Results 11 to 20 of about 70,698 (266)

Progress in Adenoviral Capsid-Display Vaccines

open access: yesBiomedicines, 2018
Adenoviral vectored vaccines against infectious diseases are currently in clinical trials due to their capacity to induce potent antigen-specific B- and T-cell immune responses. Heterologous prime-boost vaccination with adenoviral vector and, for example,
Marija Vujadinovic, Jort Vellinga
doaj   +2 more sources

Construction and application of adenoviral vectors

open access: yesMolecular Therapy: Nucleic Acids, 2023
Adenoviral vectors have been widely used as vaccine candidates or potential vaccine candidates against infectious diseases due to the convenience of genome manipulation, their ability to accommodate large exogenous gene fragments, easy access of ...
Hongbo Zhang   +3 more
doaj   +2 more sources

Pathogenesis and management of adenoviral keratoconjunctivitis

open access: yesInfection and Drug Resistance, 2018
DeGaulle I Chigbu, Bisant A Labib Pennsylvania College of Optometry, Salus University, Elkins Park, PA, USA Abstract: Human adenovirus (HAdV) is a ubiquitous virus that infects the mucosa of the eye.
Chigbu DI, Labib BA
doaj   +1 more source

Adenoviral Keratoconjunctivitis

open access: yesSultan Qaboos University Medical Journal, 2007
Acute epibulbar infections in humans are one of the most frequently diagnosed eye diseases. The majority of these are thought to be caused by the adenovirus.
Alexander Bialasiewicz
doaj   +3 more sources

Development of novel vaccine vectors: Chimpanzee adenoviral vectors

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Adenoviral vector has been employed as one of the most efficient means against infectious diseases and cancer. It can be genetically modified and armed with foreign antigens to elicit specific antibody responses and T cell responses in hosts as well as ...
Jingao Guo   +2 more
doaj   +2 more sources

Squirrelpox and adenoviral PCR and serology dataset

open access: yes, 2019
Squirrelpox and adenoviral PCR and serology ...
Julian Chantrey (70799)
core   +4 more sources

Tropism-modification strategies for targeted gene delivery using adenoviral vectors [PDF]

open access: yes, 2010
Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ...
Coughlan, L.   +20 more
core   +1 more source

Adenoviral Producer Cells [PDF]

open access: yesViruses, 2010
Adenovirus (Ad) vectors, in particular those of the serotype 5, are highly attractive for a wide range of gene therapy, vaccine and virotherapy applications (as discussed in further detail in this issue). Wild type Ad5 virus can replicate in numerous tissue types but to use Ad vectors for therapeutic purposes the viral genome requires modification.
Kovesdi, Imre, Hedley, Susan J.
openaire   +3 more sources

Construction and characterization of an adenoviral vector encoding human bone morphogenetic protein-2

open access: yesJournal of International Medical Research, 2020
Objectives Construction of adenoviral vectors can be complicated and time-consuming. The aim of this study was to construct an adenoviral vector expressing human bone morphogenetic protein 2 (BMP-2).
Liangquan Peng   +8 more
doaj   +1 more source

Adenoviral Vectors: Potential as Anti-HBV Vaccines and Therapeutics

open access: yes, 2022
Adenoviral vaccines have been at the front line in the fight against pandemics caused by viral infections such as Ebola and the coronavirus disease 2019.
Tasneem Farhad   +7 more
core   +1 more source

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