Results 111 to 120 of about 50,348 (248)

SWEEPFINDER2: Increased sensitivity, robustness, and flexibility

, 2015
SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael, Hellmann, Ines, Huber, Christian D., Hubisz, Melissa J., Nielsen, Rasmus   +4 more
core   +1 more source

G2-manifolds and the ADM formalism [PDF]

Differential Geometry and its Applications, 2019
In this paper we study a Hamiltonian function on the cotangent bundle of the space of Riemannian metrics on a 3-manifold $M$ and prove the orbits of the constrained Hamiltonian dynamical system correspond to $G_2$-manifolds foliated by hypersurfaces diffeomorphic to $M\times \mathrm{SO}(3)$.
openaire   +3 more sources

Cardioprotective effect of spirulina on cafeteria diet‐induced cardiac injury in silico and in vivo study

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4720-4743, June 2026.
Abstract BACKGROUND Obesity is a major risk factor for cardiovascular disease, primarily due to its effects on lipid metabolism, oxidative stress, and inflammation. The aim of this study was to evaluate the effects of spirulina (SP) on cafeteria diet (CD)‐induced myocardial oxidative stress and inflammation using biochemical, histological, and in ...
Fatma Arrari, Mohamed‐Amine Jabri, Imen Hammami, Hichem Sebai   +3 more
wiley   +1 more source

2-Hidroksinaftaldehit Pentaflorofenil Hidrazon Bileşiğinin Sentezi, Karakterizasyonu ve Silico ADME Çalışmaları

Gazi Üniversitesi Fen Bilimleri Dergisi
Bu çalışmada pentaflorofenil hidrazin ile 2-hidroksi-naftaldehit bileşiklerinin kondenzasyon tepkimesi sonucu 2-hidroksi-naftaldehit pentaflorofenilhidrazon Schiff bazı sentezlendi.
Fatma Hamurcu
doaj   +1 more source

adm keuangan

, 2020
Dari beberapa kegiatan administrasi pendidikan, kegiatan yang menjadi salah satu unsur penting adalah Administrasi Anggaran/Biaya Pendidikan. Karena Biaya pendidikan merupakan salah satu komponen masukan instrumental (instrumental input) yang sangat penting dalam penyelenggaraan pendidikan (disekolah).
openaire   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Tugas ADM

, 2019
pentingnya sarana dan prasarana dalam ...
openaire   +14 more sources

adm konsep

, 2020
Administrasipendidikanmerupakan salah satubagiandari dunia pendidikankhususnya di lingkungansekolah. Administrasipendidikandiperlukandikarenakanadministrasipendidikanadalah proses memanfaatkan sumber daya pendidikan melalui kerja sama sejumlah orang dengan melaksanakan fungsi perencanaan, pelaksanaan, dan evaluasi, untuk mencapai ...
openaire   +2 more sources

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

British Journal of Pharmacology, Volume 183, Issue 12, Page 3377-3394, June 2026.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand, Simone Brogi, Mustafa Tezeren, Andrea Tafi, Omer H. Ocak, Hasan Koyuncu, Igor Tetko, Laurent Désaubry, Canan G. Nebigil   +8 more
wiley   +1 more source

Physiologically based pharmacokinetic and toxicokinetic modeling: A multidisciplinary approach to drug development and ecotoxicology [PDF]

Hospital Pharmacology
Introduction: Physiologically based pharmacokinetic (PBPK) modeling is a powerful tool in pharmaceutical research and drug development, offering accurate predictions of drug absorption, distribution, metabolism, and elimination (ADME).
Todorović Nemanja B., Ćoškov Aleksandra D., Andrić Nebojša Lj., Stanić Bojana Đ., Milijašević Boris Ž., Milošević Nataša P., Janković Slobodan M., Lalić-Popović Mladena N.   +7 more
doaj   +1 more source