Results 91 to 100 of about 265,737 (264)

Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells. [PDF]

, 2014
The increased incidence of obesity and metabolic disease underscores the importance of elucidating the biology of adipose tissue development. The recent discovery of cell surface markers for prospective identification of adipose precursor cells (APCs) in
Costa, Maria José, Du, Hongqing, Feldman, Brian J, Krueger, Katherine C   +3 more
core   +2 more sources

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells

Journal of Lipid Research, 2003
Exposure of preadipocytes to long-chain fatty acids induces the expression of several markers of adipocyte differentiation. In an attempt to identify novel genes and proteins that are regulated by fatty acids in preadipocytes, we performed a substractive
Anissa Abderrahim-Ferkoune, Olivier Bezy, Chiara Chiellini, Margherita Maffei, Paul Grimaldi, Frédéric Bonino, Naïma Moustaid-Moussa, Fabio Pasqualini, Alberto Mantovani, Gérard Ailhaud, Ez-Zoubir Amri   +10 more
doaj   +1 more source

The relationship between insulin binding, insulin activation of insulin-receptor tyrosine kinase, and insulin stimulation of glucose uptake in isolated rat adipocytes [PDF]

, 1991
We have studied the relationship between insulin activation of insulin-receptor kinase and insulin stimulation of glucose uptake in isolated rat adipocytes.
Drenkhan, M., Klein, H. H., Matthaei, S., Ries, W., Scriba, Peter Christian   +4 more
core  

COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]

, 1993
Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ, Mathieson, PW, Oliveria, DB, Peters, DK, Würzner, R   +4 more
core   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Dermal white adipose tissue: a new component of the thermogenic response

Journal of Lipid Research, 2015
Recent literature suggests that the layer of adipocytes embedded in the skin below the dermis is far from being an inert spacer material. Instead, this layer of dermal white adipose tissue (dWAT) is a regulated lipid layer that comprises a crucial ...
Caroline M. Alexander, Ildiko Kasza, C-L. Eric Yen, Scott B. Reeder, Diego Hernando, Richard L. Gallo, Colin A.B. Jahoda, Valerie Horsley, Ormond A. MacDougald   +8 more
doaj   +1 more source

GALNT2 as a novel modulator of adipogenesis and adipocyte insulin signaling [PDF]

, 2019
Background/objectives: A better understanding of adipose tissue biology is crucial to tackle insulin resistance and eventually coronary heart disease and diabetes, leading causes of morbidity and mortality worldwide.
Antonucci, A., De Bonis, Maria Caterina, Di Paola, R., Mangiacotti, D., Marucci, A., Scarale, M. G., Trischitta, V.   +6 more
core   +1 more source

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Journal of Lipid Research, 2018
Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose tissue was more ...
Andrew E. Libby, Elise S. Bales, Jenifer Monks, David J. Orlicky, James L. McManaman   +4 more
doaj   +1 more source