukidake, is a local speciality mushroom found and cultivated in Japan that has been distributed as a precious cuisine material or as a functional food with medicinal properties ...
Toshio Sakamoto, Zhenshi Li, Ayaka Nishida, Asako Kadokawa, Takayuki Yoshida, Naoki Wada, Seiichi Matsugo, Yutaka Nakamura, Shinji Sato, Tetsuya Konishi   +9 more
doaj   +1 more source