Results 41 to 50 of about 519,569 (305)

Reconstituted high-density lipoprotein infusion modulates fatty acid metabolism in patients with type 2 diabetes mellitus

Journal of Lipid Research, 2011
We recently demonstrated that reconstituted high-density lipoprotein (rHDL) modulates glucose metabolism in humans via both AMP-activated protein kinase (AMPK) in muscle and by increasing plasma insulin.
Brian G. Drew, Andrew L. Carey, Alaina K. Natoli, Melissa F. Formosa, Donna Vizi, Medini Reddy-Luthmoodoo, Jacquelyn M. Weir, Christopher K. Barlow, Gerrit van Hall, Peter J. Meikle, Stephen J. Duffy, Bronwyn A. Kingwell   +11 more
doaj   +1 more source

The adipose organ: morphological perspectives of adipose tissues [PDF]

Proceedings of the Nutrition Society, 2001
Anatomically, an organ is defined as a series of tissues which jointly perform one or more interconnected functions. The adipose organ qualifies for this definition as it is made up of two tissue types, the white and brown adipose tissues, which collaborate in partitioning the energy contained in lipids between thermogenesis and the other metabolic ...
openaire   +2 more sources

Adipose Tissue Inflammation

Cells, 2023
In recent decades, obesity has become one of the most common metabolic diseases [...]
openaire   +4 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]

, 2010
Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
McKinnon, E., Nolan, D., Hammond, E.L.
core  

Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation

eLife, 2017
Beige/brite adipocytes are induced within white adipose tissues (WAT) and, when activated, consume glucose and fatty acids to produce heat. Classically, two stimuli have been used to trigger a beiging response: cold temperatures and β3-adrenergic ...
Yuwei Jiang, Daniel C Berry, Jonathan M Graff   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Refinements in adipose tissue biopsy collection in shorebirds: effect on pain, wound healing, and mass gain

Journal of Field Ornithology, 2023
Non-lethal methods to sample adipose tissues from fat depots in small birds are highly valuable as a time integrated sample matrix for ecotoxicology and ecophysiology research.
Christy Morrissey, Kurtis Swekla
doaj  

Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues

Particle and Fibre Toxicology, 2011
Background Prior studies have demonstrated a link between air pollution and metabolic diseases such as type II diabetes. Changes in adipose tissue and its mitochondrial content/function are closely associated with the development of insulin resistance ...
Harkema Jack R, Wang Aixia, Yang Yifeng, Bramble Lori A, Wagner James G, Lewandowski Ryan P, Hotchkiss Ian P, Zhong Mianhua, Xu Xiaohua, Xu Zhaobin, Lippmann Morton, Rajagopalan Sanjay, Chen Lung-Chi, Sun Qinghua   +13 more
doaj   +1 more source

Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors

New England Journal of Medicine, 2011
Obesity in childhood is associated with increased cardiovascular risk. It is uncertain whether this risk is attenuated in persons who are overweight or obese as children but not obese as adults.We analyzed data from four prospective cohort studies that measured childhood and adult body-mass index (BMI, the weight in kilograms divided by the square of ...
Juonala, M, Magnussen, CG, Berenson, GS, Venn, A, Burns, TL, Sabin, MA, Srinivasan, SR, Daniels, SR, Davis, PH, Chen, W, Sun, C, Cheung, M, Viikari, JSA, Dwyer, T, Raitakari, OT   +14 more
openaire   +5 more sources