Results 41 to 50 of about 352,221 (407)
Circulation, 2020 Supplemental Digital Content is available in the text. Background: Diabetes mellitus exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury.
Lu Gan +10 more
semanticscholar +1 more source
Frontiers in Oncology, 2021 BackgroundIt is well known that obesity is one of the risks for incurrence and development in breast cancer patients. Long non-coding RNAs (lncRNAs) are reported to participate in the composition of tumor microenvironment and to regulate breast cancer ...
Xin-Hui Cao +9 more
doaj +1 more source
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
core +2 more sources
European Journal of Cell Biology, 2013 Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq Ali +4 more
openaire +3 more sources
Milestones in Molecular Mechanisms of Adipogenesis and Adipose Tissue Plasticity [PDF]
International Journal of Biomedicine, 2021 This review focuses on the problem of adipogenesis mechanisms and the biological role of adipose tissue (AT) in the human body. Over the past decades, various types of adipocytes have been identified and characterized—white, brown, beige, yellow, and ...
Olga P. Shatova +4 more
doaj +1 more source
Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
, 1994 . Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard +3 more
core +3 more sources
Cancer-associated adipocytes: emerging supporters in breast cancer
Journal of experimental & clinical cancer research : CR, 2020 Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis and recurrence rate, and adipocytes are the largest components in breast tissue.
Chongru Zhao +8 more
semanticscholar +1 more source
Weighing in on Adipocyte Precursors [PDF]
Cell Metabolism, 2014 Obesity, defined as an excessive increase in white adipose tissue (WAT), is a global health epidemic. In obesity, WAT expands by increased adipocyte size (hypertrophy) and number (hyperplasia). The location and cellular mechanisms of WAT expansion greatly affect the pathogenesis of obesity.
Ryan Berry +2 more
openaire +3 more sources
BMC Cancer, 2020 Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré +10 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Differentiating 3T3-L1 pre-adipocytes are a mixture of non-identical culture cells. It is vital to identify the cell types that respond to the induction stimulus to understand the pre-adipocyte potential and the mature adipocyte behavior.
Mahmoud Ahmed +2 more
doaj +1 more source