Results 21 to 30 of about 373,606 (268)

LLC tumor cells-derivated factors reduces adipogenesis in co-culture system

open access: yesHeliyon, 2018
Cancer cachexia (CC) is a multifactorial syndrome with an unknown etiology. The primary symptom is the progressive reduction of the body weight. Recently, down-regulation of adipogenic and lipogenic genes were demonstrated to be early affected during ...
Magno Alves Lopes   +4 more
doaj   +1 more source

An Exploratory Analysis of the Role of Adipose Characteristics in Fulltime Wheelchair Users’ Pressure Injury History

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Aim: The goals of this study were 1) to identify the relationship between adipose (subcutaneous and intramuscular) characteristics and pressure injury (PrI) history in wheelchair users and 2) to identify subject characteristics, including biomechanical ...
Sharon Eve Sonenblum   +5 more
doaj   +1 more source

The antifibrotic adipose‐derived stromal cell: Grafted fat enriched with CD74+ adipose‐derived stromal cells reduces chronic radiation‐induced skin fibrosis

open access: yesStem Cells Translational Medicine, 2020
Fat grafting can reduce radiation‐induced fibrosis. Improved outcomes are found when fat grafts are enriched with adipose‐derived stromal cells (ASCs), implicating ASCs as key drivers of soft tissue regeneration.
Mimi R. Borrelli   +13 more
doaj   +1 more source

Atlas of Fshr expression from novel reporter mice

open access: yeseLife
The FSH-FSHR pathway has been considered an essential regulator in reproductive development and fertility. But there has been emerging evidence of FSHR expression in extragonadal organs.
Hongqian Chen   +10 more
doaj   +1 more source

Macrophages Mediate Increased CD8 T Cell Inflammation During Weight Loss in Formerly Obese Mice

open access: yesFrontiers in Endocrinology, 2020
Even after successful weight reduction, obese adults tend to quickly regain the lost weight. This raises the question of whether weight loss improves the underlying chronic adipose tissue inflammation characteristic of obesity.
Jayagopi Surendar   +6 more
doaj   +1 more source

SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding

open access: yesNature Communications, 2016
The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang   +11 more
doaj   +1 more source

miRNAs in Adipocyte-Derived Extracellular Vesicles: Multiple Roles in Development of Obesity-Associated Disease

open access: yesFrontiers in Molecular Biosciences, 2020
Obesity and overweight are common modern health challenges. Caloric intake greater than that needed for energy production results in excess storage of fat in the abdomen.
Yaliang Zhou, Chunlu Tan
doaj   +1 more source

Parallels in Immunometabolic Adipose Tissue Dysfunction with Ageing and Obesity

open access: yesFrontiers in Immunology, 2018
Ageing, like obesity, is often associated with alterations in metabolic and inflammatory processes resulting in morbidity from diseases characterised by poor metabolic control, insulin insensitivity, and inflammation.
William Trim   +2 more
doaj   +1 more source

Adipose Tissue Inflammation

open access: yesCells, 2023
In recent decades, obesity has become one of the most common metabolic diseases [...]
openaire   +4 more sources

Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans

open access: yesFrontiers in Cardiovascular Medicine, 2023
IntroductionVascular dysfunction and chronic inflammation are characteristics of obesity-induced adipose tissue dysfunction. Proinflammatory cytokines can drive an endothelial-to-mesenchymal transition (EndoMT), where endothelial cells undergo a ...
Nicholas W. Chavkin   +10 more
doaj   +1 more source

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