Results 11 to 20 of about 373,606 (268)
Marine Drugs, 2018 We found previously that white adipose tissue (WAT) hyperplasia in obese mice was limited by dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA). Here we aimed to characterize the underlying mechanism.
Katerina Adamcova +7 more
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Crtc1 Deficiency Causes Obesity Potentially via Regulating PPARγ Pathway in White Adipose
Frontiers in Cell and Developmental Biology, 2021 Obesity is characterized by excessive fat accumulation and associated with glucose and lipid metabolism disorders. Crtc1, a transcription cofactor regulating CREB activity, has been involved in the pathogenesis of metabolic syndrome; however, the ...
Yimeng Hu +9 more
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Adipose-specific phospholipase as regulator of adiposity [PDF]
Nutrition Reviews, 2009 A white adipose-tissue-specific intracellular phospholipase, which releases arachidonic acid from position sn-2 of phospholipids, was recently discovered and named AdPLA. When AdPLA was induced by feeding or by insulin treatment, the arachidonic acid released from phospholipids acted as a precursor for the formation of prostaglandin E(2) (PGE(2 ...
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The genetics of adiposity [PDF]
Current Opinion in Genetics & Development, 2018 Genome-wide discovery efforts have identified more than 500 genetic loci associated with adiposity traits. The vast majority of these loci were found through large-scale meta-analyses for body mass index (BMI) and waist-to-hip ratio (WHR), and in European ancestry populations.
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Frontiers in Physiology, 2018 Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic regimen of regular exercise and pharmaceutical treatment is often recommended for their clinical management.
Luana G. Leal +4 more
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Applied Sciences, 2021 Ultrasound measurement of adipose tissue offers an alternative measure of body composition with less technical skill requirement than skinfolds. However, the relationship between skinfold and ultrasound measurements of adipose tissue is uncertain.
Helen Ryan-Stewart +4 more
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Frontiers in Immunology, 2018 Adipose tissue is a metabolic organ that plays a central role in controlling systemic energy homeostasis. Compelling evidence indicates that immune system is closely linked to healthy physiologic functions and pathologic dysfunction of adipose tissue. In
Yoon Jeong Park +8 more
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Diabetes Care, 2002 At a symposium titled “Adipose Tissue as a Secretory Organ” at the American Diabetes Association (ADA), San Francisco, June 2002, Jeffrey Flier (Boston, MA) discussed the effects of visceral obesity. While reviewing the differing components of the metabolic syndrome, which to large extent are driven by insulin resistance, he asked, “Where does the ...
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The impact of poor metabolic health on aggressive breast cancer: adipose tissue and tumor metabolism
Frontiers in Endocrinology, 2023 Obesity and type 2 diabetes are chronic metabolic diseases that impact tens to hundreds of millions of adults, especially in developed countries.
Barbara Mensah Sankofi +9 more
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Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation
Nature Communications, 2017 VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin +10 more
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