Results 101 to 110 of about 160,546 (318)
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu+13 more
wiley +1 more source
Combinations of Tibetan tea and medicine food homology herbs: A new strategy for obesity prevention
Combinations of Tibetan Tea and Medicine Food Homology Herbs, A new Strategy for Obesity Prevention. Abstract Obesity has become a significant global public health problem. Functional drinks have been an essential direction for obesity prevention research.
Ye Yuan+7 more
wiley +1 more source
Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie+10 more
wiley +1 more source
Edible red seaweed G. furcata alleviates obesity and associated metabolic disorders in mice fed a high fat diet by suppressing intestinal lipid absorption, oxidative stress and inflammation. Abstract Obesity and diabetes are serious, chronic medical conditions associated with a wide range of life‐threatening conditions.
Shigeru Murakami+9 more
wiley +1 more source
AdipoCount: A New Software for Automatic Adipocyte Counting
Obesity has spread worldwide and become a common health problem in modern society. One typical feature of obesity is the excessive accumulation of fat in adipocytes, which occurs through the following two physiological phenomena: hyperplasia (increase in
Xuhao Zhi+7 more
doaj +1 more source
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang+10 more
wiley +1 more source
Regional specialization and fate specification of bone stromal cells in skeletal development
Summary: Bone stroma contributes to the regulation of osteogenesis and hematopoiesis but also to fracture healing and disease processes. Mesenchymal stromal cells from bone (BMSCs) represent a heterogenous mixture of different subpopulations with ...
Kishor K. Sivaraj+6 more
doaj
Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation
Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Manami Igata+27 more
doaj +1 more source
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu+21 more
wiley +1 more source
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo+14 more
wiley +1 more source