Results 21 to 30 of about 35,275 (163)

Construction and characterization of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus capsid proteins of Indian vaccine strain, O/IND/R2/75 [PDF]

open access: yesVeterinary World, 2015
Aim: Generation of recombinant human adenovirus type 5 expressing foot-and-mouth disease virus (FMDV) capsid protein genes along with full-length 2B, 3B and 3Cpro and its characterization.
Ramesh Kumar   +2 more
doaj   +1 more source

Molecular evolution of human species D adenoviruses [PDF]

open access: yesInfection, Genetics and Evolution, 2011
Adenoviruses are medium-sized double stranded DNA viruses that infect vertebrates. Human adenoviruses cause an array of diseases. Currently there are 56 human adenovirus types recognized and characterized within seven species (A-G). Of those types, a majority belongs to species D.
Christopher M, Robinson   +4 more
openaire   +2 more sources

Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa

open access: yesEmerging Infectious Diseases, 2006
Human sera from the United States, Thailand, and sub-Saharan Africa and chimpanzee sera were tested for neutralizing antibodies to 3 chimpanzee adenoviruses.
Zhiquan Xiang   +7 more
doaj   +1 more source

Chimpanzee Adenoviruses Are Related to Four Subgenera of Human Adenoviruses

open access: yesIntervirology, 1989
Nine adenovirus strains isolated from chimpanzees were studied with regard to their relatedness to each other and to human adenovirus prototypes by neutralization and hemagglutination inhibition. The strains belonged to six serotypes, and all of them were clearly related to, but not identical to human adenoviruses of subgenus A, B, C, or E respectively.
R, Wigand, M, Mauss, T, Adrian
openaire   +2 more sources

Chimpanzee adenoviral vectors as vaccines – challenges to move the technology into the fast lane

open access: yesExpert Review of Vaccines, 2017
Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have been extensively evaluated as genetic vaccines. These vectors share desirable properties with human adenoviruses like the broad tissue tropism and the ease of large-
Alessandra Vitelli   +5 more
doaj   +1 more source

Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression

open access: yesMolecular Therapy: Oncolytics, 2020
Neuroblastoma (NB) is a primary malignant tumor of the peripheral sympathetic nervous system. High-risk NB is characterized by MYCN amplification and human telomerase reverse transcriptase (hTERT) rearrangement, contributing to hTERT activation and a ...
Terutaka Tanimoto   +9 more
doaj   +1 more source

Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells. [PDF]

open access: yesPLoS Pathogens, 2018
Following repeated encounters with adenoviruses most of us develop robust humoral and cellular immune responses that are thought to act together to combat ongoing and subsequent infections.
Thi Thu Phuong Tran   +7 more
doaj   +1 more source

Pyrogenicity of human adenoviruses

open access: yesJournal of General Virology, 2000
High doses (>1·56×107 p.f.u.) of purified preparations of human adenovirus types 3, 5 and 8 exhibited definite pyrogenic activity when injected intravenously into rabbits. Complete pyrogenic tolerance was obtained not only with homologous types but also with heterologous types of adenovirus.
openaire   +2 more sources

Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells

open access: yesJournal for ImmunoTherapy of Cancer, 2018
Background Oncolytic viruses are currently experiencing accelerated development in several laboratories worldwide, with some forty-seven clinical trials currently recruiting.
Janet Lei   +11 more
doaj   +1 more source

Adenoviruses in lymphocytes of the human gastro-intestinal tract. [PDF]

open access: yesPLoS ONE, 2011
Persistent adenoviral shedding in stools is known to occur past convalescence following acute adenoviral infections. We wished to establish the frequency with which adenoviruses may colonize the gut in normal human subjects.The presence of adenoviral DNA
Soumitra Roy   +5 more
doaj   +1 more source

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