The Journal of Physiology, EarlyView.Abstract figure legend Modelling β‐adrenergic stimulation in sympathetically remodelled ventricular substrates. Myocardial infarction could result in sympathetic remodelling in ventricular tissues, which affects arrhythmia dynamics. However sympathetic remodelling is challenging to control experimentally; therefore we created an ionic model that ...
Kelly Zhang +3 more
wiley +1 more source
HD Physiology Project-Japanese efforts to promote multilevel integrative systems biology and physiome research. [PDF]
, 2017 The HD Physiology Project is a Japanese research consortium that aimed to develop methods and a computational platform in which physiological and pathological information can be described in high-level definitions across multiple scales of time and size.
for HD physiology project investigators +3 more
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Regulation of Adenylyl Cyclases by a Region Outside the Minimally Functional Cytoplasmic Domains [PDF]
, 2002 Carole A. Parent +2 more
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Potential health benefits of cold‐water immersion: the central role of PGC‐1α
The Journal of Physiology, EarlyView.Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer +2 more
wiley +1 more source
A Real-Time, Fluorescence-Based Assay for Measuring µ-Opioid Receptor Modulation of Adenylyl Cyclase Activity in Chinese Hamster Ovary Cells [PDF]
, 2013 Alisa Knapman +3 more
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Molecular and biochemical characterization of the bicarbonate-sensing soluble adenylyl cyclase from a bony fish, the rainbow troutOncorhynchus mykiss [PDF]
, 2021 Cristina Salmerón +9 more
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Lifestyle implications of the paradox and management of oxidative stress in sperm
The Journal of Physiology, EarlyView.Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané +6 more
wiley +1 more source
Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans. [PDF]
, 2019 cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and biochemical tools suggest that cGMP is spatiotemporally regulated in multiple sensory modalities ...
Ali, Nebat +22 more
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Tissue Transglutaminase Directly Regulates Adenylyl Cyclase Resulting in Enhanced cAMP-response Element-binding Protein (CREB) Activation [PDF]
, 2003 Janusz Tucholski, Gail V.W. Johnson
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Hypercapnia Effects on Lung Function
Comprehensive Physiology, Volume 16, Issue 1, February 2026.CO2 is a signaling molecule that disrupts alveolar fluid clearance and ion transport, impairs alveolar repair, and promotes mitochondrial and endoplasmic reticulum dysfunction. It suppresses innate immunity, host defense, and inflammation, while increasing airway contractility.
Seungseo Choi +2 more
wiley +1 more source