Results 81 to 90 of about 21,002 (290)
Introduction: Subacute thyroiditis (SAT) is an inflammatory disease that has different trigger factors. Recent studies show the possible role of COVID-19 vaccine-induced thyroiditis in its initiation.
Vahid Reisi-Vanani+5 more
doaj
Adjuvant formulation for veterinary vaccines: Montanide™ Gel safety profile [PDF]
Selecting the adjuvant is one of the key for the success of the vaccine in the field. Selecting a flexible adjuvant that will fit with several vaccines dedicated to one or more animal species is a source of economical efficiency. Frequently the safety or
Parker, R.+4 more
core +1 more source
Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen+8 more
wiley +1 more source
Vaccine Development against the Renin-Angiotensin System for the Treatment of Hypertension
Hypertension is a global public health issue and the most important preventable cause of cardiovascular diseases. Despite the clinical availability of many antihypertensive drugs, many hypertensive patients have poor medication adherence and blood ...
Tatsuhiko Azegami, Hiroshi Itoh
doaj +1 more source
Apesar de relativamente recente, nota-se um acúmulo crescente e robusto de evidências experimentais e clínicas que apontam um estado gradativo de ativação imune-inflamatória em pacientes com insuficiência cardíaca (IC).
Angelo Michele de Candia+2 more
doaj +1 more source
Carbohydrate—protein conjugate vaccines [PDF]
Various pathogenic bacteria have coats of polysaccharide, many with repeating epitopes. Though polysaccharide vaccines have been available for some time, they induce mainly IgM production, and are only moderately protective in adults and ineffective in ...
Ada, G., Isaacs, D.
core +1 more source
Engineered Tissue Models to Decode Host–Microbiota Interactions
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio+5 more
wiley +1 more source
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang+5 more
wiley +1 more source
Adverse events of vaccines and the consequences of non-vaccination: a critical review
OBJECTIVE: To analyze the risks related to vaccines and the impacts of non-vaccination on the world population. METHODS: This is a narrative review that has considered information present in the bibliographic databases NCBI-PubMed, Medline, Lilacs, and ...
Luana Raposo de Melo Moraes Aps+5 more
doaj +1 more source
Particulate carriers as immunological adjuvants [PDF]
In recent years, much interest has focused on the significance of inducing not only systemic immunity but also good local immunity at susceptible mucosal surfaces. A new field of mucosal immunity has been established as information accumulates on gut-associated lymphoid tissue, bronchus-associated lymphoid tissue and nasal-associated lymphoid tissue ...
openaire +1 more source