Results 121 to 130 of about 489,446 (226)

Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates With Progression of Human Myeloma

Molecular Medicine, 2016
Human myeloma cells express CD38 at high levels and grow in hypoxic niches inside the bone marrow. Myeloma cells respond to hypoxia with metabolic changes leading to aerobic glycolysis, thus reducing adenosine triphosphate (ATP) and increasing NAD+.
A. Horenstein, V. Quarona, D. Toscani, F. Costa, A. Chillemi, V. Pistoia, N. Giuliani, F. Malavasi   +7 more
semanticscholar   +1 more source

Automatic instrument for chemical processing to detect microorganism in biological samples by measuring light reactions [PDF]

, 1973
An automated apparatus is reported for sequentially assaying urine samples for the presence of bacterial adenosine triphosphate (ATP) that comprises a rotary table which carries a plurality of sample containing vials and automatically dispenses fluid ...
Chappelle, E. W., Colburn, M. E., Kelbaugh, B. N., Picciolo, G. L.   +3 more
core   +1 more source

Glutamate-induced depression of EPSP–spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors [PDF]

, 2010
The presence of high concentrations of glutamate in the extracellular fluid following brain trauma or ischaemia may contribute substantially to subsequent impairments of neuronal function.
Alici, Andersen, Baratte, Bazhenov, Behan, Benveniste, Bernard, Bernard, Brunedge, Canhão, Carlier, Cash, Clement, Connick, Costenla, Coulter, Cunha, Cunha, Cunha, Cunha, Dahl, Daoudal, Davies, de Mendonça, de Mendonça, de Mendonça, Englund, Ferguson, Fontinha, Forghani, Frenguelli, Frenguelli, Fujii, Fujii, Greiner, Heurteaux, Hoehn, Hülsmann, Jester, Jones, Kitagawa, Klishin, Kukley, Latini, Latini, Lau, Lee, Limbrick, Liu, Lopes, Macgregor, Manzoni, Moore, Nikbakht, Nishizawa, O’Kane, O’Kane, Pedata, Perez-Pinzon, Pugliese, Pugliese, Ribeiro, Schubert, Schurr, Sebastião, Sebastião, Sekino, Sperlagh, Stone, Stone, Szatkowski, Taube, Vizi, Von Lubitz, Wall, Wallis, Wirkner, Wirkner   +77 more
core   +1 more source

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

Cell Death and Disease, 2015
The NLR pyrin domain containing 3 (NLRP3) inflammasome is a major component of the innate immune system, but its mechanism of activation by a wide range of molecules remains largely unknown.
L. Baron, A. Gombault, Manoussa Fanny, B. Villeret, F. Savigny, N. Guillou, Corinne Panek, M. Bert, V. Lagente, F. Rassendren, N. Riteau, I. Couillin   +11 more
semanticscholar   +1 more source

Energy from food [PDF]

arXiv, 2017
Expressing the energy content of food as the heat energy released by its combustion is potentially misleading. Food is used to produce adenosine triphosphate (ATP). The free energy of conversion of ATP into adenosine diphosphate is used directly for processes such as muscular contraction, without the need for intermediate heat production. The number of
arxiv  

Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]

, 2013
During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Dunwiddie TV, Magnus J. E. Richardson, Mark J. Wall, Michael I. Kerr   +3 more
core   +1 more source

Protection Against Infarction Afforded by Preconditioning is Mediated by A1 Adenosine Receptors in Rabbit Heart

Circulation, 1991
BackgroundPreconditioning (5 minutes of ischemia followed by 10 minutes of recovery) renders the heart very resistant to infarction from subsequent ischemia. This study tests whether adenosine receptors might mediate preconditioning protection.
Guang S. Liu, J. Thornton, D. M. Van Winkle, A. Stanley, R. Olsson, J. Downey   +5 more
semanticscholar   +1 more source

The roles of adenosine and adenosine receptors in bone remodeling

Frontiers in Bioscience, 2011
Adenosine regulates a wide variety of physiological processes including heart rate, vasodilation and inflammation through the activation of specific cell surface adenosine receptors. In addition to these well-established roles of adenosine, recent genetic and pharmacological research has implicated adenosine as an important regulator in bone remodeling.
Bruce N. Cronstein, Wenjie He
openaire   +3 more sources

AMPK Regulation of Mouse Oocyte Meiotic Resumption in Vitro [PDF]

, 2006
We have previously shown that the adenosine analog 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR), an activator of AMP-activated protein kinase (AMPK), stimulates an increase in AMPK activity and induces meiotic resumption in mouse oocytes ...
Chang, Aimee S., Chen, Jing, Chi, Maggie M., Downs, Stephen M., Hardie, D. Grahame, Hudson, Emma R., Moley, Kelle H.   +6 more
core   +2 more sources

Incorporation of Adenosine and Adenosine Triphosphate into Rat Myocardium

Japanese Heart Journal, 1969
The isolated rat heart is perfused with adenosine-8-C14, or a mixture of ATP-8-C14 and ATP-γ-P32 of known isotope (C14/P32) ratio. The results indicate that any difference between the rate of incorporation of adenosine-C14 or ATP-C14 into myocardial nucleosides and nucleotides fraction did not show significance, and also that any difference of the C14 ...
Eizou Hattori, Motoomi Nakamura, Tadashi Miyazaki   +2 more
openaire   +4 more sources