Results 81 to 90 of about 946,668 (293)

Involvement of Cyclooxygenase-2 in Synergistic Effect of Cyclic Stretching and Eicosapentaenoic Acid on Adipocyte Differentiation

Journal of Pharmacological Sciences, 2008
The present study examined the combined effects of fish-oil-derived ω-3 polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and cyclic stretching on the adipocyte differentiation of 3T3-L1 cells.
Yoshiyuki Tanabe, Yumi Matsunaga, Maki Saito, Koichi Nakayama   +3 more
doaj   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Extracellular calcium modulates brown adipocyte differentiation and identity

Scientific Reports, 2017
Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs, Martin Jastroch, Siegfried Ussar   +2 more
doaj   +1 more source

Role of Bmal1 in brown adipocyte differentiation.

, 2013
A. Time course expression of Bmal1 and Clock during brown adipocyte differentiation. B. Oil Red-O staining of adipocytes following 7 days of differentiation. C. qPCR analyses of brown adipocyte gene expression during differentiation. D.
Qi Yu (279662), Siming Li (450229), Jiandie D. Lin (300553), Guo-Xiao Wang (450230)   +3 more
core   +1 more source

Sclerostin Enhances Adipocyte Differentiation in 3T3-L1 Cells [PDF]

, 2016
Sclerostin, a secreted protein encoded by the Sost gene, is produced by osteocytes and is inhibited by osteoblast differentiation and bone formation. Recently, a functional association between bone and fat tissue has been suggested, and a correlation ...
Taihiko Yamaguchi, Tamura, Masato, Mayumi Ukita, Noboru Ohata, Masato Tamura, Ukita, Mayumi, Yamaguchi, Taihiko, Ohata, Noboru   +7 more
core   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Royal Jelly Enhances the Ability of Myoblast C2C12 Cells to Differentiate into Multilineage Cells

Molecules
Royal jelly (RJ) is recognized as beneficial to mammalian health. Multilineage differentiation potential is an important property of mesenchymal stem cells (MSCs). C2C12 cells have an innate ability to differentiate into myogenic cells.
Takumi Ito, Thira Rojasawasthien, Sachiko Yamashita Takeuchi, Hideto Okamoto, Nobuaki Okumura, Tomohiko Shirakawa, Takuma Matsubara, Tatsuo Kawamoto, Shoichiro Kokabu   +8 more
doaj   +1 more source

Complex toxicity as disruption of adipocyte or osteoblast differentiation in human mesenchymal stem cells under the mixed condition of TBBPA and TCDD

Toxicology Reports, 2018
People are frequently and unintentionally exposed to many chemical compounds, such as environmental pollutants and endocrine-disrupting chemicals (EDCs), in food and from the atmosphere.
Hideki Kakutani, Tomohiro Yuzuriha, Ema Akiyama, Teruyuki Nakao, Souichi Ohta   +4 more
doaj   +1 more source

Methyltransferase ans demethylase profiling studies during brown adipocyte differentiation

, 2016
Although brown adipose tissue is important with regard to energy balance, the molecular mechanism of brown adipocyte differentiation has not been extensively studied.
Kyoung Jin Oh, Baek Soo Han, Won Kon Kim, Anna Park, Sang Chul Lee, Min Jeong Son, Kwang-Hee Bae, Da Som Lee   +7 more
core   +1 more source

Layer‐Specific Dermal and Subcutaneous Delivery via Modular LNP–Hydrogel‐Integrated Threaded Microneedles

Advanced Science, EarlyView.
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie, Yixiang Zhang, Shifeng Ling, Yuxuan Huang, Yingying Wei, Rao Fu, Jiahao He, Baikun Liu, Lucia Zhou, Kaifeng Huo, Yida Wang, Qingfeng Li, Yawei Du, Wenguo Cui, Yun Xie   +14 more
wiley   +1 more source