Results 91 to 100 of about 30,899 (248)

artikel adm

open access: yes, 2020
Keberhasilansuatupendidikantidakhanyadilihatdarimanajemenkelas, kurikulum, murid dan sebagainya, tetapi juga manajemen personalia ikutberperandalamkeberhasilansuatupendidikan. Makadiperlukanmanajemen personalia (PTK). Dalampenelitianiniditemukanbahwaadatigaproses administrasi PTK yaitupenggandaan, penetapan, dan pembinaan.
openaire   +2 more sources

Does Next Generation Sequencing (NGS)‐Based CYP2D6 Sequencing Improve Genotype–Phenotype Concordance in Tamoxifen‐Treated Patients?

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
CYP2D6 metabolizes about 20% of commonly used drugs, including tamoxifen, a major hormone therapy for breast cancer. Although the relationship between tamoxifen pharmacokinetics and CYP2D6 genotype has been demonstrated, residual variability in drug exposure remains unexplained.
Jeanne Petit   +7 more
wiley   +1 more source

IN VITRO ADME STUDIES OF TUG-891, A GPR-120 INHIBITOR USING SWISS ADME PREDICTOR

open access: yes, 2019
Predicting the absorption, distribution, metabolism and elimination (ADME) profile of drug candidates before their synthesis, in the early stage of drug discovery, could help in selecting candidates with the less critical ADME profile.
Dahima, Rashmi, Mishra, Shweta
core   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini   +4 more
wiley   +1 more source

In silico ADME/toxicity analysis.

open access: yes, 2013
In silico ADME/toxicity analysis.
Gabriela Mustata (257653)   +10 more
core   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

早期ADME特征在CYP3A4探针发现中的关键作用

open access: yes, 2012
Early ADME properties for discovery of human in vivo ...
杨凌
core  

Conference Report: The importance of HT-ADME in drug discovery

open access: yes, 2011
The inaugural meeting of the Boston Society High-Throughput Absorption, Distribution, Metabolism and Excretion (HT-ADME) Conference was held in Cambridge, MA (USA).
Daniel Morgan
core   +1 more source

adm proses

open access: yes, 2020
Teknik dan proses adalah dua hal yang tidak bisa dilepaskan dalam upaya pencapaian suatu yang diinginkan dalam supervise pendidikan. Proses supervisi merupakan rangkaian kagiatan yang dilaksanakan ketika melakukan supervisi. Secara umum proses pelaksanaan supervisi dilaksanakan melalui tiga tahapan yakni tahpan perencanaan, pelaksanaan, evaluasi dan ...
openaire   +2 more sources

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