Results 21 to 30 of about 55,397 (143)

A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells

Adipocyte, 2022
Obesity has become a serious global public health problem; a deeper understanding of systemic change of chromatin accessibility during human adipogenesis contributes to conquering obesity and its related diseases.
Sen Li, Xiaolin Zong, Liheng Zhang, Luya Li, Jianxin Wu   +4 more
doaj   +1 more source

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

Scientific Reports, 2021
Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear.
Masanori Oshi, Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe   +7 more
doaj   +1 more source

Beneficial Fatty Acid Ratio of Salvia hispanica L. (Chia Seed) Potentially Inhibits Adipocyte Hypertrophy, and Decreases Adipokines Expression and Inflammation in Macrophage

Foods, 2020
The present study aimed to determine the role of Salvia hispanica L., (chia seed) fatty acid content in adipocyte lipid accumulation and human macrophage immunoregulatory potential.
Subash-Babu Pandurangan, Salah A. Al-Maiman, Laila Naif Al-Harbi, Ali A. Alshatwi   +3 more
doaj   +1 more source

METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia

FEBS Open Bio, 2021
Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display enhanced adipogenesis compared with bone marrow MSCs from healthy donors.
Zhi‐peng Pan, Bin Wang, Di‐yu Hou, Ruo‐lan You, Xiao‐ting Wang, Wen‐hui Xie, Hui‐fang Huang   +6 more
doaj   +1 more source

RNA-seq analysis reveals the critical role of the novel lncRNA BIANCR in intramuscular adipogenesis through the ERK1/2 signaling pathway

Journal of Animal Science and Biotechnology, 2023
Background Long non-coding RNAs (lncRNAs) regulate numerous biological processes, including adipogenesis. Research on adipogenesis will assist in the treatment of human metabolic diseases and improve meat quality in livestock, such as the content of ...
Xinhao Ma, Xinran Yang, Dianqi Zhang, Wenzhen Zhang, Xiaoyu Wang, Kuncheng Xie, Jie He, Chugang Mei, Linsen Zan   +8 more
doaj   +1 more source

Regulatory network of metformin on adipogenesis determined by combining high-throughput sequencing and GEO database

Adipocyte, 2022
Adipose differentiation and excessive lipid accumulation are the important characteristics of obesity. Metformin, as a classic hypoglycaemic drug, has been proved to reduce body weight in type 2 diabetes, the specific mechanism has not been completely ...
Zhicong Zhao, Chenxi Wang, Jue Jia, Zhaoxiang Wang, Lian Li, Xia Deng, Zhensheng Cai, Ling Yang, Dong Wang, Suxian Ma, Li Zhao, Zhigang Tu, Guoyue Yuan   +12 more
doaj   +1 more source

Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression

Scientific Reports, 2022
Adipogenesis is the process by which precursor cells, preadipocytes (preACs), differentiate into adipocytes (ACs). Here, we investigated differentially expressed miRNAs (DEMs) between the two conditions to understand the regulatory role of miRNAs in ...
Yerim Heo, Hyunjung Kim, Jiwon Lim, Sun Shim Choi   +3 more
doaj   +1 more source

Biphasic effects of FGF2 on adipogenesis. [PDF]

PLoS ONE, 2015
Although stem cells from mice deficient of FGF2 have been reported to display enhanced capacity for adipogenesis, the literature using in vitro cell culture system has so far reported conflicting results on the role of FGF2 in adipogenesis.
Sooho Kim, Chihoon Ahn, Naeun Bong, Senyon Choe, Dong Kun Lee   +4 more
doaj   +1 more source

Adipogenesis and WNT signalling [PDF]

Trends in Endocrinology & Metabolism, 2009
An inability of adipose tissue to expand consequent to exhausted capacity to recruit new adipocytes might underlie the association between obesity and insulin resistance. Adipocytes arise from mesenchymal precursors whose commitment and differentiation along the adipocytic lineage is tightly regulated.
Christodoulides, C, Lagathu, C, Sethi, J, Vidal-Puig, A   +3 more
openaire   +2 more sources

Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis. [PDF]

PLoS ONE, 2013
BACKGROUND: During mesenchymal stem cell (MSC) conversion into adipocytes, the adipogenic cocktail consisting of insulin, dexamethasone, indomethacin and 3-isobutyl-1-methylxanthine not only induces adipogenic-specific but also genes for non-adipogenic ...
Mujib Ullah, Stefan Stich, Thomas Häupl, Jan Eucker, Michael Sittinger, Jochen Ringe   +5 more
doaj   +1 more source