Results 211 to 220 of about 62,660 (267)

Osteocytes orchestrate browning: emerging signals in bone-fat crosstalk: a systematic review. [PDF]

Front Endocrinol (Lausanne)
Anees H, Jahed V, Sabouri Z, Jamous R, Pennisi CP, Heiss C, El Khassawna T.   +6 more
europepmc   +1 more source

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source

Modelling adipose tissue-cancer crosstalk: a three-dimensional perspective. [PDF]

Oncogene
Strusi G, Suelzu CM, Stebbing J.
europepmc   +1 more source

The Postprandial Chronobiome in Interorgan Glucose Homeostasis

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
The postprandial chronobiome framework proposes that meal‐timed oscillations in microbial communities and metabolites may interact with host tissue clocks to shape glucose handling. The liver is the best‐supported temporal interpreter, while phase‐aware human studies are needed to establish causal interorgan effects.
Josko Bozic, Roko Santic, Marko Kumric
wiley   +1 more source

Remodeling the marrow fat niche: BMAT in cancer bone metastases and hematological malignancies. [PDF]

Curr Opin Endocr Metab Res
Podgorski I.
europepmc   +1 more source

Chemokine receptor CCR1 restrains adipose tissue remodelling via cAMP/PKA/CREB signalling and adipocyte‒macrophage crosstalk in mice

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
CCR1 expression is significantly elevated in adipose tissue of obese individuals. Systemic and adipocyte‐specific Ccr1 deletion promotes fat browning via cAMP/PKA/CREB activation and M2 macrophage polarisation, protecting against obesity. Pharmacological blockade of CCR1 suppresses obesity progression, highlighting its potential as a novel target for ...
Suili Cai, Mengchen Ma, Yuqin Zhu, Mengru Shi, Xiaoyan Dai, Yujie Wang, Mengru Li, Yanwen Yu, Yajiao Wang, Liang Xu   +9 more
wiley   +1 more source

S-nitrosoglutathione reductase GSNOR drives age-related obesity by promoting adipose tissue whitening through de-nitrosation of Beclin-1. [PDF]

Nat Commun
Qiao X, Xie T, Zhang Y, Sun C, Wu X, Chen Y, Yao Q, Shi H, Li S, Zhao H, Wang T, Meng J, Zhou L, Niu M, Hu Y, Liu H, Chen C.   +16 more
europepmc   +1 more source

Effects of Exogenous Monosodium Glutamate on GABA Accumulation and Volatile/Nonvolatile Metabolites in Black Highland Barley

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
wiley   +1 more source

Time-restricted feeding improves metabolic flexibility, promotes beiging, and mitigates fibro-inflammation in the adipose tissue of aged mice. [PDF]

J Gerontol A Biol Sci Med Sci
Natarajan D, Milan M, Reyff Z, Negri S, Ekambaram S, Varshney RR, Rudolph MC, Tarantini S, Balasubramanian P.   +8 more
europepmc   +1 more source

Past, present, and future of thermogenic fat research: A bibliometric analysis from 2000 to 2023. [PDF]

Medicine (Baltimore)
Xie H, Chen L, Long B, Song X, Jiang M, Song Z.   +5 more
europepmc   +1 more source