Results 101 to 110 of about 24,681 (243)
Analytical Science Advances, Volume 7, Issue 2, December 2026.ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo +3 more
wiley +1 more source
, 2020 Pendidikan sebagaisebuahusahasadar dan terencanadalammewujudkansuasanabelajar dan proses pembelajaran agar pesertadidiksecaraaktifmengembangkanpotensidirinya, tentunyaharusmempunyaisuatupengorganisasian yang baik. Salah satu komponen guna menciptakan pengorganisasian tersebut haruslah ada sosok pemimpin.
openaire +2 more sources
Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu +6 more
wiley +1 more source
Biology, Medicine & Natural Product ChemistryDespite the efficacy of antihypertensive medications like ARBs, their adverse effects frequently result in suboptimal adherence. This study investigates the efficacy of flavonoids obtained from herbal sources as natural substitutes for traditional ...
Amir Thalib, Irma Putri Damayanti
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 731-744, September 2026.CYP2D6 metabolizes about 20% of commonly used drugs, including tamoxifen, a major hormone therapy for breast cancer. Although the relationship between tamoxifen pharmacokinetics and CYP2D6 genotype has been demonstrated, residual variability in drug exposure remains unexplained.
Jeanne Petit +7 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 34, 17 August 2026.A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Alexander M. Stephens +9 more
wiley +2 more sources
From Executor to Orchestrator: The Pharmacology Scientist in the Age of Agentic AI
Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 648-662, September 2026.Drug development productivity has not improved despite five decades of computational advancement, with the probability that a compound entering Phase I achieving regulatory approval remaining near 10%. Each automation wave increased throughput while leaving the interpretive bottleneck intact; scientists continued to formulate questions, evaluate ...
Michael McCoy, Matthew McCoy
wiley +1 more source
, 2019 Abstract — Educational Administration in Teaching Profession is an educational activity to develop capabilities in the field of administration. science, learning theory and skills implemented long-term aim that is for administrative staff, management or develop the knowledge that has been learned and practiced at school Soekarto Indrafachrudi (2006: 57-
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Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
Journal of Applied Toxicology, Volume 46, Issue 9, Page 3220-3231, September 2026.ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source