Results 51 to 60 of about 267,086 (349)

Cancer-associated adipocytes: emerging supporters in breast cancer

Journal of experimental & clinical cancer research : CR, 2020
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis and recurrence rate, and adipocytes are the largest components in breast tissue.
Chongru Zhao, Min Wu, N. Zeng, Mingchen Xiong, Weijie Hu, Wenchang Lv, Yi Yi, Qi Zhang, Yiping Wu   +8 more
semanticscholar   +1 more source

Adipocyte and adipogenesis

European Journal of Cell Biology, 2013
Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq, Ali, Warren E, Hochfeld, Renier, Myburgh, Michael S, Pepper   +3 more
openaire   +2 more sources

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

BMC Cancer, 2020
Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux   +10 more
doaj   +1 more source

Ramon Flour (Brosimum alicastrum Swartz) Ameliorates Hepatic Lipid Accumulation, Induction of AMPK Phosphorylation, and Expression of the Hepatic Antioxidant System in a High-Fat-Diet-Induced Obesity Mouse Model

Antioxidants, 2023
Excessive consumption of fat and carbohydrates, together with a decrease in traditional food intake, has been related to obesity and the development of metabolic alterations.
Trinidad Eugenia Cu-Cañetas, Laura A. Velázquez-Villegas, Mariana Manzanilla-Franco, Teresa del Rosario Ayora-Talavera, Juan José Acevedo-Fernández, Enrique Barbosa-Martín, Claudia C. Márquez-Mota, Adriana M. López-Barradas, Lilia G. Noriega, Martha Guevara-Cruz, Ana Ligia Gutiérrez-Solís, Azalia Avila-Nava   +11 more
doaj   +1 more source

Small Extracellular Microvesicles Mediated Pathological Communications between Dysfunctional Adipocytes and Cardiomyocytes as a Novel Mechanisms Exacerbating Ischemia/Reperfusion Injury in Diabetic Mice

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Diabetes mellitus exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury.
Lu Gan, Dina Xie, Jing Liu, Wayne Bond Lau, T. Christopher, B. Lopez, Ling Zhang, E. Gao, W. Koch, Xinliang Ma, Yajing Wang   +10 more
semanticscholar   +1 more source

Production of Reactive Oxygen Species by Epicardial Adipocytes Is Associated with an Increase in Postprandial Glycemia, Postprandial Insulin, and a Decrease in Serum Adiponectin in Patients with Severe Coronary Atherosclerosis

Biomedicines, 2022
Purpose. This work investigates the relations between the production of reactive oxygen species (ROS) by epicardial adipose tissue (EAT) adipocytes and parameters of glucose/insulin metabolism, circulating adipokines levels, and severity of coronary ...
Natalia V. Naryzhnaya, Olga A. Koshelskaya, Irina V. Kologrivova, Tatiana E. Suslova, Olga A. Kharitonova, Sergey L. Andreev, Alexander S. Gorbunov, Boris K. Kurbatov, Alla A. Boshchenko   +8 more
doaj   +1 more source

Regulatory mechanism of white adipocyte browning and research advances [PDF]

BIO Web of Conferences
Adipose tissue has energy storage and metabolic functions, and its content is highly correlated with an individual’s obesity status. The relative proportions of white adipocytes, brown adipocytes, and beige adipocytes are also important in regulating ...
Wang Zihan
doaj   +1 more source

Cancer-associated adipocytes: key players in breast cancer progression

Journal of Hematology & Oncology, 2019
Adipocytes are one of the primary stromal cells in many tissues, and they are considered to play an active role in the tumor microenvironment. Cancer-associated adipocytes (CAAs) are not only found adjacent to cancer cells, but also communicate with ...
Qi Wu, Bei Li, Zhiyu Li, Juanjuan Li, Si Sun, Shengrong Sun   +5 more
semanticscholar   +1 more source

Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine [PDF]

, 2014
Brown adipocytes help to maintain body temperature by the expression of a unique set of genes that facilitate cellular metabolic events including uncoupling protein 1-dependent thermogenesis.
Christian, Mark, Christian, M
core   +1 more source

A lipase-independent pathway of lipid release and immune modulation by adipocytes

Science, 2019
Exosomes that fatten immune cells Adipose tissue in mammals contains not only adipocytes (fat cells) but also a variety of immune cells—most notably, macrophages.
Stephen E. Flaherty, Ambar Grijalva, Xiaoyuan Xu, E. Ables, Alireza Nomani, A. Ferrante   +5 more
semanticscholar   +1 more source