Results 211 to 220 of about 21,384 (315)

Vaccination with synthetic long peptide and CpG 2395 in AddaVax induces potent anti-tumor effects. [PDF]

Exp Biol Med (Maywood)
Jiang S, Zhao S, Zhao Q, Wang Y, Zhang W, Feng Y, Zhang L.   +6 more
europepmc   +1 more source

Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer

Head &Neck, EarlyView.
ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with a 20% recurrence rate. Bitter taste receptors (T2Rs) and their genes (TAS2Rs) may regulate survival in solid tumors. This study examined T2R expression and function in PTC cells.
Kimberly Wei, Brianna L. Hill, Joel C. Thompson, Zoey A. Miller, Arielle Mueller, Robert J. Lee, Ryan M. Carey   +6 more
wiley   +1 more source

Harnessing adjuvant-induced epigenetic modulation for enhanced immunity in vaccines and cancer therapy. [PDF]

Front Immunol
Megdiche Y, Salerno-Gonçalves R.
europepmc   +1 more source

Detection of PTEN Mutations in Fine Needle Aspiration Biopsies of Indeterminate Thyroid Nodules: Impact on Diagnosis and Prognosis

Head &Neck, EarlyView.
ABSTRACT Background Data connecting PTEN mutations with thyroid cancer risk for indeterminate nodules remain limited due to the rare nature of these mutations. The aim of this study was to determine the relationship between PTEN mutations identified in cytologically indeterminate nodules and final pathology and clinical outcomes.
Lauren E. Schlegel, Madelaine Brill‐Edwards, Zi‐Xuan Wang, Christopher McNair, Stacey Gargano, Elizabeth Cottrill   +5 more
wiley   +1 more source

Intradermal Injection of a Protein Alone Without Additional Adjuvants Using a Needle-Free Pyro-Drive Jet Injector Induces Potent CD8⁺ T Cell-Mediated Antitumor Immunity. [PDF]

Int J Mol Sci
Sonoda J, Mizoguchi I, Yamaguchi N, Horio E, Miyakawa S, Xu M, Yoneto T, Katahira Y, Hasegawa H, Hasegawa T, Yamashita K, Yoshimoto T.   +11 more
europepmc   +1 more source

Combined Tumor Infiltrating Lymphocytes and PD‐L1 Status in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objectives To determine if the assessment of CD8+ tumor‐infiltrating lymphocytes (TILs) adds prognostic information to the PD‐L1 combined positive score (CPS) in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Methods A retrospective case series was performed of 77 patients with R/M HNSCC between 2003 and 2019.
Catherine T. Haring, Joshua D. Smith, Sarah M. Dermody, Jonathan B. McHugh, William R. Perry, Collin Brummel, Matthew E. Spector, J. Chad Brenner, Paul L. Swiecicki   +8 more
wiley   +1 more source

Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines. [PDF]

Sci Adv
Meany EL, Klich JH, Jons CK, Mao T, Chaudhary N, Utz A, Baillet J, Song YE, Saouaf OM, Ou BS, Williams SC, Eckman N, Irvine DJ, Appel E.   +13 more
europepmc   +1 more source

Prospective Registry Trial of Adjuvant High‐Dose Rate Brachytherapy in Unirradiated Head and Neck Cancer: 20‐Year Data

Head &Neck, EarlyView.
ABSTRACT Background and Purpose Full‐dose postoperative external beam radiation therapy (EBRT)/chemoradiation is the standard of care in patients with resected, unirradiated head and neck cancer (HNC). This study aims to determine the long‐term results of adjuvant high‐dose rate (HDR) brachytherapy ± intermediate‐dose postoperative external beam ...
Alejandro García‐Consuegra, Marta Gimeno‐Morales, Mauricio Cambeiro, José María López‐Picazo, Juan Alcalde, Luis I Ramos, Luca Tagliaferri, José Luis Guinot, Francesco Bussu, Marta Moreno‐Jiménez, Rafael Martinez‐Monge   +10 more
wiley   +1 more source

Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype. [PDF]

Viruses
Zhang S, Tang J, Liu L, Wei H, Xin L, Xiao K, Xiao J, Dong J, Li Z, Bai H, Wang S, Zhu W, Yang L, Zou S, Wang D.   +14 more
europepmc   +1 more source

Bilateral Thyroid Ima Arteries Arising From the Brachiocephalic Trunk: A First Case Report

Head &Neck, EarlyView.
ABSTRACT Rationale Bilateral thyroid ima artery (TIA) arising from the brachiocephalic trunk is an extremely rare anatomical variation, with no prior cases reported. Recognizing such vascular anomalies is crucial for optimizing surgical outcomes in thyroid and mediastinal procedures, as failure to identify these variations can lead to severe ...
Ziqiang Wang, Deguang Zhang, Qiwei Du, Weijun Zhang, Nian Liu, Rongguo Li   +5 more
wiley   +1 more source