ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri +5 more
wiley +1 more source
Summarizing the Role of Selected Adipokines in Parkinson's Disease: What Is Known About Leptin, Adiponectin, Resistin, Visfatin, and Progranulin in Neurodegeneration? [PDF]
Milanowski J +3 more
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an increasingly prevalent chronic liver condition that can progress to severe complications such as metabolic dysfunction‐associated steatohepatitis (MASH). Despite its growing burden, there are no reliable non‐invasive biomarkers for tracking disease progression.
Szu‐Jen Wang +9 more
wiley +1 more source
Human Peripancreatic Fat Secretome Impacts Local Pancreas Biology. [PDF]
Kashyap SR, Alonso LC.
europepmc +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Adipokines and Vascular Modulators in CKM: Emerging Biomarkers as Diagnostic and Therapeutic Targets. [PDF]
Gerdanovics CA +12 more
europepmc +1 more source
The Effect of Low Socioeconomic Status on the Leptin‐to‐Adiponectin Ratio
ABSTRACT Aim(s) To examine the relationship between low socioeconomic status, stress, and chronic disease risk, and to explore leptin and adiponectin as upstream biomarkers of inflammation to inform evidence‐based nursing practice and policy. Design Integrative literature review guided by evidence‐based practice and lifecourse theory.
Jamie Rausch +2 more
wiley +1 more source
Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways. [PDF]
Ali N.
europepmc +1 more source
Association of Obesity Severity With Cardiometabolic and Renal Disease Burden in the United States
ABSTRACT Objective This study examined the association between obesity severity and cardiometabolic and renal disease, using BMI as a surrogate for obesity severity. Methods This is a cross‐sectional study using data from the United States Behavioral Risk Factor Surveillance System (BRFSS), 2011–2023.
Florina Corpodean +7 more
wiley +1 more source
Genetic links between periodontal disease and circulating leptin and resistin: A Mendelian randomization study. [PDF]
Jing Y, Zhu J.
europepmc +1 more source

