Results 11 to 20 of about 282,105 (396)
Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. [PDF]
bioRxiv, 2019 Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to ...
Ahn, In Sook +15 more
core +3 more sources
Nature Communications, 2022 Aberrant amino acid metabolism is a common event in obesity. Particularly, subjects with obesity are characterized by the excessive plasma kynurenine (Kyn).
Teng Huang +16 more
semanticscholar +1 more source
Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance
Journal of experimental & clinical cancer research : CR, 2022 Therapeutic resistance occurs in most patients with multiple myeloma (MM). One of the key mechanisms for MM drug resistance comes from the interaction between MM cells and adipocytes that inhibits drug-induced apoptosis in MM cells; MM cells reprogram ...
Zhiming Wang +7 more
semanticscholar +1 more source
Frontiers in Immunology, 2023 IntroductionLipedema is a painful subcutaneous adipose tissue (SAT) disease characterized by adipocyte hypertrophy, immune cell recruitment, and fibrosis in the affected areas.
Philipp Kruppa +14 more
doaj +1 more source
The Role of Adipocytes and Adipocyte‐Like Cells in the Severity of COVID‐19 Infections
Obesity, 2020 Coronavirus disease‐2019 (COVID‐19), caused by the highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), demonstrates high morbidity and mortality caused by development of a severe acute respiratory syndrome connected with ...
I. Kruglikov, P. Scherer
semanticscholar +1 more source
Role of adipocyte angiotensinogen or angiotensin type 1a receptors in the development of diet-induced atherosclerosis or angiotensin II-induced abdominal aortic aneurysms. [PDF]
JVS Vasc SciAlSiraj Y +5 more
europepmc +3 more sources
STAT5-Interacting Proteins: A Synopsis of Proteins that Regulate STAT5 Activity
Biology, 2017 Signal Transducers and Activators of Transcription (STATs) are key components of the JAK/STAT pathway. Of the seven STATs, STAT5A and STAT5B are of particular interest for their critical roles in cellular differentiation, adipogenesis, oncogenesis, and ...
Ashley A. Able +2 more
doaj +1 more source
Current Biology, 2014 SummaryIn the United States alone, one-third of adults and nearly one-quarter of children are clinically obese. This growing epidemic is of serious concern as obesity confers a significant risk to developing numerous chronic conditions, including cancer, diabetes, and heart disease. The alarming incidence of obesity and the rising costs of treating the
openaire +2 more sources
Nature Communications, 2023 Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understood.
Sang Mun Han +15 more
doaj +1 more source
Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]
, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana +2 more
core +4 more sources