Results 81 to 90 of about 14,767 (273)

Resposta sorológica de coelhos imunizados com antígenos de Pythium insidiosum associados a diferentes adjuvantes Serological response in rabbits immunized with Pythium insidiosum antigens associated with different adjuvants

Ciência Rural, 2002
O Pythium insidiosum é um fungo zoospórico que se desenvolve em locais alagadiços e que pode infectar humanos e animais, principalmente eqüinos. A infecção natural nesta espécie resulta em pitiose clínica, uma doença granulomatosa de difícil tratamento ...
Alexandre Trindade Leal, Janio Morais Santurio, Adriana Bardemaker Monteiro Leal, Alexandre Machado Pinto, Josiane Griebeler, Eduardo Furtado Flores, Laerte Ferreiro, João Batista Catto   +7 more
doaj   +1 more source

Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates.

PLoS ONE, 2020
Development of a successful HIV vaccine is dependent upon a determination of the optimum antigen and adjuvant as well as choosing an optimal site for vaccine delivery.
Bridget S Fisher, Nicholas Dambrauskas, Olesya Trakhimets, Daniela V Andrade, Jeremy Smedley, Donald L Sodora, D Noah Sather   +6 more
doaj   +1 more source

Principal causal effect identification and surrogate endpoint evaluation by multiple trials [PDF]

arXiv, 2015
Principal stratification is a causal framework to analyze randomized experiments with a post-treatment variable between the treatment and endpoint variables. Because the principal strata defined by the potential outcomes of the post-treatment variable are not observable, we generally cannot identify the causal effects within principal strata. Motivated
arxiv  

A Generation Method of Immunological Memory in Clonal Selection Algorithm by using Restricted Boltzmann Machines [PDF]

, 2018
Recently, a high technique of image processing is required to extract the image features in real time. In our research, the tourist subject data are collected from the Mobile Phone based Participatory Sensing (MPPS) system. Each record consists of image files with GPS, geographic location name, user's numerical evaluation, and comments written in ...
arxiv   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

The effect of exercise training on endothelial function in postmenopausal women with breast cancer under aromatase inhibitor therapy

Cancer Medicine, Volume 11, Issue 24, Page 4946-4953, December 2022., 2022
Exercise training led to significantly greater improvement in exercise capacity in postmenopausal women with aromatase inhibitor‐treated breast cancer than exercise counseling only, none the less it did not exert any measurable effects on endothelial dysfunction Abstract Background Breast cancer is the leading non‐cardiovascular cause of death in women.
Barbara Mayr, Bernhard Reich, Richard Greil, Josef Niebauer   +3 more
wiley   +1 more source

Current status and future prospects for the development of substance abuse vaccines

Expert Review of Vaccines, 2017
Introduction: Substance use disorders (SUD) are a significant threat to both individual and public health. To date, SUD pharmacotherapy has focused primarily on agonist medications (i.e.
R. David Heekin, Daryl Shorter, Thomas R. Kosten   +2 more
doaj   +1 more source

Novel digital tissue phenotypic signatures of distant metastasis in colorectal cancer [PDF]

arXiv, 2018
Distant metastasis is the major cause of death in colorectal cancer (CRC). Patients at high risk of developing distant metastasis could benefit from appropriate adjuvant and follow-up treatments if stratified accurately at an early stage of the disease.
arxiv  

Cryo‐EM Analysis of a Tri‐Heme Cytochrome‐Associated RC‐LH1 Complex from the Marine Photoheterotrophic Bacterium Dinoroseobacter Shibae

Advanced Science, EarlyView.
Cryo‐EM reveals a closed 17‐subunit LH ring encircling the RC‐LH1 complex in Dinoroseobacter shibae, featuring a novel helix‐turn‐helix subunit bridging RC and LH. Mg2⁺/Ca2⁺ stabilizes the complex, while periplasmic Cyt c₂ mediates electron transfer via a tri‐heme Cyt to the special pair of bacteriochlorophylls. Insights into energy/electron efficiency
Weiwei Wang, Yanting Liu, Jiayi Gu, Shaoya An, Cheng Ma, Haichun Gao, Nianzhi Jiao, Jian‐Ren Shen, John Thomas Beatty, Michal Koblížek, Xing Zhang, Qiang Zheng, Jing‐Hua Chen   +12 more
wiley   +1 more source

Tumor‐Adhesive Chitosan‐Derived Multi‐Immune Agonist Unleashes Strong and Durable Anti‐Cancer Immunity

Advanced Science, EarlyView.
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
Huilan He, Liang Liu, Yun Zheng, Jinlong Ji, Li Cao, Chunlian Ye, Yu Sun, Ying Zhang, Zhiyuan Zhong   +8 more
wiley   +1 more source