Results 91 to 100 of about 30,899 (248)
Keberhasilansuatupendidikantidakhanyadilihatdarimanajemenkelas, kurikulum, murid dan sebagainya, tetapi juga manajemen personalia ikutberperandalamkeberhasilansuatupendidikan. Makadiperlukanmanajemen personalia (PTK). Dalampenelitianiniditemukanbahwaadatigaproses administrasi PTK yaitupenggandaan, penetapan, dan pembinaan.
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CYP2D6 metabolizes about 20% of commonly used drugs, including tamoxifen, a major hormone therapy for breast cancer. Although the relationship between tamoxifen pharmacokinetics and CYP2D6 genotype has been demonstrated, residual variability in drug exposure remains unexplained.
Jeanne Petit +7 more
wiley +1 more source
IN VITRO ADME STUDIES OF TUG-891, A GPR-120 INHIBITOR USING SWISS ADME PREDICTOR
Predicting the absorption, distribution, metabolism and elimination (ADME) profile of drug candidates before their synthesis, in the early stage of drug discovery, could help in selecting candidates with the less critical ADME profile.
Dahima, Rashmi, Mishra, Shweta
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Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
In silico ADME/toxicity analysis.
In silico ADME/toxicity analysis.
Gabriela Mustata (257653) +10 more
core +1 more source
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley +1 more source
Conference Report: The importance of HT-ADME in drug discovery
The inaugural meeting of the Boston Society High-Throughput Absorption, Distribution, Metabolism and Excretion (HT-ADME) Conference was held in Cambridge, MA (USA).
Daniel Morgan
core +1 more source
Teknik dan proses adalah dua hal yang tidak bisa dilepaskan dalam upaya pencapaian suatu yang diinginkan dalam supervise pendidikan. Proses supervisi merupakan rangkaian kagiatan yang dilaksanakan ketika melakukan supervisi. Secara umum proses pelaksanaan supervisi dilaksanakan melalui tiga tahapan yakni tahpan perencanaan, pelaksanaan, evaluasi dan ...
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