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Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines
Vaccines, 2020 Ever since the discovery of vaccines, many deadly diseases have been contained worldwide, ultimately culminating in the eradication of smallpox and polio, which represented significant medical achievements in human health.
Suresh K Mittal +2 more
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Comprehensive genome editing and signaling pathway engineering evolve potent and safe adenoviral producer cell [PDF]
Communications BiologyDramatic attention has been drawn to adenovirus as a vehicle for vaccine and cancer therapy, due to the capabilities of annihilating tumor cells and stimulating host immune response.
Zhe Deng +9 more
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Proceedings, 2023 A large amount of research has established that honey has potent antibacterial activity. However, the sensitivity of infection-causing viral species to honey has been scarcely studied.
Aysha F. Alagha +3 more
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Adenoviruses in lymphocytes of the human gastro-intestinal tract. [PDF]
PLoS ONE, 2011 Persistent adenoviral shedding in stools is known to occur past convalescence following acute adenoviral infections. We wished to establish the frequency with which adenoviruses may colonize the gut in normal human subjects.The presence of adenoviral DNA
Soumitra Roy +5 more
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A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation. [PDF]
PLoS Pathogens, 2013 Adenoviral replication depends on viral as well as cellular proteins. However, little is known about cellular proteins promoting adenoviral replication.
Wilhelm Ching +8 more
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Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines
Frontiers in Immunology, 2020 Adenoviral vectors are a safe and potently immunogenic vaccine delivery platform. Non-replicating Ad vectors possess several attributes which make them attractive vaccines for infectious disease, including their capacity for high titer growth, ease of ...
Lynda Coughlan
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Adenovirus as a Vector and Oncolytic Virus
Current Issues in Molecular Biology, 2023 Adenoviral vectors, both oncolytic viruses and gene delivery vectors, are among the earliest approved and commercialised vectors for gene therapy. Adenoviruses have high cytotoxicity and immunogenicity. Therefore, lentiviruses or adeno-associated viruses
Wataru Matsunaga, Akinobu Gotoh
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PREVENTION OF ADENOVIRAL EYE INFECTION - REVIEW
Sanamed, 2017 Epidemic viral conjunctivitis caused by adenovirus is the most common infectious conjunctivitis. The exact incidence of adenoviral conjunctivitis is still poorly known, but there are two well-defined adenoviral keratoconjunctivitis clinical syndromes ...
Katarina Mirjane Janicijevic +6 more
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Role of Adenoviruses in Cancer Therapy
Frontiers in Oncology, 2022 Cancer is one of the leading causes of death in the world, which is the second after heart diseases. Adenoviruses (Ads) have become the promise of new therapeutic strategy for cancer treatment.
Sintayehu Tsegaye Tseha +1 more
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Immunology of Adenoviral Vectors in Cancer Therapy
Molecular Therapy: Methods & Clinical Development, 2019 Adenoviruses are a commonly utilized virus for gene therapy platforms worldwide. Since adenovirus components are characterized as highly immunogenic, their immunogenicity inhibits the widespread use of adenoviral vectors to treat genetic disorders ...
Amanda Rosewell Shaw, Masataka Suzuki
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