Results 41 to 50 of about 237,921 (307)
A lipase-independent pathway of lipid release and immune modulation by adipocytes
Science, 2019 Exosomes that fatten immune cells Adipose tissue in mammals contains not only adipocytes (fat cells) but also a variety of immune cells—most notably, macrophages.
Stephen E. Flaherty +5 more
semanticscholar +1 more source
The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis
Journal of Lipid Research, 2005 This study assessed the effects of selective inhibitors of 3′,5′-cyclic nucleotide phosphodiesterases (PDEs) on adipocyte lipolysis. IC224, a selective inhibitor of type 1 phosphodiesterase (PDE1), suppressed lipolysis in murine 3T3-L1 adipocytes (69.6 ±
Peter B. Snyder +4 more
doaj +1 more source
Stromal-vascular fraction of adipose tissue as an alternative source of cellular material for regenerative medicine [PDF]
The Ukrainian Biochemical Journal, 2021 Adipose tissue is the most convenient source of cellular material for regenerative medicine as it can be obtained in significant quantities via cosmetic liposuction, lipoaspiration of subcutaneous fat or by excision of fat deposits.
A. S. Sultanova +2 more
doaj +1 more source
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Cell Death and Differentiation, 2016 Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered in bone marrow, are multipotent cells capable of differentiating into mature cells of several mesenchymal tissues, such as fat and bone.
Q. Chen +15 more
semanticscholar +1 more source
Epigenetic Regulation of Neuregulin-1 Tunes White Adipose Stem Cell Differentiation
Cells, 2020 Expansion of subcutaneous adipose tissue by differentiation of new adipocytes has been linked to improvements in metabolic health. However, an expandability limit has been observed wherein new adipocytes cannot be produced, the existing adipocytes become
Alyssa D. Cordero +5 more
doaj +1 more source
Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche
Frontiers in Oncology, 2022 Acute myeloid leukaemia (AML) is a highly proliferative cancer characterised by infiltration of immature haematopoietic cells in the bone marrow (BM). AML predominantly affects older people and outcomes, particularly in this difficult to treat population
Rebecca S. Maynard +5 more
doaj +1 more source
Compression-induced dedifferentiation of adipocytes promotes tumor progression
Science Advances, 2020 Physical compression–induced dedifferentiation of adipocytes promotes tumor progression. Dysregulated physical stresses are generated during tumorigenesis that affect the surrounding compliant tissues including adipocytes. However, the effect of physical
Yiwei Li +9 more
semanticscholar +1 more source
Nanomaterials, 2021 In this research, a simple, green approach was employed to synthesize silver nanoparticles with the aid of Ziziphus spina-christi (L.) methanol root extract, which can act as a reducing, capping agent to treat obesity and inflammation. Globally, Ziziphus
Abu ElGasim Ahmed Yagoub +5 more
doaj +1 more source
Adipocyte, 2012 When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
openaire +2 more sources
Bone marrow adipocytes promote the regeneration of stem cells and hematopoiesis by secreting SCF
Nature Cell Biology, 2017 Endothelial cells and leptin receptor+ (LepR+) stromal cells are critical sources of haematopoietic stem cell (HSC) niche factors, including stem cell factor (SCF), in bone marrow.
B. Zhou +6 more
semanticscholar +1 more source