Results 161 to 170 of about 127,904 (323)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure [PDF]

open access: yes, 2015
15BACKGROUND: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved ...

core  

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson   +6 more
wiley   +1 more source

Discovery and Structure-Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists. [PDF]

open access: yesJ Med Chem, 2022
Preti B   +9 more
europepmc   +1 more source

Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells

open access: yesCell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.
ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros   +3 more
wiley   +1 more source

Fructose-1,6-Bisphosphate Reduces Chronic Constriction Injury Neuropathic Pain in Mice by Targeting Dorsal Root Ganglia Nociceptive Neuron Activation

open access: yesPharmaceuticals
Background/Objectives: Fructose-1,6-bisphosphate (FBP) is an intermediate product of the glycolytic pathway with analgesic effect in acute inflammatory pain model via the production of adenosine.
Amanda Martins Dionisio   +9 more
doaj   +1 more source

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