Results 161 to 170 of about 31,304 (262)

Molecular mechanisms of plant NLR activation and signalling

open access: yesThe Plant Journal, Volume 125, Issue 3, February 2026.
SUMMARY Plants rely on NLRs (nucleotide‐binding leucine‐rich repeat receptors) to recognise effector proteins secreted by pathogens into plant cells and to deliver disease resistance. Plant NLRs are broadly characterised by their N‐terminal domains, which include the TIR (Toll/interleukin‐1 receptor) and the CC (coiled‐coil) domains.
Natsumi Maruta   +3 more
wiley   +1 more source

Chronic treatment with adenosine A1 receptor antagonist promotes neurogenesis and improves outcome after cerebral ischemia. [PDF]

open access: yesJ Cereb Blood Flow Metab
Ardaya M   +14 more
europepmc   +1 more source

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai   +5 more
wiley   +1 more source

Positive allosteric mechanisms of adenosine A<sub>1</sub> receptor-mediated analgesia. [PDF]

open access: yesNature, 2021
Draper-Joyce CJ   +23 more
europepmc   +1 more source

Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists

open access: hybrid, 2023
Pierre Matricon   +10 more
openalex   +2 more sources

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