Results 21 to 30 of about 70,698 (266)
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Genes and Diseases, 2017 With rapid advances in understanding molecular pathogenesis of human diseases in the era of genome sciences and systems biology, it is anticipated that increasing numbers of therapeutic genes or targets will become available for targeted therapies ...
Cody S. Lee +21 more
doaj +1 more source
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Frontiers in OphthalmologyPurposeAlthough it is often reported that adenovirus is the most common etiology for infectious conjunctivitis, a recent multi-center clinical study found that adenovirus was confirmed by polymerase chain reaction in only 16% of cases presenting with ...
Andrew T.E. Hartwick +10 more
doaj +1 more source
Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer
Journal for ImmunoTherapy of Cancer, 2020 Background Adenoviral vectors emerged as important platforms for cancer immunotherapy. Vaccination with adenoviral vectors is promising in this respect, however, their specific mechanisms of action are not fully understood.
Paul Klenerman +12 more
doaj +1 more source
Altering the Ad5 packaging domain affects the maturation of the Ad particles [PDF]
, 2011 We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Alba Fernández, Raúl +23 more
core +2 more sources
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Детские инфекции (Москва), 2017 In recent years, the number of adenoviral epidemic keratoconjunctivitis (EKC) cases in a neonatal intensive care unit (NICU) has increased, which is primarily due to the establishment of an ophthalmologic service in these institutions, and the increase ...
I. B. Astasheva
doaj +1 more source
Interleukin-encoding adenoviral vectors as genetic adjuvant for vaccination against retroviral infection. [PDF]
PLoS ONE, 2013 Interleukins (IL) are cytokines with stimulatory and modulatory functions in the immune system. In this study, we have chosen interleukins which are involved in the enhancement of TH2 responses and B cell functions to analyze their potential to improve a
Inga Ohs +4 more
doaj +1 more source
Adenoviral Infections in Pediatric Liver Transplant Recipients [PDF]
, 1987 Over a 51/2-year period, 22 of 262 children receiving liver transplants developed adenoviral infections. Five had adenoviral hepatitis in the allograft, caused by serotype 5.
Todo, S +8 more
core +1 more source