Results 191 to 200 of about 803,750 (296)

Special Issue "Adenosine Receptors in Health and Disease". [PDF]

Int J Mol Sci
Vlajkovic SM.
europepmc   +1 more source

Spontaneous Adenosine and Dopamine Cotransmission in the Caudate-Putamen Is Regulated by Adenosine Receptors. [PDF]

ACS Chem Neurosci, 2021
Borgus JR, Wang Y, DiScenza DJ, Venton BJ.   +3 more
europepmc   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Ligand-directed covalent labelling of adenosine receptors. [PDF]

Purinergic Signal
Li CK, Gregory KJ, Jörg M.
europepmc   +1 more source

Adenosine, Adenosine Receptors and Neurohumoral Syncope: From Molecular Basis to Personalized Treatment. [PDF]

Biomedicines, 2022
Guieu R, Degioanni C, Fromonot J, De Maria L, Ruf J, Deharo JC, Brignole M.   +6 more
europepmc   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Synthetic Small-Molecule Ligands Targeted to Adenosine Receptors: Is There Potential Towards Ischemic Heart Disease? [PDF]

Cells
Xu Q, Opoku YN, Authi KS, Cilibrizzi A.
europepmc   +1 more source

Adenosine receptors: Emerging non-opioids targets for pain medications. [PDF]

Neurobiol Pain, 2022
Jung SM, Peyton L, Essa H, Choi DS.
europepmc   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

From empirical screening to lipid trolling: the evolution of extrahelical allosteric modulators of A₁ and A₃ adenosine receptors. [PDF]

Med Chem Res
Pavan M, Kurma SH, Oliva P, Broughton DP, Gao ZG, Auchampach JA, Jacobson KA.   +6 more
europepmc   +1 more source