Results 131 to 140 of about 124,204 (359)
The role of the neuromodulator adenosine in alcohols actions. [PDF]
, 1997 The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core
Characterisation of the adenosine A1 receptor in Saccharomyces cerevisiae
The FASEB Journal, 2008 Different ligands for G protein‐coupled receptors can induce unique receptor conformations, leading to differing profiles of G protein coupling. Given that S. cerevisiae expression systems are useful tools for studying the coupling of GPCRs to individual G protein pathways, experiments were undertaken to investigate whether different pharmacological ...
Greg Stewart +4 more
openaire +2 more sources
British Journal of Haematology, EarlyView.Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez +34 more
wiley +1 more source
Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia. [PDF]
, 2012 Paroxysmal nonkinesigenic dyskinesia (PNKD) is an autosomal dominant episodic movement disorder. Patients have episodes that last 1 to 4 hours and are precipitated by alcohol, coffee, and stress.
Edwards, Robert H +10 more
core +2 more sources
Frontiers in PharmacologyThe synapses between parallel fibers and Purkinje cells play a pivotal role in cerebellar function. They are intricately governed by a variety of presynaptic receptors, notably by type 4 metabotropic glutamate (mGlu4) receptors and type 1 adenosine (A1 ...
Simon Bossi +2 more
doaj +1 more source
Journal of Neuroscience, 2006 Adenosine is arguably the most potent and widespread presynaptic modulator in the CNS, yet adenosine receptor signal transduction pathways remain unresolved.
Tyson B. Brust +3 more
semanticscholar +1 more source
European Journal of Clinical Investigation, EarlyView.This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano +3 more
wiley +1 more source
Role of adenosine in the antiepileptic effects of deep brain stimulation
Frontiers in Cellular Neuroscience, 2014 Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy remain elusive.
Maisa eMiranda +14 more
doaj +1 more source
A1 and A2 adenosine receptors in rabbit cortical collecting tubule cells. Modulation of hormone-stimulated cAMP. [PDF]
, 1987 Lois J. Arend +3 more
openalex +1 more source
Anxiolytic properties of A1 adenosine receptor PAMs
Oncotarget, 2016 Anxiolytic properties of A1 adenosine receptor ...
VINCENZI, Fabrizio +2 more
openaire +4 more sources