The sheep conceptus modulates proteome profiles in caruncular endometrium during early pregnancy [PDF]
This project was funded by NHS Grampian R&D project number RG05/019Peer ...
Al-Gubory, Kaïs +2 more
core +2 more sources
Identification of liver protein targets modified by tienilic acid metabolites using a two-dimensional Western blot-mass spectrometry approach [PDF]
International audienceA combined approach based on two-dimensional electrophoresis-immuno-blotting and nanoliquid chromatography coupled on-line with electrospray ionization mass spectrometry (nLC-MS/MS) was used to identify proteins modified by a ...
Dansette, Patrick, +2 more
core +2 more sources
In Silico Discovery of Candidate Drugs against Covid-19
Previous studies reported that Angiotensin converting enzyme 2 (ACE2) is the main cell receptor of SARS-CoV and SARS-CoV-2. It plays a key role in the access of the virus into the cell to produce the final infection.
Claudia Cava +2 more
doaj +1 more source
Insights into the regulation of DMSP synthesis in the diatom Thalassiosira pseudonana through APR activity, proteomics and gene expression analyses on cells acclimating to changes in salinity, light and nitrogen [PDF]
Despite the importance of dimethylsulphoniopropionate (DMSP) in the global sulphur cycle and climate regulation, the biological pathways underpinning its synthesis in marine phytoplankton remain poorly understood.
A Koprivova +61 more
core +3 more sources
Alexandrium is a neurotoxin-producing dinoflagellate genus resulting in paralytic shellfish poisonings around the world. However, little is known about the toxin biosynthesis mechanism in Alexandrium. This study compared protein profiles of A.
Da-Zhi Wang +3 more
doaj +1 more source
Specific immune priming in the invasive ctenophore Mnemiopsis leidyi [PDF]
Specific immune priming enables an induced immune response upon repeated pathogen encounter. As a functional analogue to vertebrate immune memory, such adaptive plasticity has been described, for instance, in insects and crustaceans. However, towards the
Eva E. R. Philipp +9 more
core +1 more source
Association network analysis identifies enzymatic components of gut microbiota that significantly differ between colorectal cancer patients and healthy controls [PDF]
The human gut microbiota plays a major role in maintaining human health and was recently recognized as a promising target for disease prevention and treatment.
Dongmei Ai +4 more
doaj +2 more sources
337 Targeting metabolic and epigenetic programs to re-sensitize glioblastoma to chemotherapy
OBJECTIVES/GOALS: Treatment options for glioblastoma (GBM) are limited. Prognosis remains dismal, with an 18 month on average survival rate following diagnosis due to treatment resistance and disease recurrence. The goal of this project is to investigate
Emma Rowland +5 more
doaj +1 more source
Somatic embryogenesis is the process by which bipolar structures with no vascular connection with the surrounding tissue are formed from a single or a group of vegetative cells, and in conifers it can be divided into five different steps: initiation ...
Ander Castander-Olarieta +9 more
doaj +1 more source
Investigations on the microbial catabolism of the organic sulfur compounds TDP and DTDP in H16 employing DNA microarrays [PDF]
In this study, we have investigated the transcriptome of Ralstonia eutropha H16 during cultivation with gluconate in presence of 3,3'-thiodipropionic acid (TDP) or 3,3'-dithiodipropionic acid (DTDP) during biosynthesis of poly(3-hydroxybutyrate-co-3 ...
Katja Peplinski +4 more
core +1 more source

