Results 11 to 20 of about 158,878 (217)

Extracellular calcium modulates brown adipocyte differentiation and identity

open access: yesScientific Reports, 2017
Brown adipocytes are important in regulating non-shivering thermogenesis, whole body glucose and lipid homeostasis. Increasing evidence supports an important role of metabolites as well as macro- and micronutrients in brown adipocyte differentiation and ...
Ines Pramme-Steinwachs   +2 more
doaj   +1 more source

PiT2 deficiency prevents increase of bone marrow adipose tissue during skeletal maturation but not in OVX-induced osteoporosis

open access: yesFrontiers in Endocrinology, 2022
The common cellular origin between bone marrow adipocytes (BMAds) and osteoblasts contributes to the intimate link between bone marrow adipose tissue (BMAT) and skeletal health. An imbalance between the differentiation ability of BMSCs towards one of the
Giulia Frangi   +17 more
doaj   +1 more source

Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche

open access: yesCellular & Molecular Biology Letters, 2023
Background One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state.
Aleksandra Simiczyjew   +6 more
doaj   +1 more source

Roles of estrogens, estrogen-like compounds, and endocrine disruptors in adipocytes

open access: yesFrontiers in Endocrinology, 2022
Women are subject to constitutional changes after menopause, which increases conditions and diseases prone to cardiovascular risks such as obesity and diabetes mellitus.
Fernando Lizcano
doaj   +1 more source

Skin-associated adipocytes in skin barrier immunity: A mini-review

open access: yesFrontiers in Immunology, 2023
The skin contributes critically to health via its role as a barrier tissue against a multitude of external pathogens. The barrier function of the skin largely depends on the uppermost epidermal layer which is reinforced by skin barrier immunity.
Jingyan Guan   +3 more
doaj   +1 more source

Angiogenesis in Adipose Tissue: The Interplay Between Adipose and Endothelial Cells

open access: yesFrontiers in Physiology, 2021
Obesity is a worldwide health problem, and as its prevalence increases, so does the burden of obesity-associated co-morbidities like type 2 diabetes or cardiovascular diseases (CVDs). Adipose tissue (AT) is an endocrine organ embedded in a dense vascular
Jacqueline Herold   +2 more
doaj   +1 more source

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

open access: yesBMC Cancer, 2020
Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion ...
Martin Paré   +10 more
doaj   +1 more source

Anti-Adipogenic Effect of Alchemilla monticola is Mediated Via PI3K/AKT Signaling Inhibition in Human Adipocytes

open access: yesFrontiers in Pharmacology, 2021
Obesity is a persistent and continuously expanding social health concern. Excessive fat mass accumulation is associated with increased risk of chronic diseases including diabetes, atherosclerosis, non-alcoholic steatohepatitis, reproductive dysfunctions ...
Saveta G. Mladenova   +12 more
doaj   +1 more source

UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes

open access: yesFrontiers in Endocrinology, 2020
Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to dissipates energy in the form of heat by uncoupling the mitochondrial proton gradient ...
Kenji Ikeda, Tetsuya Yamada
doaj   +1 more source

Extracellular thiamine concentration influences thermogenic competency of differentiating neck area-derived human adipocytes

open access: yesFrontiers in Nutrition, 2023
IntroductionBrown adipose tissue (BAT) dissipates energy in the form of heat majorly via the mitochondrial uncoupling protein 1 (UCP1). The activation of BAT, which is enriched in the neck area and contains brown and beige adipocytes in humans, was ...
Boglárka Ágnes Vinnai   +9 more
doaj   +1 more source

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