Results 141 to 150 of about 68,176 (222)

Prediction of 90 day mortality in elderly patients with acute HF from e‐health records using artificial intelligence

ESC Heart Failure, Volume 12, Issue 3, Page 2200-2209, June 2025.
Abstract Aims Mortality risk after hospitalization for heart failure (HF) is high, especially in the first 90 days. This study aimed to construct a model automatically predicting 90 day post‐discharge mortality using electronic health record (EHR) data 48 h after admission and artificial intelligence. Methods All HF‐related admissions from 2015 to 2020
Joconde Weller, Johann Gutton, Guillaume Hocquet, Leïla Pellet, Marie‐José Aroulanda, Amélie Bruandet, Didier Theis, Fabio Boudis, Romain Cador, Pierre Zweigenbaum, Anne Buronfosse, Pascal de Groote, Michel Komajda   +12 more
wiley   +1 more source

Role of Adenosine A1 Receptor in Sleep Deprivation-Induced Neuroinflammation: Insights on Rapid Eye Movement Sleep and Fear Extinction Memory Recall in Rats. [PDF]

Cureus
Thondala B, Chauhan G, Pawar H, Ray K, Sharma M, Yadav N, Kumar S, Kishore K, Panjwani U.   +8 more
europepmc   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

British Journal of Pharmacology, Volume 182, Issue 12, Page 2803-2820, June 2025.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange, Tobias Brunn, Charlotte Vetter, Konstantin Bloch, Nora Vedder, Chiel van Geffen, Philipp Gercke, Saeed Kolahian   +7 more
wiley   +1 more source

Discovery of Highly Potent Adenosine A₁ Receptor Agonists: Targeting Positron Emission Tomography Probes. [PDF]

ACS Chem Neurosci, 2021
Guo M, Bakhoda A, Gao ZG, Ramsey JM, Li Y, O'Conor KA, Kelleher AC, Eisenberg SM, Kang Y, Yan X, Javdan C, Fowler JS, Rice KC, Hooker JM, Jacobson KA, Kim SW, Volkow ND.   +16 more
europepmc   +1 more source

Plant genetic transformation: achievements, current status and future prospects

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2034-2058, June 2025.
Summary Regeneration represents a fundamental biological process wherein an organism's tissues or organs repair and replace themselves following damage or environmental stress. In plant systems, injured tree branches can regenerate adventitious buds and develop new crowns through propagation techniques like cuttings and canopy pruning, while transgenic
Peilin Wang, Huan Si, Chenhui Li, Zhongping Xu, Huiming Guo, Shuangxia Jin, Hongmei Cheng   +6 more
wiley   +1 more source

From blood flow to organ function: The physiology of autoregulatory dynamics

Experimental Physiology, EarlyView.
Niels‐Henrik Holstein‐Rathlou, Donald J. Marsh   +1 more
wiley   +1 more source

Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
Inhibition of focal adhesion kinase autophosphorylation (Y397) in adipocytes is associated with reduced glucose uptake, likely via the disruptions of Arp2/3 and Rac1 activity, leading to impaired cytoskeletal remodeling and consequential impairment of GLUT4 translocation. B = binding, GTP = GTP‐loading, P = phosphorylation.
Franziska Kopietz, Mathis Neuhaus, Andrea Borreguero‐Muñoz, Dmytro Kryvokhyzha, Karin G. Stenkula   +4 more
wiley   +1 more source

Ligand-Directed Labeling of the Adenosine A₁ Receptor in Living Cells. [PDF]

J Med Chem
Comeo E, Goulding J, Lin CY, Groenen M, Woolard J, Kindon ND, Harwood CR, Platt S, Briddon SJ, Kilpatrick LE, Scammells PJ, Hill SJ, Kellam B.   +12 more
europepmc   +1 more source

Activation of Adenosine A₁ Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist. [PDF]

Antioxidants (Basel), 2021
Ruan L, Li G, Zhao W, Meng H, Zheng Q, Wang J.   +5 more
europepmc   +1 more source

β-Lapachone Exerts Hypnotic Effects via Adenosine A₁ Receptor in Mice. [PDF]

Biomol Ther (Seoul)
Lee DH, Jee HJ, Jung YS.
europepmc   +1 more source