Thermogenic Ability of Uncoupling Protein 1 in Beige Adipocytes in Mice [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +2 more
exaly +2 more sources
Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro [PDF]
Journal of Cellular Physiology, 2017 White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are incompletely explored in their details.
Maurizi G +17 more
core +7 more sources
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
Nature Communications, 2021 Adipose tissue is composed of a variety of cell types, including adipocyte precursor populations, that contribute to adipose tissue function upon differentiation. Here, using scRNA-sequencing of adolescent and adult mouse subcutaneous adipose tissue, the
Lisa Suwandhi +20 more
doaj +1 more source
Regulació nutricional i endocrina de la lipòlisi i la lipoproteïna lipasa en la truita irisada ("Oncorhynchus mykiss") i l'orada ("Sparus aurata") [PDF]
, 2005 [cat] En aquest treball s'ha posat a punt el protocol per a l'obtenció d'adipòcits aïllats de truita irisada (Oncorhynchus mykiss) i d'orada (Sparus aurata).
Albalat Ribé, Amaya
core +6 more sources
Immune Cell Regulation of White Adipose Progenitor Cell Fate
Frontiers in Endocrinology, 2022 Adipose tissue is essential for energy storage and endocrine regulation of metabolism. Imbalance in energy intake and expenditure result in obesity causing adipose tissue dysfunction.
Irem Altun +6 more
doaj +1 more source
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice
BMC Biology, 2023 Background Biological aging is an important factor leading to the development of pathologies associated with metabolic dysregulation, including type 2 diabetes, cancer, cardiovascular and neurodegenerative diseases.
Xue Liu +10 more
doaj +1 more source
PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes
Molecular Metabolism, 2022 Objective: Brown adipocytes play a key role in maintaining body temperature as well as glucose and lipid homeostasis. However, brown adipocytes need to adapt their thermogenic activity and substrate utilization to changes in nutrient availability ...
Jiefu Wang +9 more
doaj +1 more source
Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis
Molecular Metabolism, 2021 Objective: Reorganization of the extracellular matrix is a prerequisite for healthy adipose tissue expansion, whereas fibrosis is a key feature of adipose dysfunction and inflammation.
Francisco Javier Ruiz-Ojeda +15 more
doaj +1 more source
Role of SUMO-Specific Protease 2 in Leptin-Induced Fatty Acid Metabolism in White Adipocytes [PDF]
Diabetes & Metabolism Journal, 2023 Background Leptin is a 16-kDa fat-derived hormone with a primary role in controlling adipose tissue levels. Leptin increases fatty acid oxidation (FAO) acutely through adenosine monophosphate-activated protein kinase (AMPK) and on delay through the SUMO ...
Praise Chanmee Kim +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Abdominal obesity associates with cardiometabolic disease and an accumulation of lipids in the visceral adipose depot, whereas lipid accumulation in the subcutaneous depot is more benign.
Neha Mathur +12 more
doaj +1 more source