Results 161 to 170 of about 271,223 (294)

Adenosine Receptors

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011
openaire   +2 more sources

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Adenosine Receptors Expression in Human Retina and Choroid with Age-related Macular Degeneration. [PDF]

J Ophthalmic Vis Res, 2023
Goebel CP, Song YS, Zaitoun IS, Wang S, Potter HAD, Sorenson CM, Sheibani N.   +6 more
europepmc   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Adenosine receptors as emerging therapeutic targets for diabetic kidney disease. [PDF]

Kidney Res Clin Pract, 2022
Pak ES, Cha JJ, Cha DR, Kanasaki K, Ha H.   +4 more
europepmc   +1 more source

Recent Advances and Challenges in Ammonia‐Hydrogen Energy Conversion

Advanced Science, EarlyView.
This work summarizes the latest progress of various catalytic methods in ammonia‐hydrogen energy conversion. The challenges and outlook of ammonia‐hydrogen energy conversion system are also emphasized. This work expects to build a blueprint of renewable and efficient ammonia‐hydrogen energy conversion systems under mild conditions.
Menghao Lv, Runchao Qin, Jianshuo Chen, Kaiwen Yang, Jianwei Lu, Weiwei Lei, Yifu Yu   +6 more
wiley   +1 more source

Molecular Simulations and Drug Discovery of Adenosine Receptors. [PDF]

Molecules, 2022
Wang J, Bhattarai A, Do HN, Akhter S, Miao Y.   +4 more
europepmc   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

Advanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi, Kateryna Andriienkova, Tetyana Goldanova, Ezgi Antmen, Thibaut Soubrie, Nihal Engin Vrana   +5 more
wiley   +1 more source

Adenosine Receptors in Neuroinflammation and Neurodegeneration. [PDF]

Cells
Salmaso V, Menin S, Moro S, Spalluto G, Federico S.   +4 more
europepmc   +1 more source

Update on the recent development of allosteric modulators for adenosine receptors and their therapeutic applications. [PDF]

Front Pharmacol, 2022
Pasquini S, Contri C, Cappello M, Borea PA, Varani K, Vincenzi F.   +5 more
europepmc   +1 more source