Results 41 to 50 of about 52,241 (196)

The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration

Frontiers in Cellular Neuroscience, 2014
During brain development, radial glial cells possess an apico-basal polarity and are coupled by adherens junctions to an F-actin belt. To elucidate the role of the actin, we conditionally deleted the key component α-E-catenin in the developing cerebral ...
Marie-Theres eSchmid, Franziska eWeinandy, Michaela eWilsch-Bräuninger, Wieland B eHuttner, Silvia eCappello, Silvia eCappello, Magdalena eGötz, Magdalena eGötz   +7 more
doaj   +1 more source

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. [PDF]

, 2016
Heart of Glass (HEG1), a transmembrane receptor, and Rasip1, an endothelial-specific Rap1-binding protein, are both essential for cardiovascular development.
de Kreuk, Bart-Jan, Gingras, Alexandre R, Gingras, Anne-Claude, Ginsberg, Mark H, Knight, James Dr, Liu, Jian J   +5 more
core   +2 more sources

p120 catenin is required for the stress response in Drosophila [PDF]

, 2013
p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila ...
Bauer, Christin, Stefanatos, Rhoda K., Vidal, Marcos   +2 more
core   +7 more sources

Loss of Endothelial Barrier Function in the Inflammatory Setting: Indication for a Cytokine-Mediated Post-Transcriptional Mechanism by Virtue of Upregulation of miRNAs miR-29a-3p, miR-29b-3p, and miR-155-5p

Cells, 2021
Dysfunction of the endothelial barrier plays a central role in the pathogenesis of both acute and chronic inflammatory processes such as sepsis or atherosclerosis.
Daniel Maucher, Birte Schmidt, Julia Schumann   +2 more
doaj   +1 more source

Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions

, 2013
Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
core   +1 more source

Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)

EvoDevo, 2019
The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal adhesions ...
Jennyfer M. Mitchell, Scott A. Nichols
doaj   +1 more source

Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies [PDF]

, 1992
We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments.
Johnson, Ross G., Laird, Dale W., Meyer, Rita A., Revel, Jean-Paul   +3 more
core   +2 more sources

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]

, 2017
Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo, Ciccia, Francesco, Cypers, Heleen, Di Benedetto, Paola, Elewaut, Dirk, Fasano, Alessio, Gabrielli, Armando, Guggino, Giuliana, Luchetti, Michele Maria, Milling, Simon, Rizzo, Aroldo, Saieva, Laura, Stampone, Tommaso, Triolo, Giovanni   +13 more
core   +2 more sources

Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. [PDF]

, 2020
Polarized distribution of organelles and molecules inside a cell is vital for a range of cellular processes and its loss is frequently encountered in disease.
Choi, Julie, Ear, Jason, Ghassemian, Majid, Ghosh, Pradipta, Kufareva, Irina, Rajapakse, Navin, Saklecha, Anokhi   +6 more
core  

Complex polarity: building multicellular tissues through apical membrane traffic [PDF]

, 2016
The formation of distinct subdomains of the cell surface is crucial for multicellular organism development. The most striking example of this is apical-basal polarization.
Adams, Allaire, Altschuler, Ang, Aranda, Assemat, Bai, Baker, Balda, Balklava, Bedzhov, Benton, Betschinger, Blankenship, Boehlke, Bryant, Bryant, Bryant, Bulgakova, Butty, Campbell, Cancino, Chen, Chiba, Colley, Denef, Devenport, Dhekne, Eaton, Elias, Feldman, Ferrari, Fletcher, Galvez-Santisteban, Gamblin, Gangar, Gao, Gao, Gassama-Diagne, Georgiou, Gillard, Goldstein, Grawe, Graybill, Hammer, Hao, Hariharan, Harris, Harris, Harris, Hehnly, Hehnly, Hung, Hurd, Hurov, Hutterer, Hyenne, Izumi, Izumi, Joberty, Johnson, Kemphues, Klebes, Klinkert, Klose, Krahn, Kroschewski, Kumar, Kumichel, Kusakabe, Langevin, Leibfried, Lerner, Li, Li, Li, Lin, Lin, Ling, Liu, Lock, Lu, Macara, Martin-Belmonte, McGill, Melendez, Menut, Michaux, Moberg, Morais-de-Sa, Morrison, Mrozowska, Muller, Musch, Nakayama, Nakayama, Nakayama, Neisch, Ozdamar, Parsons, Pellikka, Pinal, Plant, Pocha, Pocha, Richards, Robinson, Rodriguez-Boulan, Rodriguez-Fraticelli, Rodriguez-Fraticelli, Roeth, Roland, Rossi, Sahlender, Sakamori, Sato, Satoh, Schluter, Schottenfeld-Roames, Shafaq-Zadah, Sherrard, Shewan, Shivas, Sobajima, Sollier, Stepensky, Suzuki, Takahama, Taniguchi, Tepass, Tepass, Tepass, Thuenauer, Toro, Vaccari, Vaccari, Varelas, Vermeer, Vogel, Vogel, Vreede, Wang, Wang, Wang, Wedlich-Soldner, Wei, Wiegerinck, Willenborg, Winter, Xiong, Xiong, Yamanaka, Yamanaka, Zhang, Zhang, Zhou, Zihni, Zou   +157 more
core   +1 more source