The role of extracellular vesicles in the context of (inter-)cellular communication contributing to adipose tissue dysfunction in lipedema. [PDF]
Morawitz KH, Gross JC.
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A mitochondrial-stress adipocyte-macrophage circuit sustaining metaflammation in human type 2 diabetic adipose tissue. [PDF]
Ji H +10 more
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Pck1 Deficiency Drives Mitochondrial Dysfunction and Cellular Senescence in Adipocytes. [PDF]
Lei Y +12 more
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Diet-Induced Browning of White Adipose Tissue: Molecular Targets, Mechanisms, and Therapeutic Potential. [PDF]
Yang ZD +5 more
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Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro
Journal of Cellular Physiology, 2017White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are incompletely explored in their details.
Maurizi G +17 more
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The biology of white adipocyte proliferation
Obesity Reviews, 2001SummaryExpanded adipose tissue mass increases the risk for many clinical conditions including diabetes, hypertension, coronary atherosclerotic heart disease, and some forms of cancer. Therefore, it is imperative that we understand the mechanisms by which fat pads expand. The enlargement of fat cells during the development of obesity has been previously
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An Approach to Monitor Exocytosis in White Adipocytes
2020Exocytosis, the fusion of vesicles with the plasma membrane, can be measured with the patch-clamp technique as increases in membrane capacitance. Here we provide detailed information on how to monitor white adipocyte exocytosis using this method. We describe how to isolate the stromal vascular fraction of cells (SVF) within adipose tissue and how to ...
Ali M, Komai +3 more
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Metabolism of lipids in human white adipocyte
Diabetes & Metabolism, 2004Adipose tissue is considered as the body's largest storage organ for energy in the form of triacylglycerols, which are mobilized through lipolysis process, to provide fuel to other organs and to deliver substrates to liver for gluconeogenesis (glycerol) and lipoprotein synthesis (free fatty acids).
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Leptin biosynthetic pathway in white adipocytes
Biochemistry and Cell Biology, 2006The aim of this study was to determine through morphological and biochemical means the biosynthetic and secretory pathway followed by leptin in adipocytes. Immunocytochemistry revealed the presence of leptin in the rough endoplasmic reticulum, the Golgi apparatus, and in numerous small vesicles along the plasma membrane of white adipo cytes. In vitro,
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The histaminase activity of rat white adipocytes
Inflammation Research, 1997Investigate the reaction conditions which allow the measurement of high affinity histamine oxidation.Isolated rat white adipocytes.The histaminase activity of rat white adipocytes and its inhibition by B24 and MDL 72274 was measured fluorimetrically or radiochemically in different experimental conditions.Histamine oxidation by rat white adipocytes is ...
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