Results 81 to 90 of about 215,850 (301)

A adenosinadesaminase. Uma enzima pluridisciplinar.

Acta Médica Portuguesa, 1991
Adenosine deaminase is an enzyme that actively participates in the metabolism of the adenine nucleotides. It catalyzes the irreversible hydrolytic deamination of deoxyadenosine and adenosine with the production of deoxyinosine and inosine respectively ...
J G da Cunha
doaj   +1 more source

From WGS to gels: Development and testing of PCR primers targeting toxic Digitalis in support of food safety

Applications in Plant Sciences, EarlyView.
Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Elizabeth Sage Hunter, Sydnee Fo, Robert Literman, Richard H. Uva, Jennifer L. Wolny, Sara M. Handy   +5 more
wiley   +1 more source

Clinical Significance of Serum Adenosine Deaminase Levels in Breast Cancer Patients

Journal of Islamic International Medical College, 2021
Objective: To compare serum adenosine deaminase (ADA) levels in untreated and treated cases of breast cancer patients. Study Design: It was an Analytical, observational study. Place and Duration of study: The study was carried out in the Department
Wajahat Ullah Khan, Amena Rahim, Kenza Mobeen, Muhammad Afzal, Abdul Khaliq Naveed
doaj  

Secreted bacterial adenosine deaminase is an evolutionary precursor of adenosine deaminase growth factor [PDF]

Molecular Biology and Evolution, 2018
Adenosine deaminases (ADAs) play a pivotal role in regulating the level of adenosine, an important signaling molecule that controls a variety of cellular responses. Two distinct ADAs, ADA1 and adenosine deaminase growth factor (ADGF aka ADA2), are known.
Anton V. Zavialov, Maksym Skaldin, Maksym Skaldin, Andrey V. Zavialov, Minna Tuittila   +4 more
openaire   +4 more sources

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Non-specific biological markers as a screening test for diagnostic of extrapulmonary tuberculosis [PDF]

Archives of Biological Sciences, 2012
Serum concentrations of adenosine deaminase were determined in 223 febrile patients. In 62, we discovered extrapulmonary tuberculosis. Serum levels of immunoglobulin G were monitored in 287 febrile patients, and 68 had extra-pulmonary tuberculosis ...
Stevanovic G., Pelemis M., Pelemis S., Pavlovic M.   +3 more
doaj   +1 more source

Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses*

Journal of Biological Chemistry, 2016
Adenosine deaminases acting on double-stranded RNA (ADARs) catalyze the deamination of adenosine (A) to produce inosine (I) in double-stranded (ds) RNA structures, a process known as A-to-I RNA editing.
C. George, Gokul Ramaswami, J. B. Li, C. E. Samuel   +3 more
semanticscholar   +1 more source

Clinical Significance of Gut Microbiota Community Types for Long‐term Response to Fecal Microbiota Transplantation in Patients with Psoriatic Arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Fecal microbiota transplantation (FMT) holds promises as a beneficial supplement to methotrexate in patients with psoriatic arthritis (PsA). We therefore investigated how gut bacterial signatures in patients and donor strain engraftment associated with long‐term response to FMT.
Panpan Qin, Maja S. Kragsnaes, Dorte K. Holm, Hans Christian Horn, Anna Christine Nilsson, Jens Kjeldsen, Karsten Kristiansen, Torkell Ellingsen   +7 more
wiley   +1 more source

Paediatric rare diseases: Can large language models assist off‐label prescribing?

British Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effectiveness and reliability of large language models (LLMs) in retrieving and synthesizing biomedical information to support off‐label drug prescribing in paediatric rare diseases, and to compare their performance with human‐authored references in terms of scientific rationale, adverse events and drug interactions.
Anna Flamigni, Giulia Zamagni, Gilda Paternuosto, Anna Arbo   +3 more
wiley   +1 more source

Top‐Down Coercive Mechanisms and the Major Transitions in Evolution

BioEssays, EarlyView.
For the Major Transitions in Evolution we present two frameworks for the process of group formation from independent entities. 1) The received view, which focuses on cooperative bottom‐up mechanisms. 2) Our top‐down coercion framework, which considers both coercive and cooperative mechanisms.
Javier Suárez, Adrian Stencel, Isobel Ronai   +2 more
wiley   +1 more source