Results 121 to 130 of about 892,163 (354)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

EMERGENCY TREATMENT OF SVT: ADENOSINE VERSUS VERAPAMIL

open access: yesJournal of University Medical & Dental College, 2017
: Introduction: Supraventricular tachycardia (SVT) is a common arrhythmia seen in critical care settings. After vagal maneuvers, adenosine 6 to 12 mg intravenous bolus is the initial drug of choice.
Naeem Asghar   +2 more
doaj  

Determination of nucleosides in Cordyceps sinensis and Ganoderma lucidum by high performance liquid chromatography method

open access: yesJournal of Pharmacy and Bioallied Sciences, 2015
Background: Nucleosides are supportive in the regulation and modulation of various physiological processes in body, they acts as precursors in nucleic acid synthesis, enhance immune response, help in absorption of iron and influence the metabolism of ...
Masood Shah Khan   +4 more
doaj   +1 more source

Temperoammonic stimulation depotentiates Schaffer collateral LTP via p38 MAPK downstream of adenosine A1 receptors [PDF]

open access: yes, 2019
We previously found that low-frequency stimulation of direct temperoammonic (TA) inputs to hippocampal area CA1 depotentiates previously established long-term potentiation in the Schaffer collateral (SC) pathway through complex signaling involving ...
Izumi, Yukitoshi, Zorumski, Charles F
core   +1 more source

An open-label, one-arm, dose-escalation study to evaluate safety and tolerability of extremely low frequency magnetic fields in acute ischemic stroke [PDF]

open access: yes, 2017
Extremely low frequency magnetic fields (ELF-MF) could be an alternative neuroprotective approach for ischemic stroke because preclinical studies have demonstrated their effects on the mechanisms underlying ischemic damage. The purpose of this open-label,
Apollonio, Francesca   +7 more
core   +2 more sources

Cryo‐EM of Rationally Designed Photosystem I Nanoassembly on Graphene Validates Orientation‐Driven Enhancement of Photocatalytic Performance

open access: yesAdvanced Functional Materials, EarlyView.
The first cryo‐EM visualization and quantification of oriented Photosystem I (PSI) on single‐layer graphene is reported. Domain‐specific covalent anchoring of PSI, with the reducing side of the biophotocatalyst toward graphene, promotes three‐fold higher anodic photocurrent generation compared to a randomly physisorbed counterpart. This approach allows
Miriam Izzo   +6 more
wiley   +1 more source

The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease.

open access: yesJournal of Caffeine and Adenosine Research, 2018
Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the IT15 gene that encodes for the huntingtin protein.
D. Blum   +7 more
semanticscholar   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Electrical Acupuncture Efficacy on Inflammatory Pain

open access: yes康复学报, 2018
Objective:To explore electrical acupuncture (EA) therapy effects on complete freund's adjuvant (CFA) induced inflammatory pain model rats.Methods:A total of 30 SD male rats were randomly divided into normal saline+Sham Electroacupuncture (NS+SE) group ...
Minghong SUI   +5 more
doaj  

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

open access: yesAdvanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna   +10 more
wiley   +1 more source

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