Results 101 to 110 of about 26,232 (247)

adm supervisi

, 2020
Supervisi pendidikan adalahusaha memberi layanan kepada guru-guru baik secara individual maupun secara kelompok dalam usaha memperbaiki pengajaran. Kata kunci dari pemberi supervisi pada akhirnya ialah memberikan pelayanan dan bantuan. Ruang lingkup dari supervisi pendidikan adalah akademik dan managerial.
openaire   +2 more sources

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

Cell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou, Mücahit Varlı, Rundong Liu, Jieun Yu, Hyung‐Ho Ha, Jae‐Seoun Hur, Sang Kyum Kim, Hahyun Park, Hangun Kim   +8 more
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

In Silico Analysis of Ocimum Basilicum Flavonoids as Natural Antihypertensive Agent on Angiotensin II Type-1 Receptor (AT1R)

Biology, Medicine & Natural Product Chemistry
Despite the efficacy of antihypertensive medications like ARBs, their adverse effects frequently result in suboptimal adherence. This study investigates the efficacy of flavonoids obtained from herbal sources as natural substitutes for traditional ...
Amir Thalib, Irma Putri Damayanti
doaj   +1 more source

Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling

The Journal of Physiology, EarlyView.
Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley   +1 more source

Detection and Excretion Profile of Retatrutide in Human Plasma and Urine by LC‐HRMS: Implications for Antidoping Analysis

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Retatrutide (LY3437943) is a novel long‐acting triple incretin receptor agonist that targets the glucagon‐like peptide‐1 receptor (GLP‐1R), glucose‐dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR). Its pronounced effects on body composition and metabolic health, combined with increasing off‐label use
Gabriel Reis Alves Carneiro, Isabelle Karine da Costa Nunes, Gustavo Ramalho dos Santos Cardoso, Paola Façanha dos Santos, Monica Costa Padilha, Fábio César Sousa Nogueira, Henrique Marcelo Gualberto Pereira   +6 more
wiley   +1 more source

ADME Parameters

Charts of ADME ...
openaire   +1 more source

Comparative Pharmacokinetics of Six Bioactive Constituents From Danggui Jixueteng Decoction in Normal and Myelosuppressive Rats

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo, Yingjie Liu, Zhiqiang Hu, Xiayu Liu   +3 more
wiley   +1 more source

ADM [PDF]

, 2020
openaire   +1 more source

Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia

The Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 4, December 2026.
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley   +1 more source