Results 121 to 130 of about 681,334 (361)
Coulomb Interaction as the Source of Muscle Force [PDF]
arXiv, 2007 Myosin motor is the machine, which performs mechanical work in the course of adenosine triphosphate molecule hydrolysis and myosin head conformations accompanying this process. For displacement of individual fragments of large molecule relative to each other to arise and work to be performed, force must be born inside protein.
arxiv
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang +9 more
wiley +1 more source
The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTO-FFR) Study. [PDF]
, 2016 AIMS: Adenosine administration is needed for the achievement of maximal hyperaemia fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa ratio registered during submaximal hyperaemia induced by non-ionic contrast ...
Amabile, N +5 more
core +1 more source
Pilot study of electrochemical reduction of selected nucleotides and double-stranded DNA at pristine micro-/ultrananocrystalline boron-doped diamond electrodes at very negative potentials [PDF]
Pristine polycrystalline boron-doped diamond electrodes (BDDEs) -- microcrystalline (B-MCDE) and ultrananocrystalline (B-UNCDE) were applied for the electrochemical reduction of several selected purine nucleotides -- Guanosine 5'-monophosphate (GMP), 2'-Deoxyguanosine 5'-monophosphate (dGMP), Adenosine 5'-monophosphate (AMP), Adenosine 5'-diphosphate ...
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.To suppress uveal melanoma metastasis (UM), the GSH‐responsive polymer named NP@Oxa/Criz has been successfully prepared. NP@Oxa/Criz selectively accumulates in UM tumors, targeting HGF/c‐Met Axis to undermine the stemness and metastasis of UM while triggering immunogenic cell death through DAMPs release to boost anti‐tumor immunity.
Hui Tao +8 more
wiley +1 more source
Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency. [PDF]
, 2015 Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is characterized by impaired T-, B- and NK-cell function. Affected children, in addition to early onset of infections, manifest non-immunologic symptoms including pulmonary ...
Candotti, Fabio +6 more
core +2 more sources
Frontiers in Immunology, 2018 Our increasing appreciation of adenosine as an endogenous signaling molecule that terminates inflammation has generated excitement regarding the potential to target adenosine receptors (ARs) in the treatment of multiple sclerosis (MS), a disease of ...
Skanda Rajasundaram
doaj +1 more source
Kinetic Analysis of Protein Assembly on the Basis of the Center Manifold around the Critical Point [PDF]
arXiv, 2015 Protein assembly plays an important role in the regulation of biological systems. The cytoskeleton assembly activity is provided by the binding cofactors GTP (guanidine triphosphate) or ATP(adenosine triphosphate) to monomeric protein, and is initiated by assembling the monomeric proteins.
arxiv
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Automatic instrument for chemical processing to detect microorganism in biological samples by measuring light reactions [PDF]
, 1973 An automated apparatus is reported for sequentially assaying urine samples for the presence of bacterial adenosine triphosphate (ATP) that comprises a rotary table which carries a plurality of sample containing vials and automatically dispenses fluid ...
Chappelle, E. W. +3 more
core +1 more source