Results 1 to 10 of about 75,945 (288)

Adipokines in atherosclerosis: unraveling complex roles

open access: yesFrontiers in Cardiovascular Medicine, 2023
Adipokines are biologically active factors secreted by adipose tissue that act on local and distant tissues through autocrine, paracrine, and endocrine mechanisms.
Jiaying Luo   +7 more
doaj   +1 more source

Research progress on the role of adipokines in the pathogenesis of sarcopenia in the elderly [PDF]

open access: yesJichu yixue yu linchuang, 2023
The change of fat distribution, the decrease of physical activity and the influence of diseases during aging will change the circulating level of adipokines.
DANG Caihong, LI Weixin
doaj   +1 more source

Adipokines in pulmonary hypertension: angels or demons?

open access: yesHeliyon, 2023
Pulmonary hypertension (PH) is a devastating cardiopulmonary disorder with poor prognosis and limited curative options. Recent studies revealed a strong association between adipose tissue dysfunction (e.g., obesity) and PH.
Qi Jia   +5 more
doaj   +1 more source

Adipokines in Pregnancy: A Systematic Review of Clinical Data

open access: yesBiomedicines, 2023
Adipokines are signaling proteins involved in metabolic, endocrinological, vascular and immunogenic processes. Associations of various adipokines with not only insulin resistance but also with increased insulin sensitivity, increased systolic blood ...
Noura Kabbani   +6 more
doaj   +1 more source

Adipokines in Sleep Disturbance and Metabolic Dysfunction: Insights from Network Analysis

open access: yesClocks & Sleep, 2022
Adipokines are a growing group of secreted proteins that play important roles in obesity, sleep disturbance, and metabolic derangements. Due to the complex interplay between adipokines, sleep, and metabolic regulation, an integrated approach is required ...
Zhikui Wei, You Chen, Raghu P. Upender
doaj   +1 more source

Increased circulating ANG II and TNF-α represents important risk factors in obese Saudi adults with hypertension irrespective of diabetic status and BMI [PDF]

open access: yes, 2012
Central adiposity is a significant determinant of obesity-related hypertension risk, which may arise due to the pathogenic inflammatory nature of the abdominal fat depot.
A Berrington de Gonzalez   +63 more
core   +6 more sources

PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPAR?? at Ser273 [PDF]

open access: yes, 2020
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a master regulator of adipose tissue biology. In obesity, phosphorylation of PPAR gamma at Ser273 (pSer273) by cyclin-dependent kinase 5 (CDK5)/extracellular signal-regulated kinase (ERK ...
Choi, Jang Hyun   +11 more
core   +1 more source

MiRNAs as novel adipokines : obesity-related circulating MiRNAs influence chemosensitivity in cancer patients [PDF]

open access: yes, 2020
Adipose tissue is an endocrine organ, capable of regulating distant physiological processes in other tissues via the release of adipokines into the bloodstream.
Dewhurst, T   +3 more
core   +2 more sources

Adipokines as Clinically Relevant Therapeutic Targets in Obesity

open access: yesBiomedicines, 2023
Adipokines provide an outstanding role in the comprehensive etiology of obesity and may link adipose tissue dysfunction to further metabolic and cardiovascular complications.
Marleen Würfel   +6 more
doaj   +1 more source

Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma [PDF]

open access: yes, 2015
The prevalence of global obesity is increasing. Obesity is associated with general cancer-related morbidity and mortality and is a known risk factor for development of specific cancers.
Alfraidi, Albandri   +5 more
core   +5 more sources

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