AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]
PLoS ONE, 2016 Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman +18 more
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In vitro and ex vivo models of adipocytes.
American Journal of Physiology - Cell Physiology, 2021 Adipocytes are specialized cells with pleiotropic roles in physiology and pathology. Several types of fat cells with distinct metabolic properties co-exist in various anatomically defined fat depots in mammals. White, beige and brown adipocytes differ in
J. Dufau +11 more
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The role of adipocytes and adipocyte-like cells in the severity of COVID-19 infections
Obesity, 2020 Coronavirus disease‐2019 (COVID‐19), caused by the highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), demonstrates high morbidity and mortality caused by development of a severe acute respiratory syndrome connected with ...
I. Kruglikov, P. Scherer
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A Rare Clinical Case of Lipoma in the Soft Tissues of the Sublingual Space: A Case Report [PDF]
Journal of Biomedical & Clinical Research, 2021 This report presents clinical case with a histopathologically established lipoma of the sublingual space. Lipomas are benign mesenchymal neoplasms produced by adipocytes.
Petya Kanazirska +2 more
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Beige Adipocytes are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
Cell, 2012 Summary Brown fat defends against hypothermia and obesity through thermogenesis mediated by mitochondrial UCP1. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1 ...
Jun Wu +16 more
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Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]
, 1994 The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Wetekam, Eva-Marlen +5 more
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Current Biology, 2014 SummaryIn the United States alone, one-third of adults and nearly one-quarter of children are clinically obese. This growing epidemic is of serious concern as obesity confers a significant risk to developing numerous chronic conditions, including cancer, diabetes, and heart disease. The alarming incidence of obesity and the rising costs of treating the
openaire +2 more sources
Frontiers in Oncology, 2023 The unique properties of the bone marrow (BM) allow for migration and proliferation of multiple myeloma (MM) cells while also providing the perfect environment for development of quiescent, drug-resistant MM cell clones.
Heather Fairfield +17 more
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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*)
Journal of Biological Chemistry, 1995 We describe a novel 30-kDa secretory protein, Acrp30 (adipocyte complement-related protein of 30 kDa), that is made exclusively in adipocytes and whose mRNA is induced over 100-fold during adipocyte differentiation.
P. Scherer +4 more
semanticscholar +1 more source
The role of melanocortins and cytokines in human adipose tissue and adipocytes [PDF]
, 2007 During the last decades obesity has become a major health problem in developed countries, and more recently also in the developing countries it is seriously affecting parts of the populations.
Hoch, Matthias
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