Results 1 to 10 of about 106,057 (327)

Dexamethasone-induced selenoprotein S degradation is required for adipogenesis [PDF]

Journal of Lipid Research, 2013
Although adipogenesis is associated with induction of endoplasmic reticulum (ER) stress, the role of selenoprotein S (SEPS1), an ER resident selenoprotein known to regulate ER stress and ER-associated protein degradation, is unknown.
Choon Young Kim, Kee-Hong Kim
doaj   +2 more sources

Weighing in on Adipogenesis [PDF]

Frontiers in Physiology, 2022
Obesity is a growing health concern worldwide because of its contribution to metabolic syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white adipose tissue (WAT) expands through two mechanisms: increase in adipocyte
Elizabeth R. Nunn, Abhijit B. Shinde, Elma Zaganjor   +2 more
doaj   +3 more sources

Pivotal contribution of super-enhancer-driven KLF6 expression to the adipogenesis of human adipose-derived stem cells [PDF]

Inflammation and Regeneration
Background Super-enhancers (SEs), characterized by dense clusters of enhancer elements enriched with transcriptional activator binding sites, are involved in cell differentiation. However, little is known about SE-mediated regulation of adipogenic genes.
Mai-Phuong Nguyen, Kaoru Yamagata, Anh Phuong Nguyen, Tong Zhang, Hidenori Sakai, Uyen Thi Ngo, Yu Shan, Takashi Otsuka, Ngo Thi Dieu Huong, Takafumi Aritomi, Meng Yuan, Shigeaki Kato, Yoshiya Tanaka, Shingo Nakayamada   +13 more
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TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs [PDF]

Stem Cell Research & Therapy
Adipose-derived mesenchymal stem cells (ADSCs) possess the capacity for multidirectional differentiation, including differentiation into adipocytes. However, the molecular mechanisms that control adipogenesis are not yet fully understood.Transcriptional ...
Mei Zhou, Hongyan Zhang, Xiong Miao, Ying Zhao, Long Zhu, Jie Liu, Dongjun Liu   +6 more
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Harnessing adipogenesis to prevent obesity [PDF]

Adipocyte, 2019
Obesity and associated metabolic complications, including diabetes, cardiovascular and hepatic diseases, and certain types of cancers, create a major socioeconomic burden.
Nida Haider, Louise Larose
doaj   +3 more sources

Adipocyte‐specific ablation of plakoglobin in mice does not affect adiposity but results in sexual‐dimorphic effects on weight gain [PDF]

Physiological Reports
The main transcriptional coactivator of the WNT pathway, β‐catenin, is a well‐established regulator of adipogenesis and fat expansion, but our knowledge of how other members of the catenin family participate in adipogenesis remains incomplete.
Frederic Abou Azar, Alexis Vivoli, Arturo I. Machuca‐Parra, Frédéric Paré, Mete Civelek, Weinian Shou, Gareth E. Lim   +6 more
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Adipogenesis [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine actions of various peptide and steroid hormones.
Kelesha, Sarjeant, Jacqueline M, Stephens   +1 more
openaire   +3 more sources

Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation

Molecules, 2022
Excessive storage of lipids in visceral or ectopic sites stimulates adipokine production, which attracts macrophages. This process determines the pro- and anti-inflammatory response regulation in adipose tissue during obesity-associated systemic ...
Pandurangan Subash-Babu, Hussah Mohammed Alowaidh, Laila Naif Al-Harbi, Ghalia Shamlan, Amal A. Aloud, Sahar Abdulaziz AlSedairy, Ali Abdullah Alshatwi   +6 more
doaj   +1 more source

Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes

Metabolites, 2023
Luteolin-7-O-rutinoside (lut-7-O-rutin), a flavonoid commonly present in Mentha longifolia L. and Olea europaea L. leaves has been used as a flavoring agent with some biological activity.
Pandurangan Subash-Babu, Sahar Abdulaziz AlSedairy, Manal Abdulaziz Binobead, Ali A. Alshatwi   +3 more
doaj   +1 more source

Prevalence of using herbs and natural products as a protective measure during the COVID-19 pandemic among the Saudi population: an online cross-sectional survey

Saudi Pharmaceutical Journal, 2021
Considering that no food or supplement has been authorised to prevent COVID-19, individuals continue to search for and consume specific herbs, foods and commercial supplements for this purpose.
Amna Abdullah Alotiby, Laila Naif Al-Harbi   +1 more
doaj   +1 more source