Results 101 to 110 of about 28,208 (288)

LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue

Frontiers in Endocrinology, 2018
Patients with obesity are susceptible to hypertension and diabetes. Over-activation of cannabinoid receptor 1 (CB1R) in adipose tissue is proposed in the pathophysiology of metabolic disorders, which led to the metabolic dysfunction of adipose tissue and
Ziqi Dong, Hui Gong, Yadan Chen, Hong Wu, Jun Wu, Yinghong Deng, Xinmao Song   +6 more
doaj   +1 more source

The Adipocyte and Adaptive Immunity

Frontiers in Immunology, 2020
Not only do Adipocytes have energy storage and endocrine functions, but they also play an immunological role. Adipocytes are involved in adaptive immunity to mediate the pathological processes of a variety of chronic inflammatory diseases and autoimmune ...
Jianfeng Song, Jianfeng Song, Tuo Deng, Tuo Deng, Tuo Deng   +4 more
doaj   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Fetuin-A is also an adipokine

Lipids in Health and Disease, 2019
Fetuin-A (FetA), which impairs insulin action is considered classically as a hepatokine. In patients with Metabolic Syndrome without the confounding of diabetes or cardiovascular diseases, we showed significant increases in both circulating and ...
I. Jialal, R. Pahwa
semanticscholar   +1 more source

Metabolic, inflammatory and adipokine differences on overweight/obese children with and without metabolic syndrome: A cross-sectional study

, 2023
Idalia Cura–Esquivel, Marlene Marisol Perales-Quintana, Liliana Torres-González, Katia Guzman Avilan, Linda E. Muñoz‐Espinosa, Paula Cordero‐Pérez   +5 more
openalex   +1 more source

The Effect of A 4-Week Vegan Diet on Adipokine Levels in Healthy Male and Female Participants: A Randomized-Controlled Trial [PDF]

, 2020
Ann‐Kathrin Lederer, Manuel Hettich, Roman Huber, Luciana Hannibal, Elena Neumann   +4 more
openalex   +1 more source

Symbolic regression analysis of interactions between first trimester maternal serum adipokines in pregnancies which develop pre-eclampsia [PDF]

, 2022
Casper Wilstrup, Paula L. Hedley, Line Rode, Sophie Placing, Karen R. Wøjdemann, A. C. Shalmi, Karin Sundberg, Michael Christiansen   +7 more
openalex   +1 more source

Adipokines and Insulin Resistance

Molecular Medicine, 2008
Obesity is associated with an array of health problems in adult and pediatric populations. Understanding the pathogenesis of obesity and its metabolic sequelae has advanced rapidly over the past decades. Adipose tissue represents an active endocrine organ that, in addition to regulating fat mass and nutrient homeostasis, releases a large number of ...
Katja, Rabe, Michael, Lehrke, Klaus G, Parhofer, Uli C, Broedl   +3 more
openaire   +2 more sources

Association between high serum ferritin and periodontitis: A population‐based cross‐sectional preliminary study

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study was to investigate the association between high serum ferritin levels and periodontitis considering pathways induced by sociodemographic and behavioral factors, serum inflammation, and metabolic risk. Methods Data from 7283 individuals who participated in the Third National Health and Nutrition Examination ...
Susilena Arouche Costa, Cecilia Cláudia Costa Ribeiro, Ana Regina Oliveira Moreira, Gustavo G. Nascimento, Soraia de Fátima Carvalho Souza   +4 more
wiley   +1 more source

Serum Adiponectin Is Elevated in Critically Ill Patients with Liver Disease and Associated with Decreased Overall Survival

Biomedicines
Background: Adiponectin, an adipokine with anti-inflammatory properties, has been implicated in various liver diseases. This study aimed to elucidate the prognostic value of serum adiponectin levels in critically ill patients with liver disease. Methods:
Maike R. Pollmanns, Qendrim Pajaziti, Philipp Hohlstein, Jule K. Adams, Samira Abu Jhaisha, Elena Kabak, Karim Hamesch, Sophie H. A. Nusser, Ralf Weiskirchen, Theresa H. Wirtz, Alexander Koch   +10 more
doaj   +1 more source