Results 21 to 30 of about 237,921 (307)

The role of adipocytes and adipocyte-like cells in the severity of COVID-19 infections

Obesity, 2020
Coronavirus disease‐2019 (COVID‐19), caused by the highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), demonstrates high morbidity and mortality caused by development of a severe acute respiratory syndrome connected with ...
I. Kruglikov, P. Scherer
semanticscholar   +1 more source

A Rare Clinical Case of Lipoma in the Soft Tissues of the Sublingual Space: A Case Report [PDF]

Journal of Biomedical & Clinical Research, 2021
This report presents clinical case with a histopathologically established lipoma of the sublingual space. Lipomas are benign mesenchymal neoplasms produced by adipocytes.
Petya Kanazirska, Mery Hristamyan-Cilev, Nikolay Kanazirski   +2 more
doaj   +3 more sources

Beige Adipocytes are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Cell, 2012
Summary Brown fat defends against hypothermia and obesity through thermogenesis mediated by mitochondrial UCP1. Recent data suggest that there are two distinct types of brown fat: classical brown fat derived from a myf-5 cellular lineage and UCP1 ...
Jun Wu, P. Boström, L. Sparks, L. Ye, J. Choi, An-Hoa Giang, M. Khandekar, K. Virtanen, P. Nuutila, G. Schaart, Kexin Huang, H. Tu, W. Lichtenbelt, J. Hoeks, S. Enerbäck, P. Schrauwen, B. Spiegelman   +16 more
semanticscholar   +1 more source

Adipocytes [PDF]

Current Biology, 2014
SummaryIn the United States alone, one-third of adults and nearly one-quarter of children are clinically obese. This growing epidemic is of serious concern as obesity confers a significant risk to developing numerous chronic conditions, including cancer, diabetes, and heart disease. The alarming incidence of obesity and the rising costs of treating the
openaire   +2 more sources

Development and characterization of three cell culture systems to investigate the relationship between primary bone marrow adipocytes and myeloma cells

Frontiers in Oncology, 2023
The unique properties of the bone marrow (BM) allow for migration and proliferation of multiple myeloma (MM) cells while also providing the perfect environment for development of quiescent, drug-resistant MM cell clones.
Heather Fairfield, Heather Fairfield, Heather Fairfield, Rebecca Condruti, Mariah Farrell, Mariah Farrell, Mariah Farrell, Reagan Di Iorio, Reagan Di Iorio, Carlos A. Gartner, Carlos A. Gartner, Carlos A. Gartner, Calvin Vary, Calvin Vary, Calvin Vary, Michaela R. Reagan, Michaela R. Reagan, Michaela R. Reagan   +17 more
doaj   +1 more source

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*)

Journal of Biological Chemistry, 1995
We describe a novel 30-kDa secretory protein, Acrp30 (adipocyte complement-related protein of 30 kDa), that is made exclusively in adipocytes and whose mRNA is induced over 100-fold during adipocyte differentiation.
P. Scherer, Suzanne E. Williams, M. Fogliano, G. Baldini, H. Lodish   +4 more
semanticscholar   +1 more source

Senolytic effects of quercetin in an in vitro model of pre-adipocytes and adipocytes induced senescence

Scientific Reports, 2021
The dysfunction of adipose tissue with aging and the accumulation of senescent cells has been implicated in the pathophysiology of chronic diseases.
E. Zoico, Nicole Nori, E. Darra, M. Tebon, V. Rizzatti, Gabriella Policastro, Annamaria De Caro, A. Rossi, F. Fantin, M. Zamboni   +9 more
semanticscholar   +1 more source

Extracellular calcium modulates brown adipocyte differentiation and identity

Scientific Reports, 2017
Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs, Martin Jastroch, Siegfried Ussar   +2 more
doaj   +1 more source

Transferrin Receptor Functionally Marks Thermogenic Adipocytes

Frontiers in Cell and Developmental Biology, 2020
BackgroundThermogenic adipocytes, including beige and brown adipocytes, are critical for thermogenesis and energy homeostasis. Identification of functional cell surface markers of thermogenic adipocytes is of significance for potential application in ...
Jin Qiu, Zhiyin Zhang, Sainan Wang, Yanru Chen, Caizhi Liu, Sainan Xu, Dongmei Wang, Junlei Su, Mengshan Ni, Jian Yu, Xiangdi Cui, Lu Ma, Tianhui Hu, Yepeng Hu, Xuejiang Gu, Xinran Ma, Xinran Ma, Jiqiu Wang, Lingyan Xu   +18 more
doaj   +1 more source

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

BMC Cancer, 2020
Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux   +10 more
doaj   +1 more source