Results 141 to 150 of about 31,304 (262)

Neuroanesthesia and Intensive Care Isoflurane tolerance against focal cerebral ischemia is attenuated by adenosine A1 receptor antagonists [PDF]

, 2006
Yanhong Liu, Lize Xiong, Shaoyang Chen, Qiang Wang   +3 more
openalex   +1 more source

Spatiotemporally Controlled Tumor Photodynamic/Immunotherapy Therapy Based on Upconversion Hybrid Nanosystem

Advanced Science, Volume 13, Issue 7, 3 February 2026.
PURH is constructed by a five‐layer upconversion nanoparticle (UCNP) surface coated with mesoporous silica, which encapsulates rose bengal (RB) within the mesoporous channels. Additionally, CpG oligonucleotides (CpG ODN) is linked to the surface, followed by the surface functionalization of hyaluronic acid (HA). This spatiotemporally controllable smart
Fang Wang, Wenfei Xu, Yuechen Liu, Shuxuan Zhu, Wenjing Liu, Shuhui Bo, Hong Sun, Bei Liu, Zhaogang Sun, Hongqian Chu   +9 more
wiley   +1 more source

Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy. [PDF]

Pharmaceuticals (Basel), 2021
Persike DS, Puccinelli RPA, Fernandes MJDS.   +2 more
europepmc   +1 more source

Targeting the SIRT1‐NAT10‐GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane‐Induced Cognitive Impairment in Aging

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The study reveals that NAT10 enhances GABABR1 mRNA stability via ac4A modification, leading to excessive inhibitory synaptic activation. In aged rats, sevoflurane contributes to cognitive impairment by inhibiting Sirt1 and neuronal autophagy, which subsequently disrupts energy metabolism.
Xin Xie, Wei Du, Yanmei Zhang, Xiaomin Zhang   +3 more
wiley   +1 more source

Adenosine A₁ receptor agonism protection mechanism in intestinal ischemia/reperfusion injury via activation of PI3K/Akt signaling. [PDF]

Exp Ther Med, 2023
Xu Q, Mao Z, Yun Y.
europepmc   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Adenosine A_2A Receptors Shut Down Adenosine A₁ Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation. [PDF]

Biomolecules, 2023
Lopes CR, Gonçalves FQ, Olaio S, Tomé AR, Cunha RA, Lopes JP.   +5 more
europepmc   +1 more source

Artemisia selengensis Leaves, a Vegetable Waste: LC‐MS‐Based Chemical Profiling, Ultrasound‐Assisted DES Extraction, and Xanthine Oxidase Inhibitory Activity

eFood, Volume 7, Issue 1, February 2026.
This study focused on Artemisia selengensis leaves (ASL), a discarded agricultural waste. 72 compounds were identified by UPLC‐Q‐TOF‐MS. “Green” extraction with DES was optimized, and ASL's XO—inhibition was explored, presenting new ways for waste utilization. ABSTRACT Artemisia selengensis is a medicinal and edible plant, whose tender stems are widely
Lixia Li, Mingqiu Shan, Rongli Qiu, Sheng Yu, Ting Geng, Li Zhang, Xinli Liang, Baoxiang Wu, Facheng Zhang   +8 more
wiley   +1 more source

Static Stretching Acutely Reduces the Ergogenic Effects of Caffeine on Sprint Performance but Not Maximal Ball Velocity in Football Players

European Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT This study aimed to investigate the independent and combined effects of caffeine and static stretching (SS) on maximal ball velocity and 30‐m sprint performance. Sixteen male amateur football players performed 30‐m sprint and an instep kicking ball velocity test under six conditions.
Refik Çabuk, İzzet İslamoğlu, Onur Demirarar, Faruk Albay, Yıldırım Kayacan   +4 more
wiley   +1 more source

A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A₁ Receptor Using an Electrophilic Covalent Probe. [PDF]

ACS Chem Biol, 2022
Beerkens BLH, Koç Ç, Liu R, Florea BI, Le Dévédec SE, Heitman LH, IJzerman AP, van der Es D.   +7 more
europepmc   +1 more source