Results 21 to 30 of about 519,569 (305)
Frontiers in Immunology, 2018 Adipose tissue is a metabolic organ that plays a central role in controlling systemic energy homeostasis. Compelling evidence indicates that immune system is closely linked to healthy physiologic functions and pathologic dysfunction of adipose tissue. In
Yoon Jeong Park +8 more
doaj +1 more source
mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]
, 2016 Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Handschin, Christoph +20 more
core +1 more source
The impact of poor metabolic health on aggressive breast cancer: adipose tissue and tumor metabolism
Frontiers in Endocrinology, 2023 Obesity and type 2 diabetes are chronic metabolic diseases that impact tens to hundreds of millions of adults, especially in developed countries.
Barbara Mensah Sankofi +9 more
doaj +1 more source
Diabetes Care, 2002 At a symposium titled “Adipose Tissue as a Secretory Organ” at the American Diabetes Association (ADA), San Francisco, June 2002, Jeffrey Flier (Boston, MA) discussed the effects of visceral obesity. While reviewing the differing components of the metabolic syndrome, which to large extent are driven by insulin resistance, he asked, “Where does the ...
openaire +2 more sources
Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation
Nature Communications, 2017 VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin +10 more
doaj +1 more source
LLC tumor cells-derivated factors reduces adipogenesis in co-culture system
Heliyon, 2018 Cancer cachexia (CC) is a multifactorial syndrome with an unknown etiology. The primary symptom is the progressive reduction of the body weight. Recently, down-regulation of adipogenic and lipogenic genes were demonstrated to be early affected during ...
Magno Alves Lopes +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Aim: The goals of this study were 1) to identify the relationship between adipose (subcutaneous and intramuscular) characteristics and pressure injury (PrI) history in wheelchair users and 2) to identify subject characteristics, including biomechanical ...
Sharon Eve Sonenblum +5 more
doaj +1 more source
Stem Cells Translational Medicine, 2020 Fat grafting can reduce radiation‐induced fibrosis. Improved outcomes are found when fat grafts are enriched with adipose‐derived stromal cells (ASCs), implicating ASCs as key drivers of soft tissue regeneration.
Mimi R. Borrelli +13 more
doaj +1 more source
Adipose Tissue as an Endocrine Organ [PDF]
, 2018 As one of the largest endocrine organs in the body, adipose tissue secrets a number of bioactive hormones, called adipokines. The expression and secretion of adipokines are tightly controlled and coordinated by physiological and pathophysiological ...
Feng, T, Hui, X
core +1 more source
Atlas of Fshr expression from novel reporter mice
eLifeThe FSH-FSHR pathway has been considered an essential regulator in reproductive development and fertility. But there has been emerging evidence of FSHR expression in extragonadal organs.
Hongqian Chen +10 more
doaj +1 more source