The role of endoplasmic reticulum in human adipose tissue [PDF]
Adipose tissue plays a central role in the regulation of metabolic homeostasis. In obesity adipocytes are challenged by many insults: surplus energy, inflammation, insulin resistance and considerable endoplasmic reticulum (ER) stress.
Alhusaini, S. (Saif)
core
ACAT1/SOAT1 maintains adipogenic ability in preadipocytes by regulating cholesterol homeostasis
Journal of Lipid ResearchMaintaining cholesterol homeostasis is critical for preserving adipocyte function during the progression of obesity. Despite this, the regulatory role of cholesterol esterification in governing adipocyte expandability has been understudied. Acyl-coenzyme
Qing Liu +9 more
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Plasticity of Thermogenic Adipocytes
, 2018 Adipocytes are mesenchymal cells specialized in storing large quantities of lipids in the cytosol as lipid droplets. They are found in adipose tissues such as those found subcutaneously or intraabdominally, as well as in many smaller depots within or ...
Andersen, Maja Worm +2 more
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Insulin receptor trafficking steers insulin action
Molecular Metabolism, 2016 Simone Hausmann, Siegfried Ussar
doaj +1 more source
The HLA-B associated transcript 1 (BAT1) expression in human adipose tissue : BAT1 modulation with increasing adiposity and diabetes [PDF]
Obesity and type 2 diabetes (T2DM) are both inflammatory disorders with parallel escalating epidemics. Novel insights provided by the new biology suggest common pathways by which several pathogenic components of obesity affect glucose metabolism and ...
Lois, Konstantinos
core
, 2014 Panel A, (a), Cells were exposed to antalarmin (a CRF1 receptor antagonist) and/or astressin-2B (a CRF2 receptor antagonist) and the decrease of specific binding activity was measured.
John Melissas (565532) +6 more
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Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop [PDF]
, 2016 Obesity has long been linked with prostate cancer progression, although the underlying mechanism is still largely unknown. Here, we report that adipocytes promote the enrichment of prostate cancer stem cells (CSCs) through a vicious cycle of autocrine ...
Liu, Ji +11 more
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Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus [PDF]
There is a worldwide epidemic of obesity. Weight rise is a consequence of continuous positive energy balance which leads to accumulation of body fat. Recent insights into adipose tissue (AT) biology have led to the conclusion that the adipocyte is not
Kos, Katarina
core
Browning of human white adipocytes
, 2012 Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request.
Zhang, Yan
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Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
, 1994 Korndörfer, Andrea +3 more
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