Results 31 to 40 of about 237,921 (307)

Effect of metformin on transcriptome and adipokinome of adipocytes of local fat deposts of patients with ischemic heart disease

Ожирение и метаболизм, 2023
BACKGROUND: The information available to date on the effect of metformin on the transcriptome and secretory capacity of adipocytes in human adipose tissue (AT) is scarce and contradictory.
Yu. A. Dyleva, O. V. Gruzdeva, E. V. Belik, D. A. Borodkina, M. Yu. Sinitskiy, S. V. Ivanov, O. L. Barbarash   +6 more
doaj   +1 more source

Overexpression of DGAT2 Regulates the Differentiation of Bovine Preadipocytes

Animals, 2023
Triacylglycerols (TAGs) are a major component of intramuscular fat. Diacylglycerol O-acyltransferase 2(DGAT2) expression determines the rate of TAG synthesis.
Pan-Pan Guo, Xin Jin, Jun-Fang Zhang, Qiang Li, Chang-Guo Yan, Xiang-Zi Li   +5 more
doaj   +1 more source

Cancer-associated adipocytes: emerging supporters in breast cancer

Journal of experimental & clinical cancer research : CR, 2020
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis and recurrence rate, and adipocytes are the largest components in breast tissue.
Chongru Zhao, Min Wu, N. Zeng, Mingchen Xiong, Weijie Hu, Wenchang Lv, Yi Yi, Qi Zhang, Yiping Wu   +8 more
semanticscholar   +1 more source

Ramon Flour (Brosimum alicastrum Swartz) Ameliorates Hepatic Lipid Accumulation, Induction of AMPK Phosphorylation, and Expression of the Hepatic Antioxidant System in a High-Fat-Diet-Induced Obesity Mouse Model

Antioxidants, 2023
Excessive consumption of fat and carbohydrates, together with a decrease in traditional food intake, has been related to obesity and the development of metabolic alterations.
Trinidad Eugenia Cu-Cañetas, Laura A. Velázquez-Villegas, Mariana Manzanilla-Franco, Teresa del Rosario Ayora-Talavera, Juan José Acevedo-Fernández, Enrique Barbosa-Martín, Claudia C. Márquez-Mota, Adriana M. López-Barradas, Lilia G. Noriega, Martha Guevara-Cruz, Ana Ligia Gutiérrez-Solís, Azalia Avila-Nava   +11 more
doaj   +1 more source

Small Extracellular Microvesicles Mediated Pathological Communications between Dysfunctional Adipocytes and Cardiomyocytes as a Novel Mechanisms Exacerbating Ischemia/Reperfusion Injury in Diabetic Mice

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Diabetes mellitus exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury.
Lu Gan, Dina Xie, Jing Liu, Wayne Bond Lau, T. Christopher, B. Lopez, Ling Zhang, E. Gao, W. Koch, Xinliang Ma, Yajing Wang   +10 more
semanticscholar   +1 more source

Production of Reactive Oxygen Species by Epicardial Adipocytes Is Associated with an Increase in Postprandial Glycemia, Postprandial Insulin, and a Decrease in Serum Adiponectin in Patients with Severe Coronary Atherosclerosis

Biomedicines, 2022
Purpose. This work investigates the relations between the production of reactive oxygen species (ROS) by epicardial adipose tissue (EAT) adipocytes and parameters of glucose/insulin metabolism, circulating adipokines levels, and severity of coronary ...
Natalia V. Naryzhnaya, Olga A. Koshelskaya, Irina V. Kologrivova, Tatiana E. Suslova, Olga A. Kharitonova, Sergey L. Andreev, Alexander S. Gorbunov, Boris K. Kurbatov, Alla A. Boshchenko   +8 more
doaj   +1 more source

Regulatory mechanism of white adipocyte browning and research advances [PDF]

BIO Web of Conferences
Adipose tissue has energy storage and metabolic functions, and its content is highly correlated with an individual’s obesity status. The relative proportions of white adipocytes, brown adipocytes, and beige adipocytes are also important in regulating ...
Wang Zihan
doaj   +1 more source

Adipocyte and adipogenesis

European Journal of Cell Biology, 2013
Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq, Ali, Warren E, Hochfeld, Renier, Myburgh, Michael S, Pepper   +3 more
openaire   +2 more sources

Cancer-associated adipocytes: key players in breast cancer progression

Journal of Hematology & Oncology, 2019
Adipocytes are one of the primary stromal cells in many tissues, and they are considered to play an active role in the tumor microenvironment. Cancer-associated adipocytes (CAAs) are not only found adjacent to cancer cells, but also communicate with ...
Qi Wu, Bei Li, Zhiyu Li, Juanjuan Li, Si Sun, Shengrong Sun   +5 more
semanticscholar   +1 more source

Adipocytes Directly Affect Coronary Artery Disease Pathogenesis via Induction of Adipokine and Cytokine Imbalances

Frontiers in Immunology, 2019
This study aimed to investigate the adipokine and cytokine profiles of adipocytes from epicardial and subcutaneous adipose tissues in interconnection with the visceral adipose tissue area and the biochemical and clinical characteristics of patients with ...
Olga Gruzdeva, Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Daria Borodkina, Olga Akbasheva, Larisa Antonova, Vera Matveeva, Ekaterina Belik, Sergei Ivanov, Anton Sotnikov, Kirill Kozyrin, Natalia Brel, Maxim Sinitsky, Victoria Karetnikova, Victoria Karetnikova, Alexander Kokov, Evgenya Bychkova, Tamara Pecherina, Olga Barbarash, Olga Barbarash   +20 more
doaj   +1 more source