Results 31 to 40 of about 127,904 (323)

Adenosine A1 receptor-mediated protection of mouse hippocampal synaptic transmission against oxygen and/or glucose deprivation: a comparative study.

Journal of Neurophysiology, 2019
Adenosine receptors are widely expressed in the brain and adenosine is a key bioactive substance for neuroprotection. Here, we clarify systematically the role of adenosine A1 receptors during a range of timescales and conditions when a significant amount
M. Kawamura, D. N. Ruskin, S. Masino
semanticscholar   +1 more source

A Role for Adenosine A1 Receptors in GABA and NMDA-Receptor Mediated Modulation of Dopamine Release: Studies Using Fast Cyclic Voltammetry

Sensors, 2008
In the striatum many neurotransmitters including GABA, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. Dopamine release in the striatum is regulated by a number of pre- and postsynaptic receptors
Carmel O’Neill, John J. O’Connor   +1 more
doaj   +1 more source

Repeated topical paeoniflorin attenuates postoperative pain and accelerates cutaneous fibroblast proliferation in mice

Journal of Pharmacological Sciences, 2023
This study investigated whether the repeated topical paeoniflorin inhibits postoperative pain in mice. An incision of the plantar skin and underlying muscle of the hind paw elicits acute postoperative pain.
Tsugunobu Andoh, Momoka Goto
doaj   +1 more source

Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain

Arquivos de Neuro-Psiquiatria, 2018
Neuropathic pain is a chronic pain condition caused by damage or dysfunction of the central or peripheral nervous system. Electroacupuncture (EA) has an antinociceptive effect on neuropathic pain, which is partially due to inhibiting astrocyte activation
Ming-xiao Zhang, Qinxue Dai, Dongdong Liang, Dan Li, Sijia Chen, Shuangdong Chen, Kun-yuan Han, Luping Huang, Junlu Wang   +8 more
semanticscholar   +1 more source

Adenosine signaling in airways: Toward a promising antiasthmatic approach [PDF]

, 2013
Adenosine participates to asthma physiopathology by signaling through more than just one receptor subtype. Defining the role of each receptor is complicated by evidence that often results obtained on rodents do not coincide with human studies, but what ...
CICALA, CARLA, IALENTI, ARMANDO
core   +1 more source

Involvement of adenosine signaling pathway in migraine pathophysiology: a systematic review of preclinical studies

The Journal of Headache and Pain, 2022
Background Adenosine is a purinergic signaling molecule with a wide range of physiological functions including anti- and pronociceptive properties. Adenosine receptors are expressed in the trigeminovascular system, and adenosine receptor antagonist ...
Janu Thuraiaiyah, Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi, Messoud Ashina   +3 more
doaj   +1 more source

The Role of Adenosine Receptor Agonists in Regulation of Hematopoiesis

Molecules, 2011
The review summarizes data evaluating the role of adenosine receptor signaling in murine hematopoietic functions. The studies carried out utilized either non-selective activation of adenosine receptors induced by elevation of extracellular adenosine or ...
Michal Hofer, Milan Pospisil, Zuzana Hoferova, Lenka Weiterova   +3 more
doaj   +1 more source

Glutamate-induced depression of EPSP–spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors [PDF]

, 2010
The presence of high concentrations of glutamate in the extracellular fluid following brain trauma or ischaemia may contribute substantially to subsequent impairments of neuronal function.
Alici, Andersen, Baratte, Bazhenov, Behan, Benveniste, Bernard, Bernard, Brunedge, Canhão, Carlier, Cash, Clement, Connick, Costenla, Coulter, Cunha, Cunha, Cunha, Cunha, Dahl, Daoudal, Davies, de Mendonça, de Mendonça, de Mendonça, Englund, Ferguson, Fontinha, Forghani, Frenguelli, Frenguelli, Fujii, Fujii, Greiner, Heurteaux, Hoehn, Hülsmann, Jester, Jones, Kitagawa, Klishin, Kukley, Latini, Latini, Lau, Lee, Limbrick, Liu, Lopes, Macgregor, Manzoni, Moore, Nikbakht, Nishizawa, O’Kane, O’Kane, Pedata, Perez-Pinzon, Pugliese, Pugliese, Ribeiro, Schubert, Schurr, Sebastião, Sebastião, Sekino, Sperlagh, Stone, Stone, Szatkowski, Taube, Vizi, Von Lubitz, Wall, Wallis, Wirkner, Wirkner   +77 more
core   +1 more source

Impaired Inhibitory Function of Presynaptic A1-Adenosine Receptors in SHR Mesenteric Arteries

Journal of Pharmacological Sciences, 2013
In hypertension, vascular reactivity alterations have been attributed to numerous factors, including higher sympathetic innervation/adenosine. This study examined the modulation of adenosine receptors on vascular sympathetic nerves and their putative ...
Carolina Rocha-Pereira, Silvia Magdalena Arribas, Paula Fresco, Maria Carmen González, Jorge Gonçalves, Carmen Diniz   +5 more
doaj   +1 more source

The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium

Frontiers in Pharmacology, 2022
Cannabidiol (CBD), the most extensively studied non-intoxicating phytocannabinoid, has been attracting a lot of interest worldwide owing to its numerous beneficial effects.
Gabor Viczjan, Gabor Viczjan, Anna Szilagyi, Barbara Takacs, Ignac Ovari, Reka Szekeres, Vera Tarjanyi, Tamas Erdei, Vanda Teleki, Judit Zsuga, Zoltan Szilvassy, Bela Juhasz, Balazs Varga, Rudolf Gesztelyi   +13 more
doaj   +1 more source