Results 81 to 90 of about 127,904 (323)
Journal of Biological Chemistry, 2004 The Gi-linked adenosine A1 receptor has been shown to mediate anti-inflammatory actions, possibly via modulation of the transcription factor nuclear factor-κB (NFκB).
Andrew M. F. Liu, Y. Wong
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Cannabidiol (CBD) is approved as an adjunctive treatment of seizures associated with Dravet syndrome, Lennox–Gastaut Syndrome, and tuberous sclerosis. Its therapeutic and adverse effects are thought to arise, at least partly, from a pharmacokinetic interaction with clobazam, another anti‐seizure medication (ASM).
Andriy A. Gorbenko +7 more
wiley +1 more source
Purinergic mechanosensory transduction and visceral pain [PDF]
, 2009 In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain.
Burnstock, G
core +3 more sources
European Journal of Heart Failure, EarlyView.This study investigated the prognostic value of residual congestion phenotypes at discharge in acute heart failure. Patients with intravascular residual congestion had better diuretic responses and shorter hospital stays than those with tissue/combined residual congestion, but worse outcomes than decongested patients.
Daan C.H. Ceelen +15 more
wiley +1 more source
Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome
Epileptic Disorders, EarlyView.Abstract Objective The ketogenic diet (KD) is the standard treatment for glucose transporter type 1 deficiency syndrome (GLUT1‐DS), typically yielding seizure reduction and cognitive/motor gains. However, a small subset of patients shows limited or no clinical benefit.
Raffaele Falsaperla +8 more
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine. [PDF]
PLoS ONE, 2015 Despite considerable evidence that glia can release modulators to influence the excitability of neighbouring neurons, the importance of gliotransmission for the operation of neural networks and in shaping behaviour remains controversial.
David Acton, Gareth B Miles
doaj +1 more source
Design and synthesis of new fluorescent probes for A2B adenosine receptor. [PDF]
, 2014 Adenosine is an endogenous purine nucleoside that plays a key role in numerous important physiological functions through interactions with specific cell-surface G-protein-coupled receptors (GPCRs), which are classified into four subtypes, namely A1, A2A,
MORETTI, ELEONORA
core
The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components [PDF]
, 2014 G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner.
Agnati, Luigi F +12 more
core +4 more sources
Journal of Biological Chemistry, 1998 The antagonistic interactions between adenosine A1 and dopamine D1 receptors were studied in a mouse Ltk− cell line stably cotransfected with human adenosine A1 receptor and dopamine D1 receptor cDNAs.
S. Ferré +7 more
semanticscholar +1 more source