Results 181 to 190 of about 803,750 (296)

Adenosine receptors and acute kidney injury: perspectives for future therapy. [PDF]

Purinergic Signal
Wissmann IB, Coelho RCD, Baseggio L, Cardoso AM.   +3 more
europepmc   +1 more source

Adenosine receptors differentially mediate enteric glial cell death induced by Clostridioides difficile Toxins A and B. [PDF]

Front Immunol, 2022
Costa DVS, Shin JH, Goldbeck SM, Bolick DT, Mesquita FS, Loureiro AV, Rodrigues-Jesus MJ, Brito GAC, Warren CA.   +8 more
europepmc   +1 more source

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

Advanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang, Yong Xiao, Jiangtao Luo, Xiao Yang, Yayun Yang, Qihang Wu, Chenxin Yu, Zhihao Zhou, Xiaoqing Si, Jiansen Miao, Yiting Tu, Qichen Lu, Boreng Qian, Xiangyang Wang, Jiake Xu, Changcan Shi, Haiming Jin   +16 more
wiley   +1 more source

Mitochondrial Localization and Function of Adenosine Receptors. [PDF]

Int J Biol Sci
Sánchez-Melgar A, Vultaggio-Poma V, Falzoni S, Fructuoso C, Albasanz JL, Di Virgilio F, Martín M.   +6 more
europepmc   +1 more source

Guanosine modulates K⁺ membrane currents in SH-SY5Y cells: involvement of adenosine receptors. [PDF]

Pflugers Arch, 2022
Gambino G, Giglia G, Gallo D, Scordino M, Giardina C, Zuccarini M, Di Iorio P, Giuliani P, Ciruela F, Ferraro G, Mudò G, Sardo P, Di Liberto V.   +12 more
europepmc   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Computational discovery of natural medicines targeting adenosine receptors for metabolic diseases. [PDF]

Front Pharmacol
Wang P, Xu Z, Deng Y, Yuan H, Wu Y, Jiang J, Lyu Z, Li Z.   +7 more
europepmc   +1 more source

Role of cardiac β₁-adrenergic and A₁-adenosine receptors in severe arrhythmias related to Parkinson's disease. [PDF]

Clinics (Sao Paulo), 2023
Menezes-Rodrigues FS, de Oliveira MP, Araújo EA, Ferraz HB, Finsterer J, Olszewer E, Taha MO, Scorza CA, Caricati-Neto A, Scorza FA.   +9 more
europepmc   +1 more source

Adenosine; adenosine A2b receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Targeted Perturbation of Mitochondrial Energy Metabolism via Thermoelectric Nanoflowers for Enhanced Cuproptosis Echoed With Immunotherapy

Advanced Science, EarlyView.
We fabricated a thermoelectric nanomedicine to disrupt the ATP energy supply for the copper transporter ATP7B, thereby enhancing cuproptosis and achieving synergistic immunotherapy for anti‐tumor purposes. The fabricated TBCT NFs can efficiently disrupt the electron transport chain function via superoxide‐induced NADH oxidation, leading to ATP ...
Haoyang Du, Chao Xu, Hao Wang, Bo Peng, Peng Liu, Wei Gao, Tao Ye, Xinyuan Yu, Ying Shi, Jiaxin Liu, Tiancong Zhao, Bin Sun, Piaoping Yang, Manjie Zhang   +13 more
wiley   +1 more source