Results 91 to 100 of about 54,436 (239)

SIGNIFICANCE OF ADENOSINE DEAMINASE SERUM CONCENTRATIONS IN THE DIAGNOSIS OF EXTRA-PULMONARY TUBERCULOSIS [PDF]

Journal of IMAB, 2011
Extra pulmonary tuberculosis (EPTB) is a growing problem worldwide. Due to the nature of the disease, the diversity of clinical pictures as well as its minor epidemiological importance, the diagnosis is difficult and often late.In addition to standard TB
Stevanovic G,, Pelemis M,, Pavlovic M,, Lavadinovic L,, Dakic Z,, Milosevic I,, Milosevic B.   +6 more
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Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients

مجلة بغداد للعلوم, 2010
Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy.
Baghdad Science Journal
doaj   +1 more source

A Case of Aseptic Meningitis Presenting With Widespread Non‐Dermatomal Neuropathic Pain

Journal of General and Family Medicine, Volume 27, Issue 2, March 2026.
ABSTRACT Aseptic meningitis occasionally causes neuropathic pain in a dermatomal distribution, but widespread non‐dermatomal pain is extremely rare. We report a case of a 62‐year‐old man with ulcerative colitis who developed neuropathic pain involving the head, trunk, and limbs.
Jun Komoda
wiley   +1 more source

RNA editing signature during myeloid leukemia cell differentiation [PDF]

, 2017
Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated.
A Athanasiadis, A Gallo, AS Shifera, BE Wulff, BJ Liddicoat, BL Bass, C Cenci, C Sundstrom, C Trapnell, C Trapnell, D Laxminarayana, E Picardi, E Picardi, G Camilli, H Aberle, H Li, JB Patterson, JC Hartner, JH Bahn, JM Desterro, Justin M. Thomas, K Nishikura, L Bazak, L Chen, M D'Antonio, M Daigneault, M Higuchi, M Vogler, MA Zipeto, MA Zipeto, N Mannion, N Paz-Yaacov, Q Jiang, Q Wang, Q Wang, R Marcucci, R XuFeng, RA Steinman, RJ Orlowski, S Tomaselli, S Tomaselli, T Hwang, TD Wu, TR Dawson, W Slotkin, Y Li, Y Pinto, YJ Crow, YS Baek   +48 more
core   +2 more sources

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

Molecular evidence of adenosine deaminase linking adenosine A2A receptor and CD26 proteins [PDF]

, 2018
Adenosine is an endogenous purine nucleoside that acts in all living systems as a homeostatic network regulator through many pathways, which are adenosine receptor (AR)-dependent and -independent. From a metabolic point of view, adenosine deaminase (ADA)
Akiyama, Aliyari Serej, Angers, Antonioli, Anz, Arin, Arin, Baerts, Baker, Beckenkamp, Beckers, Bertheleme, Beyazit, Blackburn, Blanco, Borea, Borea, Bottari, Bourgaux, Briddon, Brown, Buckley, Canals, Carpenter, Casadó, Casadó, Casadó, Casadó-Anguera, Casanova, Cekic, Chang, Chapple, Chen, Cheng, Cigler, Ciruela, Ciruela, Ciruela, Congreve, Cooper, Copley, Copley, Corbel, Cordero, Cortés, Cronstein, Cunha, Da Silva, Deriziotis, Desrosiers, Doré, Du, Eltzschig, Fan, Franco, Franco, Franco, Fredholm, Fredholm, Gandia, Gile, Ginés, Golias, Gonzalez-Gronow, Gorrell, Gracia, Gracia, Gracia, Gracia, Grosskopf, Havre, Havre, Hawryluk, He, Herrera, Hino, Horwitz, Huang, Ingwersen, Jaakola, Jacobson, Jazayeri, Jeffery, Jeffery, Jeffery, Kameoka, Kanno, Khalili, Khare, Kim, Kimura, Kinoshita, Klemann, Kutryb-Zajac, Lambeir, Larrinaga, Lazarus, Lebon, Lebon, Lee, Leiva, Liu, Loeser, Lohse, Lu, Machleidt, Maiuolo, Maleki, Mandapathil, Martinez-Navio, Martinez-Navio, Martín, Meli, Mo, Moreno, Moreno, Moretti, Mortier, Namba, Naval-Macabuhay, Navarro, Niu, Ohta, Pacheco, Petschnigg, Richard, Ruiz, Saraon, Sarrió, Saura, Segala, Sharma, Shaw, Sheth, Shrivastava, Songok, Souza Vdo, Stockwell, Sun, Sun, Sun, Torvinen, Tsuji, Turel, Vidi, Viñals, Wagner, Wang, Weihofen, Welch, Welihinda, Wilson, Xin, Xu, Yin, Yu, Yu, Zavialov, Zavialov, Zhang, Zhong, Zhong   +161 more
core   +1 more source

Inhibiting ADAR1‐Mediated Excessive Epigenetic A‐to‐I RNA Editing Improves the Immune Microenvironment and Increases Sensitivity to Immunotherapy in Lung Adenocarcinoma

MedComm, Volume 7, Issue 3, March 2026.
This study investigated the potential of inhibiting ADAR1 which catalyzed excessive A‐to‐I RNA editing as a therapeutic strategy to augment the effectiveness of immunotherapy in LUAD. Mouse models demonstrated that inhibiting ADAR1 in tumor cells significantly improved the immune microenvironment by increasing PD‐L1 expression and CD8+ T‐cell ...
Sihui Wang, Sufei Zheng, Chengming Liu, Chaoqi Zhang, Xinfeng Wang, Zhanyu Wang, Yan Wang, Xiaoli Feng, Qi Xue, Nan Sun, Jie He   +10 more
wiley   +1 more source

Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]

, 2014
Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R, Gschweng, Eric H, Kohn, Donald B, Lill, Georgia R   +3 more
core   +1 more source

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Adenosine deaminase (ADA) level in tubercular pleural effusion

Lung India, 2008
Study objective : To study the value of adenosine deaminase level in tuber-cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical ...
Verma S, Dubey A, Singh P, Tewerson S, Sharma Devashish   +4 more
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