Results 61 to 70 of about 127,904 (323)

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Adenosine Receptor Agonists Modulate Visceral Hyperalgesia in the Rat

Gut and Liver, 2008
Background/Aims: Adenosine is an endogenous modulator of nociception. Its role in visceral nociception, particularly in visceral hyperalgesia, has not been studied.
doaj   +1 more source

Evidence for coordinated induction and repression of ecto-5'-nucleotidase (CD73) and the A2a adenosine receptor in a human B cell line [PDF]

, 2003
In the human B cell line P493-6 two mitogenic signals, the EpsteinBarr virus nuclear antigen 2 (EBNA2) and myc, can be independently regulated by means of an estrogen receptor fusion construct or an inducible expression vector, respectively.
Burgemeister R., LeHir M., Narravula S., Savic V., Spychala J., Xaus J., Zimmermann H.   +6 more
core   +1 more source

Adenosine A1 Receptor-Mediated Activation of Phospholipase C in Cultured Astrocytes Depends on the Level of Receptor Expression

Journal of Neuroscience, 1997
Adenosine A1 receptors induce an inhibition of adenylyl cyclase via G-proteins of the Gi/o family. In addition, simultaneous stimulation of A1 receptors and of receptor-mediated activation of phospholipase C (PLC) results in a synergistic potentiation of
K. Biber, K. Klotz, M. Berger, P. Gebicke-Härter, D. van Calker   +4 more
semanticscholar   +1 more source

Recent Advances in Reactive Microdroplets for Clean Water and Energy

Advanced Materials, EarlyView.
Reactive microdroplets enable precise and sustainable chemistry at small scales. This review explores their role as confined reactors and dynamic interfaces for synthesizing functional materials, fuels, and microdevices. It offers a critical perspective on how droplet‐based platforms can drive next‐generation technologies in clean energy, environmental
Qiuyun Lu, Boubakar Sanogo, Tanay Kumar, Ben Bin Xu, Xuehua Zhang   +4 more
wiley   +1 more source

Targeting Adenosine A2b Receptor Promotes Penile Rehabilitation of Refractory Erectile Dysfunction

Advanced Science
The mechanisms of adenosine and specific adenosine receptor subtypes in promoting penile rehabilitation remain unclear. Single‐cell RNA sequencing of human corpus cavernosum,  adenosine deaminase (ADA) and adenosine receptors knock‐out mice (ADA−/−, A1−/−
Yang Xiong, Feng Qin, Shanzun Wei, Xingliang Yang, Jun Li, Changjing Wu, Fuxun Zhang, Jiuhong Yuan   +7 more
doaj   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source

Synergistic Effects of Adenosine A2A Antagonist and L-DOPA on Rotational Behaviors in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Mouse Model

Journal of Pharmacological Sciences, 2007
In this study, we examined the combination effects of L-DOPA and adenosine receptor antagonists on rotational behaviors in a hemi-Parkinsonian mouse model induced by unilateral 6-hydroxydopamine (6-OHDA) injection. The adenosine A2A antagonist SCH-58261,
Takahiro Matsuya, Kazuhiro Takuma, Kosuke Sato, Makoto Asai, Yoshihiro Murakami, Sosuke Miyoshi, Akihiro Noda, Taku Nagai, Hiroyuki Mizoguchi, Shintaro Nishimura, Kiyofumi Yamada   +10 more
doaj   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Electroacupuncture Pretreatment Prevents Cognitive Impairment Induced by Cerebral Ischemia–Reperfusion via Adenosine A1 Receptors in Rats

Frontiers in Aging Neuroscience, 2021
A previous study has demonstrated that pretreatment with electroacupuncture (EA) induces rapid tolerance to focal cerebral ischemia. In the present study, we investigated whether adenosine receptor 1 (A1 R) is involved in EA pretreatment-induced ...
Yiyi Shi, Qinxue Dai, Binbin Ji, Luping Huang, Xiuxiu Zhuang, Yunchang Mo, Junlu Wang   +6 more
doaj   +1 more source