Results 51 to 60 of about 373,606 (268)

Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress[S]

open access: yesJournal of Lipid Research, 2013
Fat-specific protein 27 (FSP27), a member of the cell death-inducing DNA fragmentation factor α-like effector (Cide) family, is highly expressed in adipose tissues and is a lipid droplet (LD)-associated protein that induces the accumulation of LDs. Using
Masami Ueno   +5 more
doaj   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park   +7 more
wiley   +1 more source

TULP3 Regulates Proliferation and Differentiation of 3T3-L1 Preadipocytes Through the Hedgehog Signaling Pathway

open access: yesBiology
The TULP family was first identified in progressively obese mice, and TULP3, as a member of its family, has been much studied in tumor cells, but studies on its role in adipocytes have not yet been reported.
Xinlin Jin   +8 more
doaj   +1 more source

Leptogenic effects of NAPE require activity of NAPE-hydrolyzing phospholipase D

open access: yesJournal of Lipid Research, 2017
Food intake induces synthesis of N-acylphosphatidylethanolamines (NAPEs) in the intestinal tract. While NAPEs exert leptin-like (leptogenic) effects, including reduced weight gain and food intake, the mechanisms by which NAPEs induce these leptogenic ...
Zhongyi Chen   +7 more
doaj   +1 more source

Adipose‐derived mesenchymal stem cells differentiate into pancreatic cancer‐associated fibroblasts in vitro

open access: yesFEBS Open Bio, 2020
Cancer‐associated fibroblasts (CAFs) are key components of the dense, proliferating stroma observed in pancreatic ductal adenocarcinoma (PDAC), and CAF subpopulations drive tumor heterogeneity and play a major role in PDAC progression and drug resistance.
Yoshihiro Miyazaki   +3 more
doaj   +1 more source

Generation of Bone Tissue Using Adipose Tissue-derived Stem Cells

open access: yesBezmiâlem Science, 2021
Objective:Bone grafts and even bone substitutes do not meet all of the requirements of bony reconstructions. The aim of this study was to generate bone tissue from autologous adipose tissue-derived mesenchymal stem cells (ATDMSCs) and decellularised bone
Emre Gönenç BAYGÖL   +8 more
doaj   +1 more source

Overall Adiposity, Adipose Tissue Distribution, and Endometriosis [PDF]

open access: yesNursing Research, 2016
Endometriosis has been associated with a lean body habitus. However, we do not understand whether endometriosis is also associated with other characteristics of adiposity, including adipose tissue distribution and amount of visceral adipose tissue (VAT; adipose tissue lining inner organs).
Backonja, Uba   +2 more
openaire   +3 more sources

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome

open access: yesFrontiers in Immunology, 2018
Background and aims: Chronic ethanol exposure results in inflammation in adipose tissue; this response is associated with activation of complement as well as the development of alcohol-related liver disease (ALD).
Rebecca L. McCullough   +6 more
doaj   +1 more source

Adiposity is associated with DNA methylation profile in adipose tissue [PDF]

open access: yesInternational Journal of Epidemiology, 2014
Adiposity is a risk factor for type 2 diabetes and cardiovascular disease, suggesting an important role for adipose tissue in the development of these conditions. The epigenetic underpinnings of adiposity are not well understood, and studies of DNA methylation in relation to adiposity have rarely focused on target adipose tissue.
Golareh, Agha   +5 more
openaire   +2 more sources

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